Recent News

Could Reading our Circadian Clocks According to DNA Repair Optimize Chemotherapy?

Could Reading our Circadian Clocks According to DNA Repair Optimize Chemotherapy?

For the first time, UNC School of Medicine scientists led by Nobel laureate Aziz Sancar analyzed whole-genome DNA repair in an animal over 24 hours to find which genes were repaired, where exactly, and when, laying the groundwork for a more precise use of anti-cancer drugs.

Could Reading our Circadian Clocks According to DNA Repair Optimize Chemotherapy? - Read More…

How Does Plant DNA Avoid the Ravages of UV Radiation

How Does Plant DNA Avoid the Ravages of UV Radiation

The lab of Aziz Sancar, Sarah Graham Kenan Professor of Biochemistry and Biophysics, reveals the first-ever repair map of an entire multicellular organism to illuminate the inner workings of the plant kingdom’s highly efficient DNA repair system special thanks to the research of Onur Oztas, PhD, Christopher Selby, PhD, Ogun Adebali, PhD.

How Does Plant DNA Avoid the Ravages of UV Radiation - Read More…

Large Aggregates of ALS-causing Protein Might Actually Help Brain Cells

Large Aggregates of ALS-causing Protein Might Actually Help Brain Cells

UNC School of Medicine scientists led by Nikolay Dokholyan, Michael Hooker Distinguished Professor of Biochemistry and Biophysics, add to evidence that small aggregates of SOD1 protein are the brain-cell killing culprits in ALS, but the formation of larger, more visible, and fibril-like aggregates of the same protein may protect brain cells.

Large Aggregates of ALS-causing Protein Might Actually Help Brain Cells - Read More…

Brian Strahl Awarded NIGMS Outstanding Investigator Grant

Brian Strahl Awarded NIGMS Outstanding Investigator Grant

Congratulations to Brian Strahl, Professor & Vice-Chair of the Department of Biochemistry & Biophysics, for being selected to receive an R35 Maximizing Investigators’ Research Award (MIRA) from the National Institutes of Health.

Brian Strahl Awarded NIGMS Outstanding Investigator Grant - Read More…

Prognostic tool could identify high-risk breast cancer patients

Prognostic tool could identify high-risk breast cancer patients

In the journal Cell Chemical Biology, researchers led by Biochemistry and Biophysics Associate Professor and Faculty Director, Quantitative Proteomics Center for Disease Marker Discovery, Xian Chen, PhD, report on potential prognostic tool that could be used to identify high-risk patients within particular subtypes of breast cancer.

Prognostic tool could identify high-risk breast cancer patients - Read More…

Researchers define structure, function of enzyme key to blood cancers

Researchers define structure, function of enzyme key to blood cancers

In the journal Nature, Greg Wang, PhD, assistant professor of Biochemistry and Biophysics and Cell biology Program, and colleagues reported findings about the structure and function of the DNMT3A enzyme complex, which helps control gene expression.

Researchers define structure, function of enzyme key to blood cancers - Read More…

We rank 4th nationally in NIH funding in 2017!

The Department ranks fourth among all Biochemistry departments in the US, (both public and private institutions not just public) in 2017.

We rank 4th nationally in NIH funding in 2017! - Read More…

Gene therapy researchers find viral barcode to cross the blood-brain barrier

Gene therapy researchers find viral barcode to cross the blood-brain barrier

Congratulations to Aravind Asokan PhD, Assistant Professor of Genetics with a Joint Appointment in Biochemistry and Biophysics and Lineberger Comprehensive Cancer Center member who led UNC scientists to reveal how certain gene-carrying AAV vectors can penetrate the brain more efficiently to treat brain and spinal cord conditions, while reducing liver payload.

Gene therapy researchers find viral barcode to cross the blood-brain barrier - Read More…

Strahl named Smithies Investigator

Strahl named Smithies Investigator

Congratulations Brian Strahl, PhD, professor and vice chair of the department of biochemistry and biophysics, and Jen Jen Yeh, MD, professor and vice chair of research for the department of surgery, who were selected by the UNC School of Medicine for the annual award in honor of Oliver Smithies, UNC’s first Nobel Prize winner.

