Department of Genetics faculty, postdocs, students and collaborators published nine papers during October 6-19, 2019.

Contributions of common genetic variants to risk of schizophrenia among individuals of African and Latino ancestry.
Bigdeli TB, Genovese G, Georgakopoulos P, Meyers JL, Peterson RE, Iyegbe CO, Medeiros H, Valderrama J, Achtyes ED, Kotov R, Stahl EA, Abbott C, Azevedo MH, Belliveau RA, Bevilacqua E, Bromet EJ, Byerley W, Carvalho CB, Chapman SB, DeLisi LE, Dumont AL, O’Dushlaine C, Evgrafov OV, Fochtmann LJ, Gage D, Kennedy JL, Kinkead B, Macedo A, Moran JL, Morley CP, Dewan MJ, Nemesh J, Perkins DO, Purcell SM, Rakofsky JJ, Scolnick EM, Sklar BM, Sklar P, Smoller JW, Sullivan PF, Macciardi F, Marder SR, Gur RC, Gur RE, Braff DL; Consortium on the Genetics of Schizophrenia (COGS) Investigators, Nicolini H, Escamilla MA, Vawter MP, Sobell JL, Malaspina D, Lehrer DS, Buckley PF, Rapaport MH, Knowles JA; Genomic Psychiatry Cohort (GPC) Consortium, Fanous AH, Pato MT, McCarroll SA, Pato CN.
Mol Psychiatry. 2019 Oct 7. doi: 10.1038/s41380-019-0517-y. [Epub ahead of print]
PMID: 31591465

 

Genetic Control of Expression and Splicing in Developing Human Brain Informs Disease Mechanisms.
Walker RL, Ramaswami G, Hartl C, Mancuso N, Gandal MJ, de la Torre-Ubieta L, Pasaniuc B, Stein JL, Geschwind DH.
Cell. 2019 Oct 17;179(3):750-771.e22. doi: 10.1016/j.cell.2019.09.021.
PMID: 31626773

 

Transcriptional profiling of the murine airway response to acute ozone exposure.
Tovar A, Smith GJ, Thomas JM, Crouse WL, Harkema JR, Kelada SNP.
Toxicol Sci. 2019 Oct 18. pii: kfz219. doi: 10.1093/toxsci/kfz219. [Epub ahead of print]
PMID: 31626304

 

Immune predictors of mortality following RNA virus infection.
Graham JB, Swarts JL, Menachery VD, Gralinski LE, Schäfer A, Plante KS, Morrison CR, Voss KM, Green R, Choonoo G, Jeng S, Miller DR, Mooney MA, McWeeney SK, Ferris MT, Pardo-Manuel de Villena F, Gale M, Heise MT, Baric RS, Lund JM.
J Infect Dis. 2019 Oct 17. pii: jiz531. doi: 10.1093/infdis/jiz531. [Epub ahead of print]
PMID: 31621854

 

A population-based family clustering study of tic-related obsessive-compulsive disorder.
Brander G, Kuja-Halkola R, Rosenqvist MA, Rück C, Serlachius E, Fernández de la Cruz L, Lichtenstein P, Crowley JJ, Larsson H, Mataix-Cols D.
Mol Psychiatry. 2019 Oct 15. doi: 10.1038/s41380-019-0532-z. [Epub ahead of print]
PMID: 31616041

 

E-Cigarette Exposure Delays Implantation and Causes Reduced Weight Gain in Female Offspring Exposed <i>In Utero</i>.
Wetendorf M, Randall LT, Lemma MT, Hurr SH, Pawlak JB, Tarran R, Doerschuk CM, Caron KM.
J Endocr Soc. 2019 Sep 5;3(10):1907-1916. doi: 10.1210/js.2019-00216. eCollection 2019 Oct 1.
PMID: 31598571

 

Clinical spectrum of individuals with pathogenic NF1 missense variants affecting p.Met1149, p.Arg1276 and p.Lys1423: genotype-phenotype study in neurofibromatosis type 1.
Koczkowska M, Callens T, Chen Y, Gomes A, Hicks AD, Sharp A, Johns E, Uhas KA, Armstrong L, Bosanko KA, Babovic-Vuksanovic D, Baker L, Basel DG, Bengala M, Bennett JT, Chambers C, Clarkson LK, Clementi M, Cortés FM, Cunningham M, D’Agostino MD, Delatycki MB, Digilio MC, Dosa L, Esposito S, Fox S, Freckmann ML, Fauth C, Giugliano T, Giustini S, Goetsch A, Goldberg Y, Greenwood RS, Griffis C, Gripp KW, Gupta P, Haan E, Hachen RK, Haygarth TL, Hernández-Chico C, Hodge K, Hopkin RJ, Hudgins L, Janssens S, Keller K, Kelly-Mancuso G, Kochhar A, Korf BR, Lewis AM, Liebelt J, Lichty A, Listernick RH, Lyons MJ, Maystadt I, Ojeda MM, McDougall C, McGregor LK, Melis D, Mendelsohn N, Nowaczyk MJM, Ortenberg J, Panzer K, Pappas JG, Pierpont ME, Piluso G, Pinna V, Pivnick EK, Pond DA, Powell CM, Rogers C, Shahar NR, Rutledge SL, Saletti V, Sandaradura SA, Santoro C, Schatz UA, Schreiber A, Scott DA, Sellars EA, Sheffer R, Siqveland E, Slopis JM, Smith R, Spalice A, Stockton DW, Streff H, Theos A, Tomlinson GE, Tran G, Trapane PL, Trevisson E, Ullrich NJ, Van den Ende J, Schrier Vergano SA, Wallace SE, Wangler MF, Weaver DD, Yohay KH, Zackai E, Zonana J, Zurcher V, Claes KBM, Eoli M, Martin Y, Wimmer K, De Luca A, Legius E, Messiaen LM.
Hum Mutat. 2019 Oct 8. doi: 10.1002/humu.23929. [Epub ahead of print]
PMID: 31595648

 

RNA Expression Profiling of Lymphoepithelioma-Like Carcinoma of the Bladder Reveals a Basal-like Molecular Subtype.
Manocha U, Kardos J, Selitsky S, Zhou M, Johnson SM, Breslauer C, Epstein JI, Kim WY, Wobker SE.
Am J Pathol. 2019 Oct 11. pii: S0002-9440(19)30755-2. doi: 10.1016/j.ajpath.2019.09.007. [Epub ahead of print]
PMID: 31610173

 

Centromeric SMC1 promotes centromer clustering and stabilizes meiotic homolog pairing.
Hatkevich T, Boudreau V, Rubin T, Maddox PS, Huynh JR, Sekelsky J.
PLoS Genet. 2019 Oct 14;15(10):e1008412. doi: 10.1371/journal.pgen.1008412. [Epub ahead of print]
PMID: 31609962