The Cell article from the Hahn and Elston labs describes a new approach to visualize the changing conformations of individual molecules in living cells, affording insight into the organization and dynamics of kinase signaling.
Tom Kash’s lab shows how neurons in two brain regions use dopamine to promote pain responses differently in male and female mice in a paper in Neuron this week.
Michael Emanuele’s and Nicholas Brown’s Labs have published a paper in PLOS Biology! Check it out!
Congratulations to Jonathan Schisler who co-authored two papers published in Cell and Cell Reports a week apart detailing the results of NASA space flight studies.
The Mauro Calabrese & Jonathan Schisler labs contributed to a genetics study published in the Nov. 2020 issue of Genetics to improve rigor and reproducibility in mouse research.
The Nature Communications paper details how the cardioprotective effects of protein kinase G are mediated by the protein quality control enzyme CHIP, reducing proteotoxicity in heart failure. Becky Sanchez is coauthor.
Congratulations to Blossom Damania and her lab, including PHCO grad student and co-author, Danielle Chappell, on the publication in Cell Reports of a paper on “High-density amplicon sequencing identifies community spread and ongoing evolution of SARS-CoV-2 in the Southern United States.”
Juan Song’s lab publishes a paper in Neuron showing the cell-signaling role of a neuropeptide called cholecystokinin, which is important in regulating neural stem cells and creating adult-born neurons within the hippocampus of the brain.
This work, published in Cell and led by the Roth lab sets the stage for the discovery of new kinds of antidepressants, anti-anxiety drugs, and treatments for substance use disorders. Kuglee Kim is co-first author on the paper.
Congratulations to Pharmacology graduate student Raquel C. Martinez Chacin, who is first author on a paper published in Nature Structural and Molecular Biology Journal! The paper by the Brown Lab in collaboration with the Emanuele Lab, Jean Cook lab, and other researchers at UNC and the Research Institute of Molecular Pathology (IMP) in Vienna was published May 11, 2020!
