Aziz Sancar, Md, Phd – 2015 Nobel Prize in Chemistry

Just when you figure we know everything, all of a sudden, something comes along, and there is a whole new field to explore."
-Aziz Sancar


Welcome


Welcome to UNC Biochemistry and Biophysics. We have a vigorous, diverse research program and we are home to UNC Nobel Prize winner, Dr. Aziz Sancar. We are the 4th highest NIH funded biochemistry department in the country for 2018. We provide a robust educational and research training program for our graduate students that prepares them for top careers in biochemical and biophysical sciences or related fields. We invite you to explore our website to learn more about our research, graduate program, events and dynamic people who make us great!

Leslie Parise
Leslie Parise, PhD Professor and Chair


Featured News


Leslie Parise

July 2019 Launch of Chair’s Blog “On the Record with LP”

Posted 24 hours ago

Welcome to the first edition of “On the Record with LP.” The purpose of this new blog is to go beyond the news stories on our website to capture more of the many wonderful accomplishments of faculty, trainees and staff in the Department of Biochemistry and Biophysics (BCBP). I would also like to highlight opportunities and issues of importance to biochemistry at UNC and beyond. In future editions, I hope to capture alumni updates as well.

photo of Jean Cook PhD Professor of Biochemistry and Biophysics

Amid concerns about grad student mental health, one university takes a novel approach – Alli Schad & Dr. Jean Cook – Science Magazine

Posted 2 days ago

University campuses are hotbeds of mental health concerns, including among graduate students. But the demand for counseling services often outstrips capacity, according to a 2018 report.

At the University of North Carolina (UNC) in Chapel Hill, students seeking mental health support are frequently referred to providers off campus. “It’s not that they can’t get treatment; they certainly can. … But it’s also not easy to set up,” says Jean Cook, an associate dean of graduate education at UNC who oversees the university’s biological and biomedical sciences Ph.D. program. Students have to arrange transportation, and for grad students there’s an added layer of complexity because they may have to explain why they need to take multiple hours out of their day to travel to an appointment off campus.

Bioc 706 course flier

Incoming BBSP Students can sign up for Bioc 706

Posted 4 days ago

Biochemistry of Human Disease

Tuesdays and Thursdays from 1:00-2:20 PM (3 credit hours)
3007 Genetic Medicine Building

COURSE OBJECTIVES
Learn contemporary biochemical principles, cutting edge approaches, literature analysis, and current and future treatments of human disease.

COURSE FORMAT
Each instructor teaches one lecture and leads one special activity session that incorporates interactive learning with
engaging group work.

Topics include:
-Neurodegeneration
-Cancer
-Infectious Diseases
-Pulmonary Disease
-Cardiovascular Disease

Biochemistry 701 flier

Incoming BBSP Students invited to sign up for Bioc 701

Posted 4 days ago

Critial Analysis & Communication in Biochemistry

(2 credit hours) Monday lecture 12-1:30pm & Tuesday Seminar 11-1pm. Develop a range of communication skills including science podcasting, oral presentations, and roundtable deliberation coupled with in-depth analysis of seminar speaker research. Engage with invited speakers at lunch.

Participants will:

•Select and critique research papers for oral presentations and round-table discussions.
•Discuss research with local speakers attending class.
•Become familiar with state-of-the-art laboratory techniques and experimental approaches in biochemistry, molecular, and cell biology.
Develop a range of communication skills including science podcasting, oral presentations, and roundtable deliberation coupled with in-depth analysis of seminar speaker research. Engage with invited speakers at lunch.
BIOC 701 -Critical Analysis &Communication in Biochemistry (2 credit hours)
Monday Lecture, 12-1:30pm & Tuesday Seminar, 11-1pm

Researchers clock DNA’s recovery time after chemotherapy

Posted 3 weeks ago

The lab of Aziz Sancar, MD, PhD, published a paper in the Journal of Biological Chemistry that could inform the creation of ‘chronochemotherapies’ — strategies aimed using chemo to treat cancer patients at particular times of the day to maximize therapeutic benefit. (Authors: Yanyan Yang PhD, Postdoctoral fellow; Zhenxing Liu PhD, Postdoctoral fellow; Christopher Selby PhD, Research Instructor; Aziz Sancar MD PhD, Distinguished Professor.)

BCBP synergy coffee break photo of 3 people

BCBP Synergy Launched!

Posted 4 weeks ago

To facilitate meetups and networking between members of the Department of Biochemistry and Biophysics (BCBP), we launched BCBP Synergy. Groups of 3-5 randomized individuals are generated with the Strength^n. We are very excited about the future of this program! If you wish to participate in BCBP Synergy, please contact the organizers.

Joshua Strauss and Saskia Neher stand beside the Cryo-EM equipment

The CryoEM Revolution has Arrived

Posted 2 months ago

Installation of a Thermo Scientific Talos Arctica 200 Kv cryo-transmission electron microscope (cryo-TEM) is nearly complete in the Glaxo Research Building at the University of North Carolina at Chapel Hill. Once functioning this summer, this $3-million instrument will bring exciting new capabilities to researchers across the university and others in the RTP area. The Talos Artica will be the centerpiece of the new cryoEM core facility, directed by Joshua Strauss, PhD, assistant professor in the department of biochemistry and biophysics.

photos of Pengda Liu PhD and Shelton Earp MD

Study provides insights behind hyperactivation of key cell proliferation signal

Posted 3 months ago

In a study in Nature Communications, Pengda Liu, PhD, assistant professor of Biochemistry and Biophysics and Shelton Earp, MD, director of UNC Lineberger and the Lineberger Professor of Cancer Research, and their collaborators reported discoveries about a key signaling pathway that can be hyperactive in kidney cancer.

Timechart for UNC parking for night time See also link on this page for accessibility

Weeknight Parking to Begin Aug. 15

Posted 3 months ago

Beginning Aug. 15, UNC Transportation and Parking will charge for parking on campus from Monday evenings through Friday mornings from 5 p.m. until 7:30 a.m. Daytime parking permits for students and employees will be honored at night. Weekend hours are 5 p.m. Friday until 7:30 a.m. Monday and parking will remain available without a permit.

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