Department of Genetics faculty, postdocs, students and collaborators published 22 papers during September 15th – 28th, 2024.
Subramanian S, Geng H, Wu L, Du C, Peiper AM, Bu HF, Chou PM, Wang X, Tan SC, Iyer NR, Khan NH, Zechner EL, Fox JG, Breinbauer R, Qi C, Yamini B, Ting JP, De Plaen IG, Karst SM, Tan XD.
Cell Host Microbe. 2024 Sep 13:S1931-3128(24)00320-2. doi: 10.1016/j.chom.2024.08.013. Online ahead of print.
PMID: 39293437
Willems SM, Ng NHJ, Fernandez J, Fine RS, Wheeler E, Wessel J, Kitajima H, Marenne G, Sim X, Yaghootkar H, Wang S, Chen S, Chen Y, Chen YI, Grarup N, Li-Gao R, Varga TV, Asimit JL, Feng S, Strawbridge RJ, Kleinbrink EL, Ahluwalia TS, An P, Appel EV, Arking DE, Auvinen J, Bielak LF, Bihlmeyer NA, Bork-Jensen J, Brody JA, Campbell A, Chu AY, Davies G, Demirkan A, Floyd JS, Giulianini F, Guo X, Gustafsson S, Jackson AU, Jakobsdottir J, Järvelin MR, Jensen RA, Kanoni S, Keinanen-Kiukaanniemi S, Li M, Lu Y, Luan J, Manning AK, Marten J, Meidtner K, Mook-Kanamori DO, Muka T, Pistis G, Prins B, Rice KM, Sanna S, Smith AV, Smith JA, Southam L, Stringham HM, Tragante V, van der Laan SW, Warren HR, Yao J, Yiorkas AM, Zhang W, Zhao W, Graff M, Highland HM, Justice AE, Marouli E, Medina-Gomez C, Afaq S, Alhejily WA, Amin N, Asselbergs FW, Bonnycastle LL, Bots ML, Brandslund I, Chen J, Danesh J, de Mutsert R, Dehghan A, Ebeling T, Elliott P; EPIC-Interact Consortium; Farmaki AE, Faul JD, Franks PW, Franks S, Fritsche A, Gjesing AP, Goodarzi MO, Gudnason V, Hallmans G, Harris TB, Herzig KH, Hivert MF, Jørgensen T, Jørgensen ME, Jousilahti P, Kajantie E, Karaleftheri M, Kardia SLR, Kinnunen L, Koistinen HA, Komulainen P, Kovacs P, Kuusisto J, Laakso M, Lange LA, Launer LJ, Leong A, Lindström J, Manning Fox JE, Männistö S, Maruthur NM, Moilanen L, Mulas A, Nalls MA, Neville M, Pankow JS, Pattie A, Petersen ERB, Puolijoki H, Rasheed A, Redmond P, Renström F, Roden M, Saleheen D, Saltevo J, Savonen K, Sebert S, Skaaby T, Small KS, Stančáková A, Stokholm J, Strauch K, Tai ES, Taylor KD, Thuesen BH, Tönjes A, Tsafantakis E, Tuomi T, Tuomilehto J; Understanding Society Scientific Group; Uusitupa M, Vääräsmäki M, Vaartjes I, Zoledziewska M, Abecasis G, Balkau B, Bisgaard H, Blakemore AI, Blüher M, Boeing H, Boerwinkle E, Bønnelykke K, Bottinger EP, Caulfield MJ, Chambers JC, Chasman DI, Cheng CY, Collins FS, Coresh J, Cucca F, de Borst GJ, Deary IJ, Dedoussis G, Deloukas P, den Ruijter HM, Dupuis J, Evans MK, Ferrannini E, Franco OH, Grallert H, Hansen T, Hattersley AT, Hayward C, Hirschhorn JN, Ikram A, Ingelsson E, Karpe F, Kaw KT, Kiess W, Kooner JS, Körner A, Lakka T, Langenberg C, Lind L, Lindgren CM, Linneberg A, Lipovich L, Liu CT, Liu J, Liu Y, Loos RJF, MacDonald PE, Mohlke KL, Morris AD, Munroe PB, Murray A, Padmanabhan S, Palmer CNA, Pasterkamp G, Pedersen O, Peyser PA, Polasek O, Porteous D, Province MA, Psaty BM, Rauramaa R, Ridker PM, Rolandsson O, Rorsman P, Rosendaal FR, Rudan I, Salomaa V, Schulze MB, Sladek R, Smith BH, Spector TD, Starr JM, Stumvoll M, van Duijn CM, Walker M, Wareham NJ, Weir DR, Wilson JG, Wong TY, Zeggini E, Zonderman AB, Rotter JI, Morris AP, Boehnke M, Florez JC, McCarthy MI, Meigs JB, Mahajan A, Scott RA, Gloyn AL, Barroso I.
