Welcome to the Mac-in-Fac!

Biomolecular Interactions, light scattering, SPR, biosensor, SPR-based biosensor, Proteon, Proteon XPR36, Biacore 3000, analytical ultracentrifugation, Auto-ITC200, ITC, DSC, microcalorimeters, fluorescence plate reader, circular dichroism, fluorimeter, molecular weight determination, DynaPro plate reader

The Macromolecular Interactions Facility (commonly known as the Mac-In-Fac) is a core facility of the University of North Carolina at Chapel Hill. It provides instrumentation and resources for biophysical characterization of biological macromolecules and their interactions with cognate ligands. Core instrumentation include: surface plasmon resonance-based biosensors; analytical ultracentrifuges with absorbance, interference, and fluorescence detection systems; a spectrofluorometer; differential scanning and isothermal titration calorimeters; circular dichroism spectropolarimeters, static and dynamic light scattering instruments, and a fluorescence microplate reader. The facility is open to all researchers in the Triangle area on a first-come-first-serve basis; however, preference is given to UNC researchers.