Journal Highlights
| Journal Covers and highlighted articles by Pharmacology faculty. Click on images for larger views. |
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Samulski Lab - Paper Published in Science Translational Medicine, December 2012. "Follow-Up After Gene Therapy for Canavan Disease." Leone et al., Science Translational Medicine Vol. 4, Issue 165, p. 165ra163, 2012. DOI: 10.1126/scitranslmed.3003454. doi:10.1038/nsmb.2377. online article |
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Jobin Lab - Paper Published in Science, October, 2012. "Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota." Arthur et al., Science 338 (6103): 120-123, 2012. doi:10.1038/nsmb.2377. online article |
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Wang Lab - Paper Published in Nature Sturctural & Molecular Biology Sept. 16, 2012. "Intronic splicing enhancers, cognate splicing factors and context-dependent regulation rules." Nature Struct Mol Biol., published online doi:10.1038/nsmb.2377. online article |
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Elston Lab - Paper Nominated as Being of Special Significance by F1000. 7, 2012 "Positive roles for negative regulators in the mating response of yeast." Mol.Sys. Biol., June 5, 2012. online article Anuj Kumar and Cole Johnson's article in F1000 Research on the paper's special significance for the field of Genomics & Genetic: July 20, 20112. |
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Johnson Lab - Cell Stem Cell publication May 6, 2011. "MAP3K4/CBP-Regulated H2B Acetylation Controls Epithelial-Mesenchymal Transition in Trophoblast Stem Cells." Cell Stem Cell 8(5): 525-537, 2011. online article Commentary: "An Epigenetic Mark that Protects the Epithelial Phenotype in Health and Disease" in Cell Stem Cell 8(5): 462-463, 2011. online article |
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Dohlman Lab - Science Signaling publication February 8, 2011. Highlighted in Science Editor's Choice February 25, 2011 as "Cell Signaling: Receptor Free Signaling." "The Crystal Structure of a Self-Activating G Protein Alpha Subunit Reveals Its Distinct Method of Signal Initiation." Science Signaling 4(159): ra8, 2010. online article |
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Dohlman Lab - Molecular Cell publication June 11, 2010. Highlighted in Science Signaling Editor's Choice June 29, 2010 as "G Protein Signaling Is Not a Done Deal." "Systematic Analysis of Essential Genes Reveals Important Regulators of G Protein Signaling." Molecular Cell 38(5): 746-757, 2010. online article |
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Harden Lab and Sondek Lab - Science publication October 21, 2010. "Kinetic Scaffolding Mediated by a Phospholipase C-β and Gq Signaling Complex." Science 330: 974-980, 2010. online article |
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Whitehurst Lab - Cover of Molecular and Cellular Biology, Nov., 2010. "Symplekin Specifies Mitotic Fidelity by Supporting Microtubule Dynamics." Mol Cell Biol. 30(21):5135-44, 2010. online article |
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Whitehurst Lab - Publication highlighted on cover of Cancer Research, October 1, 2010. "Tumor Antigen Acrosin Binding Protein Normalizes Mitotic Spindle Function to Promote Cancer Cell Proliferation." Cancer Res. 70(19): 7652-7661, 2010. online article |
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Hahn Lab - Research with biosensors and photoactivatable proteins highlighted in the 10th Anniversary Issue of Nature Reviews Molecular Cell Biology October 2010, 11(10): 680. "Sensing and Controlling Protein Dyanmics" by Katherine H. Wrighton. article "The work of Klaus Hahn has transformed biosensors into major cell biological tools that have revealed new and important insights." ~Rick Horwitz, University of Virginia |
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Hahn Lab - Research using the LOV protein to control the ability to move and activiate cells with light is highlighted in the Fall 2010 edition of Endeavors, UNC's Research and Creative Activity Magazine. "Send in the Cells" by Susan Hardy article Hahn Lab cell cinema movies of moving cells with light |
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Cox and Der Labs - Small GTPases Cover Vol 1, Issue 1, July-August, 2010 "Ras History: The Saga Continues." Small GTPases 1(1):2-27. |
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Hahn Lab - Nature Biotechnology highlighted publication, June 27, 2010 "Engineered allosteric activation of kinases in living cells." Nature Biotechnology June 27, 2010 [epub before publication]. |
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Johnson Lab - Cover of Journal of Biological Chemistry, April 16, 2010 "Rho kinase inhibition rescues the endothelial cell cerebral cavernous malformation phenotype." J Biol Chem 285:11760-11764. Online Article |
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Cox Lab - Cover of Molecular and Cellular Biology, Feb., 2010 Online cover image and description Related article: "The transforming Rho family GTPase Wrch-1 disrupts epithelial cell tight junctions and epithelial morphogenesis." Mol Cell Biol 29(4): 1035-1049. Online Article |
