X-Ray Crystallography

X-ray crystallography is the principal technique used to determine three-dimensional structures of biological macromolecules. The central goal of the UNC Crystallography Core Facility is to provide the support and infrastructure necessary to enable individual investigators of any experience level to initiate and successfully complete a structural biology project.

The facility is state of the art, offering a variety of services in these three areas:

crystals lyso-diffraction density-gray
Crystallization X-Ray Diffraction
Data Collection
Structure Determination
and Refinement

The primary mission of the MX Facility is to work with researchers here at UNC, however, we are also able to work with researchers at non-UNC academic institutions and commercial companies.

cite & submit

We obtain on-going support from the UNC Lineberger Comprehensive Cancer Center through the University Cancer Research Fund and the Cancer Center Support Grant. Consequently, publications supported by the UNC Center for Structural Biology must acknowledge NIH grant P30CA016086 and be submitted to PubMed Central in compliance with the NIH Public Access Policy.

Suggested acknowledgement: “This work was supported by the National Cancer Institute of the National Institutes of Health under award number P30CA016086. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.”