Wellcome Open Res. 2023 Oct 20;8:483. doi: 10.12688/wellcomeopenres.18754.1. eCollection 2023.
PMID: 39280063 Free PMC article.
Ong HW, Yang X, Smith JL, Taft-Benz S, Howell S, Dickmander RJ, Havener TM, Sanders MK, Brown JW, Couñago RM, Chang E, Krämer A, Moorman NJ, Heise M, Axtman AD, Drewry DH, Willson TM.
Molecules. 2024 Sep 2;29(17):4158. doi: 10.3390/molecules29174158.
PMID: 39275006 Free PMC article.
Blanchard MW, Sigmon JS, Brennan J, Ahulamibe C, Allen ME, Ardery S, Baric RS, Bell TA, Farrington J, Ciavatta D, Cruz Cisneros MC, Drushal M, Ferris MT, Fry RC, Gaines C, Gu B, Heise MT, Hock P, Hodges RA, Hulgin M, Kafri T, Lynch RM, Magnuson T, Miller DR, Murphy CEY, Nguyen DT, Noll KE, Proulx MK, Sassetti CM, Schoenrock SA, Shaw GD, Simon JM, Smith CM, Styblo M, Tarantino LM, Woo J, Pardo Manuel de Villena F.
G3 (Bethesda). 2024 Sep 13:jkae193. doi: 10.1093/g3journal/jkae193. Online ahead of print.
PMID: 39271181
Pol-Fuster J, Fernández de la Cruz L, Beucke J, Hesselmark E, Crowley JJ, de Schipper E, Brikell I, Chang Z, D’Onofrio BM, Larsson H, Lichtenstein P, Kuja-Halkola R, Mataix-Cols D.
Biol Psychiatry. 2024 Sep 14:S0006-3223(24)01587-7. doi: 10.1016/j.biopsych.2024.09.004. Online ahead of print.
PMID: 39284402
Muenzer J, Amartino H, Burton BK, Scarpa M, Tylki-Szymańska A, Audi J, Botha J, Fertek D, Merberg D, Natarajan M, Whiteman DAH, Giugliani R.
Mol Genet Metab. 2024 Sep 10;143(1-2):108576. doi: 10.1016/j.ymgme.2024.108576. Online ahead of print.
PMID: 39303318
Fouks B, Miller KJ, Ross C, Jones C, Rueppell O.
Insect Mol Biol. 2024 Sep 19. doi: 10.1111/imb.12961. Online ahead of print.
PMID: 39297191
Estimation of Linear Functionals in High-Dimensional Linear Models: From Sparsity to Nonsparsity.
Zhao J, Zhou Y, Liu Y.
J Am Stat Assoc. 2024;119(546):1579-1591. doi: 10.1080/01621459.2023.2206084. Epub 2023 Jun 22.
PMID: 39296805
Oral SARS-CoV-2 host responses predict the early COVID-19 disease course.
Seaman WT, Keener O, Nanayakkara D, Mollan KR, Premkumar L, Cuadra EC, Jones CD, Pettifor A, Bowman NM; UNC OBSc Working Group; Wang F, Webster-Cyriaque J.
Sci Rep. 2024 Sep 18;14(1):21788. doi: 10.1038/s41598-024-67504-w.
PMID: 39294156 Free PMC article.
Epigenetic tuning of PD-1 expression improves exhausted T cell function and viral control.
Weiss SA, Huang AY, Fung ME, Martinez D, Chen ACY, LaSalle TJ, Miller BC, Scharer CD, Hegde M, Nguyen TH, Rowe JH, Osborn JF, Patterson DG, Sifnugel N, Mei-An Nolan C, Davidson RA, Schwartz MA, Bally APR, Neeld DK, LaFleur MW, Boss JM, Doench JG, Nicholas Haining W, Sharpe AH, Sen DR.
Nat Immunol. 2024 Sep 17. doi: 10.1038/s41590-024-01961-3. Online ahead of print.
PMID: 39289557
Jensen JL, Bobek O, Chan ICC, Miller BC, Hillman DW, Heller G, Druley T, Armstrong AJ, Morris MJ, Milowsky MI, Beltran H, Bolton KL, Coombs CC.
Clin Cancer Res. 2024 Sep 17:OF1-OF10. doi: 10.1158/1078-0432.CCR-24-0803. Online ahead of print.
PMID: 39287426
TNF Promoter Hypomethylation Is Associated With Mucosal Inflammation in IBD and Anti-TNF Response.
Levic DS, Niedzwiecki D, Kandakatla A, Karlovich NS, Juneja A, Park J, Stolarchuk C, Adams S, Willer JR, Schaner MR, Lian G, Beasley C, Marjoram L, Flynn AD, Valentine JF, Onken JE, Sheikh SZ, Davis EE, Evason KJ, Garman KS, Bagnat M.