Strahl named Smithies Investigator - Read More…

Holiday Party 2017 Highlights

Holiday Party 2017 Highlights

Our department gathered at the Carolina Club to celebrate the holidays on December 13, 2017.

Holiday Party 2017 Highlights - Read More…

UNC Scientists Discover Proteins Keeping Stem Cells in their Undifferentiated State

UNC Scientists Discover Proteins Keeping Stem Cells in their Undifferentiated State

The lab of Jean Cook, PhD, in the Department of Biochemistry and Biophysics, found how a chain of proteins called an MCM complex could enable the fast cell-division that makes some forms of cancer so dangerous. The study first author Jacob Matson, a PhD candidate in the Cook lab performed most of the experiments.

UNC Scientists Discover Proteins Keeping Stem Cells in their Undifferentiated State - Read More…

Graduate student Tom Lane receives his PhD

Graduate student Tom Lane receives his PhD

Tom Lane under the direction of Dr. Kevin Slep, successfully defended his dissertation on November 3, 2017 and received his PhD!

Graduate student Tom Lane receives his PhD - Read More…

Campbell receives Liebscher Distinguished Professorship

Campbell receives Liebscher Distinguished Professorship

Congratulations to Sharon Campbell who has been appointed the Gary F. Liebscher Distinguished Professor of Biochemistry and Biophysics, effective November 1.

Campbell receives Liebscher Distinguished Professorship - Read More…

Dokholyan Meets with President of Armenia

Dokholyan Meets with President of Armenia

Nikolay Dokholyan, Ph.D. from Biochemistry/Biophysics and Alexander "Sasha" Kabanov, Ph.D. from Pharmacology met with the President of Armenia on Nov. 8, 2017.

Dokholyan Meets with President of Armenia - Read More…

Halloween 2017 - special thanks to...

Halloween 2017 - special thanks to...

Thanks to students Hanna Trzeciakiewicz (Cohen Lab) and Aaztli Coria (Laederach Lab) and office staff Jamie DeSoto, Lynn Ray, and Susan Sarvis for organizing a fun Halloween party. Prizes for best individual costume went to Dr. Edward Moreira Bahnson with the white skeleton face and bow tie. Best group costume went to the Parise Lab with the mice costumes. Winner of the Pumpkin weight contest went to Bobby Lee (Bergmeier Lab). Actual weight was 33 pounds. Winner of the Candy Corn Count went to Aleksandra Skrajna (McGinty Lab). Actual count was 1340 candy corns.

Halloween 2017 - special thanks to... - Read More…

Parise helps bring Nobel Prize winning CryoEM technology to UNC and RTP

Parise helps bring Nobel Prize winning CryoEM technology to UNC and RTP

Leslie Parise has been working for years to bring the technology that won a Nobel Prize. "We are going from nothing to three instruments."

Parise helps bring Nobel Prize winning CryoEM technology to UNC and RTP - Read More…

Grad Student Cassandra Hayne receives her PhD!

Grad Student Cassandra Hayne receives her PhD!

Hayne successfully defended her dissertation and received her PhD on August 31, 2017.

Grad Student Cassandra Hayne receives her PhD! - Read More…

The Science of Fluoride Flipping

The Science of Fluoride Flipping

Zhang lab develops a new imaging technique helps UNC researchers study tiny, time-sensitive biological processes – the crucial underpinnings of human health and disease.

The Science of Fluoride Flipping - Read More…

Solar Eclipse Viewing Party

Solar Eclipse Viewing Party

The Biochemistry and Biophysics department gathered together to view the solar eclipse on August 21, 2017 with cereal box projectors and protective eclipse glasses. The moon blotted out 93% of the sun. Monday's eclipse was the first one since 1918 that traveled across the United States.

Solar Eclipse Viewing Party - Read More…

Changes to School of Medicine VPN Access

Changes to School of Medicine VPN Access

Beginning on Monday, September 18, 2-Step Verification will be required to utilize the UNC School of Medicine Campus VPN to access resources from off-campus locations. The Cisco VPN Client is typically used when off campus to access shared network resources such as the J: drive, and on-campus printers, as well as connecting to your office desktop using the Remote Desktop Connection. Read more for information on registering for 2-Step Verification (Duo).

Changes to School of Medicine VPN Access - Read More…