BCBP Seminar: Lindsay Case PhD
September 20 @ 11:00 am - 12:00 pm
Massachusetts Institute of Technology (MIT)
Host: Rebecca Berlow
Research: Case lab studies how molecules are concentrated and organized at the plasma membrane to regulate transmembrane signaling. We study how cells regulate the spatial organization of signaling molecules at the plasma membrane to control downstream signaling. For example, receptor clustering and higher-order assembly with cytoplasmic proteins can create compartments with unique biochemical and biophysical properties. We use quantitative experimental approaches from biochemistry, molecular biophysics, and cell biology to study transmembrane signaling pathways and how they are misregulated in diseases like cancer.