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Department of Genetics faculty and collaborators published nine papers during the first half of March 2017.

A Reverse Genetics Platform That Spans the Zika Virus Family Tree.

Widman DG, Young E, Yount BL, Plante KS, Gallichotte EN, Carbaugh DL, Peck KM, Plante J, Swanstrom J, Heise MT, Lazear HM, Baric RS.
MBio. 2017 Mar 7;8(2). pii: e02014-16. doi: 10.1128/mBio.02014-16.
PMID: 28270583

Genome-Wide Association Study of Post-Traumatic Stress Disorder in Two High-Risk Populations.

Melroy-Greif WE, Wilhelmsen KC, Yehuda R, Ehlers CL.
Twin Res Hum Genet. 2017 Mar 6:1-11. doi: 10.1017/thg.2017.12. [Epub ahead of print] PMID: 28262088

Genetic Regulation of Adipose Gene Expression and Cardio-Metabolic Traits.

Civelek M, Wu Y, Pan C, Raulerson CK, Ko A, He A, Tilford C, Saleem NK, Stančáková A, Scott LJ, Fuchsberger C, Stringham HM, Jackson AU, Narisu N, Chines PS, Small KS, Kuusisto J, Parks BW, Pajukanta P, Kirchgessner T, Collins FS, Gargalovic PS, Boehnke M, Laakso M, Mohlke KL, Lusis AJ.
Am J Hum Genet. 2017 Mar 2;100(3):428-443. doi: 10.1016/j.ajhg.2017.01.027.
PMID: 28257690

Comprehensive analysis of The Cancer Genome Atlas reveals a unique gene and non-coding RNA signature of fibrolamellar carcinoma.

Dinh TA, Vitucci EC, Wauthier E, Graham RP, Pitman WA, Oikawa T, Chen M, Silva GO, Greene KG, Torbenson MS, Reid LM, Sethupathy P.
Sci Rep. 2017 Mar 17;7:44653. doi: 10.1038/srep44653.
PMID: 28304380

A microengineered collagen scaffold for generating a polarized crypt-villus architecture of human small intestinal epithelium.

Wang Y, Gunasekara DB, Reed MI, DiSalvo M, Bultman SJ, Sims CE, Magness ST, Allbritton NL.
Biomaterials. 2017 Mar 6;128:44-55. doi: 10.1016/j.biomaterials.2017.03.005. [Epub ahead of print] PMID: 28288348

NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth.

Chen L, Wilson JE, Koenigsknecht MJ, Chou WC, Montgomery SA, Truax AD, Brickey WJ, Packey CD, Maharshak N, Matsushima GK, Plevy SE, Young VB, Sartor RB, Ting JP.
Nat Immunol. 2017 Mar 13. doi: 10.1038/ni.3690. [Epub ahead of print] PMID: 28288099

Root microbiota drive direct integration of phosphate stress and immunity.

Castrillo G, Teixeira PJ, Paredes SH, Law TF, de Lorenzo L, Feltcher ME, Finkel OM, Breakfield NW, Mieczkowski P, Jones CD, Paz-Ares J, Dangl JL.
Nature. 2017 Mar 15. doi: 10.1038/nature21417. [Epub ahead of print] PMID: 28297714

Annealing of Complementary DNA Sequences During Double-Strand Break Repair in Drosophila Is Mediated by the Ortholog of SMARCAL1.

Korda Holsclaw J, Sekelsky J.
Genetics. 2017 Mar 3. pii: genetics.117.200238. doi: 10.1534/genetics.117.200238. [Epub ahead of print] PMID: 28258182