Carolina-Duke Core Partnership: Using UNC Cores
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Participating UNC Chapel Hill Cores
The following cores will offer the “breakeven” cost recovery rate to Duke labs. This may be limited to certain equipment or rates, specified int he “Included Technology” section below.
| Core Name and Website | Core Director Name | Core Contact E-mail | Description | Included Technology: |
| Animal Models Core | Dr. Dale Cowley | dcowley@med.unc.edu | A full suite of genome engineering services for the generation of genetically modified mouse and cell line models for biomedical research including CRISPR/Cas9, ES Cell Gene Targeting, transgenic mouse services, and more. | All |
| Website | Core Director Name | Core Contact E-mail | Description | Included Technology: |
| Biomolecular NMR Laboratory | Dr. Stu Parnham | stitch@ad.unc.edu | Bruker Avance III HD 500, 600, 700, and 850 MHz spectrometers as well as training, consultation, and concierge data collection by the core director as well as access to Fragment-based Drug Discovery, using the cores ‘In-House’ 19F and 1H fragment libraries, and metabolomics. | All |
| Core Name and Website | Core Director Name | Core Contact E-mail | Description | Included Technology: |
| Bioinformatics and Analytics Research Collaborative | Dr. Austin Hepperla | hepperla@unc.edu | Our team will meet with you before, during and after your project to assist with experimental design, data processing, data analysis and interpretation, figure generation, and manuscript and/or grant preparation. We specialize in high-throughput sequencing and gene expression data, image analysis data, and other biological data. | All |
| Core Name and Website | Core Director Name | Core Contact E-mail | Description | Included Technology: |
| High-Throughput Sequencing Facility | Dr. Sam Pattenden | pattenden@unc.edu | HTSF provides access to a full suite of genomic technologies. Oxford Nanopore can produce ultra-long read sequencing reads, limited by DNA length/quality. In our hands we regularly generate reads >100kb. There are a host of applications, including: Rapid sequence identification, utilizing long reads for improved genome assembly, analysis of full length RNA transcripts from cDNA (PCR and PCR-free), direct sequencing of RNA molecules, metagenomic analysis, structural variant detection, and copy number detection in complex regions | Oxford Nanopore Sequencing on the GridION platform |
| Core Name and Website | Core Director Name | Core Contact E-mail | Description | Included Technology: |
| Human Pluripotent Stem Cell Core | Dr. Adriana Beltran | beltran@med.unc.edu | The Human Pluripotent Cell Core services are designed to accelerate the pace of scientific discovery and application in the field of stem cell research by providing researchers with access to high-quality iPSCs, differentiated cells, and expert support. | All |
| Core Name and Website | Core Director Name | Core Contact E-mail | Description | Included Technology: |
| Microbiome Core | Dr. Andrea Azcarate-Peril | azcarate@med.unc.edu | The mission of the UNC Microbiome Core is to provide the research community with the facilities and expertise to characterize complex microbial communities and microbial interactions. The Core has state of the art instrumentation and extensively trained personnel that provide support from experimental design to data analysis | All |
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| Core Name and Website | Core Director Name | Core Contact E-mail | Description | Included Technology: |
| Vector Core | Genlin Hu | ghu@email.unc.edu | The UNC Vector Core offers an extensive inventory of premade AAV vectors available in multiple serotypes. Additionally, the core can provide custom vector production. | All |
Duke PIs who are currently customers of other core facilities will continue to receive the rates communicated by those core facilities. Requests to add cores to this list may be considered after the 2026 trial period as long as it does not create direct competition with existing core facilities at Duke University and with approval of both UNC Chapel Hill and Duke University leadership.