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Seminar: Shan Zha (Columbia University)

April 23 @ 11:00 am - 12:00 pm

text "BCBP Spring 2024 Seminar Series Presents Inhibition is not deletion in DNA damaging therapies Shan Zha, MD, Ph.D. James A Wolff Professor of Pediatrics, Pathology and Cell Biology and of Microbiology and Immunology Institute for Cancer Genetics and in the Herbert Irving Comprehensive Cancer Center, Columbia University The Zha lab investigates how defects in DNA repair and DNA damage responses impact normal immune system development, lymphomagenesis, and treatment responses. The lab has developed cutting-edge technologies, including high-throughput translocation sequencing, sing cell-seq, multi-color flow-cytometry, CRISPR-based depletion and activation screens, high-content live-cell imaging, and a collection of over sixty-five unique mouse models, including the serial of mouse models expressing catalytically inactive ATM, ATR, DNA-PKcs, and now PARP1 and PARP2, which revealed unexpected structural function of DNA damage response factors." Photo of Dr. Zha.

Shan Zha, M.D., Ph.D., James A Wolff Professor of Pediatrics, Pathology and Cell Biology and of Microbiology and Immunology (in the Institute for Cancer Genetics and in the Herbert Irving Comprehensive Cancer Center

Department of Pathology and Cell Biology

Columbia University

Title: “Inhibition is not deletion in DNA damaging therapies”

Host: Xian Chen

Details

Date:
April 23
Time:
11:00 am - 12:00 pm
Event Categories:
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Venue

1131 Bioinformatics
130 Mason Farm Road
Chapel Hill, NC 27514 United States

Organizer

Rhonda Strickland
Email
rbrann@email.unc.edu