Fall Courses

*Courses with asterisks are appropriate for first year BBSP students.

*601 ENZYME PROPERTIES, MECHANISMS AND REGULATION (3). Prerequisite, CHEM 430, equivalent, or permission of instructor. Focuses on how the shapes of enzymes are designed to optimize the catalytic step and become allosterically modified to regulate activity, on the sources and evolution of transition state stabilization by enzymes, and on the design of artificial enzymes. Fall. Traut (course director), Wolfenden. MWF 10-10:50

*631 ADVANCED MOLECULAR BIOLOGY I (BIOL 631, GNET 631, MCRO 631, PHCO 631) (3). This course focuses on DNA, the molecule most fundamental to life: organization of DNA into genomes, genome replication, recombination, repair, and cellular responses to DNA damage. Fall. A. Sancar (course director), Griffith, Ramsden.

*643 CELL STRUCTURE, FUNCTION AND GROWTH CONTROL I (CBIO 643, MCRO 643, PHCO 643) (3). Required preparation, undergraduate cell biology or biochemistry or permission of the instructor. Comprehensive introduction to cell structure, function, and transformation. Fall. Cheney (course director)

*649 MATHEMATICS AND MACROMOLECULES (1.5)  Prerequisites, permission of course director. Prerequisites, permission of course director. The course is primarily designed for students who need more background in mathematics and macromolecules before taking the core biophysics modules, BIOC 650, 651 and 652. This course will focus on the application of mathematics to topics important in  biophysics, such as thermodynamics and electrostatics. Fall. Lentz (course director) Colleagues. Lecture Course/Paper Discussions

*650 BASIC PRINCIPLES: FROM BASIC MODELS TO COLLECTIONS OF MACROMOLECULES (1.5). Prerequisites, CHEM 430 and two semesters of physical chemistry or permission of the instructor. Basic molecular models and their use in developing statistical descriptions of macromolecular function. Course intended primarily for graduate students. Fall. Lentz (course director) Lecture Course

*BIOC 651 FORCES BETWEEN MACROMOLECULES AND THEIR CONSEQUENCES (1.5). Prerequisites, CHEM 430 and two semesters of physical chemistry or permission of the instructor. Macromolecules as viewed with modern computational methods. Course intended primarily for graduate students. Fall. Lentz (course director), Qi Zhang. Lecture Course/Paper Discussions

BIOC 700 CURRENT TOPICS IN RNA STRUCTURE, FUNCTION, AND TECHNOLOGY (2). Learn about where we came from, who we are  and where we are going. A seminar course in ideas and experiments related to how molecules formed and began to live. Discussions Carter and Swantstrom (co-directors)

*BIOC 701 CRITICAL ANALYSIS & COMMUNICATION IN BIOCHEMISTRY (2). Prerequisites, permission of course director. Critical analysis of current research in conjunction with biochemistry faculty and departmental seminar series. Students select and present research papers, lead discussions, attend seminars and meet with seminar speakers. Course provides an opportunity to become familiar with departmental research as well as state-of-the-art and standard laboratory techniques. Lunch with external seminar speakers. Sudents will create a podcast of at least one of the speakers talks. Fried (course director). M 12–1:30pm. Seminar Series/Paper Discussions

*702 TEACHING IN BIOCHEMISTRY (2) Permission required of course director. Students should be 1st year BBSP students or 2nd year Biochemistry students who want to gain instruction and experience learning how to teach biochemistry. Students will gain experience leading small group session and may present a lecture to undergraduates. Fall. Fried.

*706 BIOCHEMISTRY OF HUMAN DISEASE (3) Prerequisites, Students are expected to have had an undergraduate course in biochemistry or to have gained biochemical principles in a related biology or cell biology course. The objectives of this course are to provide students with a familiarity of contemporary biochemical principles and cutting edge approaches, and increase critical thinking and literature analysis, in the context of human disease. By the end of this course students should be familiar with biochemical causes of the diseases discussed, as well as current and future opportunities for biochemical-based treatments. Fall. Parise (course director), Staff.

715 SCIENTIFIC PRESENTATION (1). Senior graduate students present original research results as a formal seminar. Feedback on presentation effectiveness and style will be provided by faculty instructors and classmates. Summer – registered as Fall. Bergmeier and Neher (co-directors)

725 SIGNAL TRANSDUCTION (PHCO 725) (3). Seminar/discussion course on molecular aspects of the receptors, G-proteins, effector proteins, kinases, and phosphatases that mediate hormone, neurotransmitter, growth factor, and sensory signaling. Fall. Dohlman and Harden (co-directors).

805 MOLECULAR MODELING (MEDC 805) (3). Prerequisites, MATH 231, 232, and CHEM 481. Introduction to computer-assisted molecular design, techniques and theory with an emphasis on the practical use of molecular mechanics and quantum mechanics programs. Fall. Tropsha.

993 MASTER'S THESIS

994 DOCTORAL DISSERTATION