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Research Assistant Professor

Bowles Center for Alcohol Studies

Department of Pharmacology

Office: 3005 Thurston Bowles Bldg CB#7178

Email: rvetreno@email.unc.edu

Biographical Sketch: RPV Biosketch 

 

 

Research Interests:

My broad scientific goal is to understand how exposure to alcohol and other drugs of abuse during adolescence causes alterations to neurobiology that persist into adulthood. One focus of my research is to elucidate the neuroimmune and epigenetic mechanisms underlying adolescent binge alcohol-induced disruption of basal forebrain cholinergic neurocircuitry in adulthood. A second focus of my research is to investigate a connection between lasting adolescent binge drinking-induced neuroimmune priming with the etiology of basal forebrain neuropathology in Alzheimer’s disease.

 

Publications:

  1. Long-lasting microbial dysbiosis and altered enteric neurotransmitters in adult rats following adolescent binge ethanol exposure.

Vetreno RP, Massey V, Crews FT. PMID: 31880056

2. Neuroimmune and epigenetic mechanisms underlying persistent loss of hippocampal neurogenesis following adolescent intermittent ethanol exposure.

Macht V, Crews FT, Vetreno RP. PMID: 31778865

3. Mechanisms of Persistent Neurobiological Changes Following Adolescent Alcohol Exposure: NADIA Consortium Findings.

Crews FT, Robinson DL, Chandler LJ, Ehlers CL, Mulholland PJ, Pandey SC, Rodd ZA, Spear LP, Swartzwelder HS, Vetreno RP. PMID: 31335972

4. Neuroimmune and epigenetic involvement in adolescent binge ethanol-induced loss of basal forebrain cholinergic neurons: Restoration with voluntary exercise.

Vetreno RP, Bohnsack JP, Kusumo H, Liu W, Pandey SC, Crews FT. PMID: 30779268

5. Adolescent binge ethanol-induced loss of basal forebrain cholinergic neurons and neuroimmune activation are prevented by exercise and indomethacin.

Vetreno RP, Crews FT.  PMID: 30296276