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Research: The Relentless Pursuit of a Better World

From the bench to the bedside, Carolina’s research enterprise is among the nation’s most prolific. Having made extraordinary advances in fields such as biomedical engineering, cancer, and big data, the University has become a worldwide leader among premier research universities for discoveries and contributions that improve the quality of life for all.

UNC Core Facilities

UNC has over 80 core facilities that support $1.2 billion research enterprise! The University of North Carolina at Chapel Hill ranked 29th in the world and 20th in the United States among global universities, according to the 2021 Academic Ranking of World Universities (ARWU) released by the ShanghaiRanking Consultancy on Aug. 15. UNC Research Core Facilities are shared resources which offer a wide range of services to the research community, including cutting edge technologies, high end instrumentation, technical support, and education.

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Faculty Areas of Research

Cellular Biology

The Department of Cell Biology and Physiology conducts cutting-edge, innovative research that advances the discipline of cell biology and physiology, with an emphasis on topics that contribute to the improvement of human health. The UNC Department of Cell Biology and Physiology is nationally-recognized and ranked #2 in the country for Medical Research.

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Genetics & Molecular Biology

Matson Cook cells eLife 2017

Genetics is both a discipline and an experimental approach (manipulation of genes or the genetic material). Today, most geneticists include work at the molecular level by manipulating RNA or DNA… or entire genomes. Our department is strong in both model organism genetics and genomics.

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Biophysical Studies

The Molecular & Cellular Biophysics training program is an NIH funded training program for quantitative and physical biology. The MCBP exists both to provide a flexible vehicle for training graduate students who share a passion for biophysics and to enhance the research and training community of its diverse group of faculty and students.

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The department has broad research strengths, but with particular emphasis in four areas:
1) chromatin biochemistry, DNA processes including replication, repair, recombination, remodeling and transcription; 2) cell signaling and cell cycle control, trafficking and retroviruses; 3) enzymology, protein biochemistry and biophysics and, 4) proteomic, structural and computational biology.

Faculty research areas:

  • Cell Biology; Cell Cycle; Cell Signaling; Trafficking and Retroviruses
  • Chromatin Biochemistry, DNA Replication, Repair and Recombination; Transcription and Gene Regulation
  • Enzymology; Protein Biochemistry; Biophysics; Protein Engineering
  • Proteomics; Structural Biology; Computational Biology
  • Above in context of cancer, cardiovascular disease, neurological disorders, HIV and

Cardiovascular Biology, Drug Discovery, Genomics, Molecular Biology, Structural Biology, Cancer Biology, Drug Delivery, Genetics, Nanomedicine, Pathology, Physiology, Systems Biology, Chemical Biology, Plant Biology, Toxicology, Bioinformatics, Nanomedicine, X-ray Crystallography, Biomolecular NMR, Pharmacology, Pharmacy, Virology, Molecular Dynamics, enzyme kinetics, Microscopy, translational medicine, and more.