Research Interests
Keywords: Hi-C, Chromatin architecture, Neuropsychiatric disorders, Substance use disorder, Functional Genomics, Massively parallel reporter assay
We try to bridge the gap between genetic risk factors for psychiatric illnesses and neurobiological mechanisms by decoding the regulatory relationships of the non-coding genome. In particular, we implement Hi-C, a genome-wide chromosome conformation capture technique, to identify the folding principle of the genome in human brain. We then leverage this information to identify the functional impacts of the common variants associated with neuropsychiatric disorders.
Mentor Training:
- Bias 101
Training Program Affiliations:
- Bioinformatics and Computational Biology
- Genetics and Molecular Biology
- Neuroscience
- Pharmacology
Publications
Hyejung Won in UNC Genetics News
September 26, 2022
Department of Genetics Publications for September 11th – 24th, 2022
Department of Genetics faculty, postdocs, students and collaborators published 10 papers during September 11th - 24th, 2022.
July 25, 2022
Scientists Reveal Genetic Architecture Underlying Alcohol, Cigarette Abuse
UNC School of Medicine researchers led by Hyejung Won, PhD, Assistant Professor of Genetics, used a new kind of computational tool to parse the complicated genetics that put some people at higher risk of becoming addicted to alcohol, cigarettes, and likely other substances of abuse.
July 5, 2022
Department of Genetics Publications for June 19th – July 2nd, 2022
Department of Genetics faculty, postdocs, students and collaborators published 11 papers during June 19th – July 2nd, 2022.
June 19, 2022
Department of Genetics Publications for June 5th – 18th, 2022
Department of Genetics faculty, postdocs, students and collaborators published 16 papers during June 5th – 18th, 2022.
May 9, 2022
Department of Genetics Publications April 24th – May 7th, 2022
Department of Genetics faculty, postdocs, students and collaborators published 14 papers during April 24th – May 7th, 2022.
April 25, 2022
Department of Genetics Publications April 10th – 23rd, 2022
Department of Genetics faculty, postdocs, students and collaborators published 18 papers during April 10th – 23rd, 2022.
November 1, 2021
Highlighted Faculty: Hyejung Won, PhD, Assistant Professor
Dr. Hyejung Won was recruited to the Department of Genetics and the Neuroscience Center at UNC Chapel Hill in 2018. Her up-and-coming research program integrates innovative genomic approaches with basic neurobiology to develop a systematic understanding of psychiatric and neurodevelopmental disorders. Dr. Won’s scientific career began at KAIST in Daejeon, South Korea where she earned …
October 18, 2021
Department of Genetics Publications October 3rd – 16th 2021
Department of Genetics faculty, postdocs, students and collaborators published 11 papers during October 3rd – 16th 2021.
September 20, 2021
Department of Genetics Publications September 5th – 18th 2021
Department of Genetics faculty, postdocs, students and collaborators published 7 papers during September 5th – 18th 2021.
September 9, 2021
Won, Mohlke, Love awarded UM1 as part of the new IGVF consortium at NHGRI
Hyejung Won (PhD, Assistant Professor, Department of Genetics, Neuroscience Center), Karen Mohlke (PhD, Professor, Department of Genetics), and Mike Love (PhD, Assistant Professor, Department of Biostatistics, Department of Genetics), were awarded a 5-year $9.25 million UM1 grant from the National Human Genome Research Institute (NHGRI) titled “Systematic in vivo characterization of disease-associated regulatory variants”. The …