Gastro Hep Adv. 2024 Jun 27;3(7):888-898. doi: 10.1016/j.gastha.2024.06.010. eCollection 2024.
PMID: 39286616 Free PMC article.
ON BLOCKWISE AND REFERENCE PANEL-BASED ESTIMATORS FOR GENETIC DATA PREDICTION IN HIGH DIMENSIONS.
Zhao B, Zheng S, Zhu H.
Ann Stat. 2024 Jun;52(3):948-965. doi: 10.1214/24-aos2378. Epub 2024 Aug 11.
PMID: 39281348
Differential prognostic value of residual nodal burden in breast cancer subtypes.
Thai CHNC, An SJ, Haase CR, Selfridge JM, Agala CB, Spanheimer PM.
Breast Cancer Res Treat. 2024 Sep 15. doi: 10.1007/s10549-024-07494-5. Online ahead of print.
PMID: 39278893
Shyr D, Dey R, Li X, Zhou H, Boerwinkle E, Buyske S, Daly M, Gibbs RA, Hall I, Matise T, Reeves C, Stitziel NO, Zody M, Neale BM, Lin X.
Am J Hum Genet. 2024 Sep 4:S0002-9297(24)00304-5. doi: 10.1016/j.ajhg.2024.08.018. Online ahead of print.
PMID: 39270648
Estrogen signaling suppresses tumor-associated tissue eosinophilia to promote breast tumor growth.
Artham S, Juras PK, Goyal A, Chakraborty P, Byemerwa J, Liu S, Wardell SE, Chakraborty B, Crowder D, Lim F, Strawser CH, Newlin M, Racioppi A, Dent S, Mirminachi B, Roper J, Perou CM, Chang CY, McDonnell DP.
Sci Adv. 2024 Sep 27;10(39):eadp2442. doi: 10.1126/sciadv.adp2442. Epub 2024 Sep 27.
PMID: 39331714
Barker MM, Kõiv K, Magnúsdóttir I, Milbourn H, Wang B, Du X, Murphy G, Herweijer E, Gísladóttir EU, Li H, Lovik A, Kähler AK, Campbell A, Feychting M, Hauksdóttir A, Joyce EE, Thordardottir EB, Frans EM, Hoffart A, Mägi R, Tómasson G, Ásbjörnsdóttir K, Jakobsdóttir J, Andreassen OA, Sullivan PF, Johnson SU, Aspelund T, Brandlistuen RE, Ask H, McCartney DL, Ebrahimi OV, Lehto K, Valdimarsdóttir UA, Nyberg F, Fang F.
Nat Commun. 2024 Sep 26;15(1):8124. doi: 10.1038/s41467-024-52342-1.
PMID: 39327436
Angelo F, Waltz M, Yan H, Berg JS, Foreman AKM, O’Daniel J, Rini C.
Genet Med. 2024 Sep 21:101279. doi: 10.1016/j.gim.2024.101279. Online ahead of print.
PMID: 39315524
Chen ZK, Quintanilla L, Su Y, Sheehy RN, Simon JM, Luo YJ, Li YD, Chen Z, Asrican B, Tart DS, Farmer WT, Ming GL, Song H, Song J.
Proc Natl Acad Sci U S A. 2024 Oct;121(40):e2405117121. doi: 10.1073/pnas.2405117121. Epub 2024 Sep 23.
PMID: 39312657
Agca Y, Amos-Landgraf J, Araiza R, Brennan J, Carlson C, Ciavatta D, Clary D, Franklin C, Korf I, Lutz C, Magnuson T, de Villena FP, Mirochnitchenko O, Patel S, Port D, Reinholdt L, Lloyd KCK.
Mamm Genome. 2024 Sep 20. doi: 10.1007/s00335-024-10070-3. Online ahead of print.
PMID: 39304538 Review.
Analysis of CNS autoimmunity in genetically diverse mice reveals unique phenotypes and mechanisms.
Nelson EA, Tyler AL, Lakusta-Wong T, Lahue KG, Hankes KC, Teuscher C, Lynch RM, Ferris MT, Mahoney JM, Krementsov DN.
JCI Insight. 2024 Sep 26:e184138. doi: 10.1172/jci.insight.184138. Online ahead of print.
PMID: 39325545
Tahir UA, Barber JL, Cruz DE, Kars ME, Deng S, Tuftin B, Gillman MG, Benson MD, Robbins JM, Chen ZZ, Rao P, Katz DH, Farrell L, Sofer T, Hall ME, Ekunwe L, Tracy RP, Durda P, Taylor KD, Liu Y, Johnson WC, Guo X, Chen YI, Manichaikul AW, Jain D, Wang TJ, Reiner AP, Natarajan P, Itan Y, Rich SS, Rotter JI, Wilson JG, Raffield LM, Gerszten RE.
J Clin Invest. 2024 Sep 24:e181802. doi: 10.1172/JCI181802. Online ahead of print.
PMID: 39316441