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McCarthy Lab - Science publication, March 5, 2010 "Hippocampal Short- and Long-term Plasticity are not Modulated by Astrocyte Ca2+ Signaling." Science 327(5970): 1250-1254, 2010. Online Article in Science |
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Roth Lab - Nature publication, Nov. 12, 2009 "Predicting new molecular targets for known drugs." Nature 462(7270):175-81, 2009. Online Article |
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Polleux Lab - Cover of Cell, September 4, 2009 "The F-BAR domain of srGAP2 induces membrane protrusions required for neuronal migration and morphogenesis." Cell 138:990-1004. Online Article |
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Hahn Lab - Highlighted Nature publication - Published back to back in same issue with Nature paper listed below. |
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Hahn and Johnson Labs - Nature publication - Published back to back in same issue with Nature paper listed above. |
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Hahn Lab - Cover of Immunology |
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Samulski Lab - Cover of Virology "Enhancement of adeno-associated virus infection by mobilizing capsids into and out of the nucleolus." Abstract |
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Harden and Sondek Labs - Cover of Molecular Cell "General and versatile autoinhibition of phospholipase C isozymes. " Abstract |
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Samulski Lab - Cover of Molecular Therapy "Engineering and Selection of Shuffled AAV Genomes: A New Strategy for Producing Targeted Biological Nanoparticles" Abstract
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David Siderovski and Francis Willard are Guest Editors for a two-issue set of papers in the journal Combinatorial Chemistry and High Throughput Screening describing "new technologies and new opportunities for screening compound libraries for modulators of GPCR signaling." Their editorial introduction to the June 2008 issue can be read here. |
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Samulski Lab - Cover of Virology "Surface loop dynamics in adeno-associated virus capsid assembly." Abstract |
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Zhang Lab - Cover of Cancer Cell "Targeted inactivation of Mdm2 E3 ubiquitin ligase activity in the mouse reveals novel mechanistic insights into p53 regulation." Abstract |
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Samulski Lab - Cover of Virology "Surface-exposed adeno-associated virus Vp1-NLS capsid fusion protein rescues infectivity of noninfectious wild-type Vp2/Vp3 and Vp3-only capsids but not that of fivefold pore mutant virions." Abstract |
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Richard Mailman - Cover of Trends in Pharmacological Sciences "GPCR functional selectivity has therapeutic impact" Abstract |
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McCarthy Lab - Neuron publication "Selective Stimulation of Astrocyte Calcium In Situ Does Not Affect Neuronal Excitatory Synaptic Activity" Abstract |
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Gary Johnson is Guest Editor for the May 14, 2007 issue of Oncogene, along with DN Dhanasekaran. Oncogene issue |
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Siderovski Lab - Research on G-alpha proteins is highlighted in the Spring 2007 edition of Endeavors, UNC's Research and Creative Activity Magazine. |
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Wang Lab - Cover of Molecular Cell "General and specific functions of exonic splicing silencers in splicing control."Abstract |
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Johnson Lab - Cover of Journal of Biological Chemistry "MEKK4 is an effector of the embryonic TRAF4 for JNK activation." Abstract |
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Parise Lab - Research on sickle cell adhesion is highlighted in the Spring 2006 edition of Endeavors, UNC's Research and Creative Activity Magazine. "Getting Past Stickiness" by Jan McColm Article Photo of Leslie Parise, Julie Brittain and Sheritha Lee. |
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Hahn Lab - Cover of Cytometry "Functional Proteometrics for Cell Migration" Abstract |
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Cox Lab - Cover of Molecular Cell "PKC Regulates a Farnesyl-Electrostatic Switch on K-Ras that Promotes its Association with Bcl-XL on Mitochondria and Induces Apoptosis" Abstract |
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Hahn Lab - Nature publication "Spatiotemporal dynamics of RhoA activity in migrating cells" Abstract |
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Nicholas Lab - Selected as the highlight paper in Journal of Bacteriology |
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Parise Lab - Cover of the Journal of Cell Biology |
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Sondek Lab - Cover of Structure |
