Association Between Fatty Acid Amide Hydrolase and Alcohol Response Phenotypes: A Positron Emission Tomography Imaging Study With [11C]CURB in Heavy-Drinking Youth
October 5, 2023
This study finds that lower levels of fatty acid amide hydrolase (FAAH) in the brain predict reduced sensitivity to negative effects of alcohol, greater urges to drink, and greater hazardous drinking in youth. These findings extend preclinical work by implicating the endocannabinoid system in relation to alcohol use disorder risk.