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Professor, Departments of Psychiatry and Pharmacology

Research Interests

More on Dr. Breese’s Research History

  • Molecular Basis for Ethanol-GABA Interactions
  • Molecular Basis of Ethanol Action on NMDA Receptors
  • CNS Transmitters Involved in Withdrawal-Induced Anxiety Gene Therapy and Seizures
  • Theory of the Role of Stress in Relapse in Alcoholism
  • Neurobiology of Lesch-Nyhan Disease
  • Neurobiology of Anti-Depressant Drugs
  • Neurobiology of D1 Dopamine Receptors

Recent Publications

A mouse model for chronic pain-induced increase in ethanol consumption. Butler RK, Knapp DJ, Ulici V, Longobardi L, Loeser RF, Breese GR.Pain. 2017 Mar;158(3):457-462. doi: 10.1097/j.pain.0000000000000780 PMID:27918314

Age-related differences in anxiety-like behavior and amygdalar CCL2 responsiveness to stress following alcohol withdrawal in male Wistar rats. Harper KM, Knapp DJ, Park MA, Breese GR. Psychopharmacology (Berl). 2017 Jan;234(1):79-88. doi: 10.1007/s00213-016-4439-y. PMID:27665607

Stress and Withdrawal from Chronic Ethanol Induce Selective Changes in Neuroimmune mRNAs in Differing Brain Sites. Knapp DJ, Harper KM, Whitman BA, Zimomra Z, Breese GR. Brain Sci. 2016 Jul 27;6(3). pii: E25. doi: 10.3390/brainsci6030025. PMID:27472367

Persistent adaptation by chronic alcohol is facilitated by neuroimmune activation linked to stress and CRF. Breese GR, Knapp DJ. Alcohol. 2016 May;52:9-23. doi: 10.1016/j.alcohol.2016.01.005. PMID:27139233

The Use of Perinatal 6-Hydroxydopamine to Produce a Rodent Model of Lesch-Nyhan Disease. Knapp DJ, Breese GR. Curr Top Behav Neurosci. 2016;29:265-77. doi: 10.1007/7854_2016_444. PMID:27029809


Click here for a full list of publications from PubMed

  • Research Scientist Neurosciences Center