Department of Genetics faculty, postdocs, students and collaborators published 39 papers during June 29th – August 2nd 2025.
Pan-cancer immune and stromal deconvolution predicts clinical outcomes and mutation profiles.
Bhinder B, Friedl V, Sethuraman S, Risso D, Chiotti KE, Mashl RJ, Ellrott KP, Lee JA, Wong CK, Gyan K, Deshpande A, Imielinski M, Bareja R, Stuart J, Peto M, Hoadley KA, Lazar AJ, Cherniack AD, Zhu J, Cao S, Rubin M, Wang W, Bathe OF, Robine N, Ding L, Laird PW, Zhou W, Shen H, Thorsson V, Yeh JJ, Bailey MH, Zhou DC, Peng XL, Goldman M, Li Y, Korkut A, Sahni N, Hayes DN, Mensah MKA, Felau I, Kemal A, Caesar-Johnson S, Demchok JA, Yang L, Ferguson ML, Tarnuzzer R, Wang Z, Zenklusen JC; Cancer Genome Atlas Analysis Network; Spellman P, Elemento O.
Sci Rep. 2025 Jul 4;15(1):23921. doi: 10.1038/s41598-025-09075-y.
PMID: 40615649
The Psychiatric Genomics Consortium: discoveries and directions.
Agrawal A, Bulik CM, Abebe DS, Andreassen OA, Atkinson EG, Choi KW, Corvin A, Davies HL, Davis LK, Docherty AR, Edenberg HJ, Franke B, Gelernter J, Giusti-Rodríguez P, Hettema JM, Hjerling-Leffler J, Huang H, Johnson EC, Lewis CM, Lu Y, Lynall ME, Martin J, McIntosh AM, Montalvo-Ortiz JL, Mullins N, Nievergelt CM, O’Connell KS, O’Donovan MC, Okewole A, Peterson RE, Posthuma D, Sebat J, Smoller JW, Sud R, Viswanath B, Walters JTR, Won H, Wray NR, Sullivan PF; Coordinating Committee of the Psychiatric Genomics Consortium.
Lancet Psychiatry. 2025 Jun 26:S2215-0366(25)00124-5. doi: 10.1016/S2215-0366(25)00124-5. Online ahead of print.
PMID: 40582370 Review.
Currin KW, Perrin HJ, Pandey GK, Alkhawaja AA, Vadlamudi S, Musser AE, Etheridge AS, Broadaway KA, Rosen JD, Varshney A, Chaudhry AS, Gallins PJ, Wright FA, Zhou YH, Parker SCJ, Raffield LM, Schuetz EG, Innocenti F, Mohlke KL.
Genome Res. 2025 Jul 1;35(7):1485-1502. doi: 10.1101/gr.279741.124.
PMID: 40393811
The Interplay of Ontogeny and Phylogeny at the Transcriptome Level of the Tetrapod Heart.
Cordero GA, Holloway AK, Friedrich T, Eme J, Eckalbar W, Kusumi K, Janzen FJ, Hicks JW, Conlon FL, Bruneau BG, Pollard KS.
J Exp Zool B Mol Dev Evol. 2025 Jul 3. doi: 10.1002/jez.b.23312. Online ahead of print.
PMID: 40605499
Unmet needs of adults living with mucopolysaccharidosis II: data from the Hunter Outcome Survey.
Muenzer J, Amartino H, Giugliani R, Harmatz P, Lin SP, Link B, Molter D, Ramaswami U, Scarpa M, Botha J, Audi J, Burton BK.
Orphanet J Rare Dis. 2025 Jul 1;20(1):319. doi: 10.1186/s13023-024-03464-8.
PMID: 40598289 Free PMC article.
Russ D, Fitzpatrick CR, Saha C, Law TF, Jones CD, Kliebenstein DJ, Dangl JL.
Nat Commun. 2025 Jul 1;16(1):5699. doi: 10.1038/s41467-025-61266-3.
PMID: 40593847 Free PMC article.
BAHCC1 binds H4K20me1 to facilitate the MCM complex loading and DNA replication.
Li D, Zhang ZM, Mei L, Yu Y, Guo Y, Mackintosh SG, Chen J, Allison DF, Kim A, Storey AJ, Edmondson RD, Byrum SD, Tackett AJ, Cai L, Cook JG, Song J, Wang GG.
Nat Commun. 2025 Jul 1;16(1):5502. doi: 10.1038/s41467-025-61284-1.
PMID: 40592879 Free PMC article.
Cell-Derived Epigenomic Markers of Chronic Stress Distinguish Breast Cancer Phenotypes.
Acharya A, Zannas AS.
Yale J Biol Med. 2025 Jun 30;98(2):147-157. doi: 10.59249/YYQN6894. eCollection 2025 Jun.
PMID: 40589942 Free PMC article.
Hurwitz E, Varley CD, Anzolone AJ, Madhira V, Olex AL, Sun J, Vaidya D, Fadul N, Islam JY, Jackson LE, Wilkins KJ, Butzin-Dozier Z, Li D, Safo SE, McMurry JA, Maheria P, Williams T, Hassan SA, Haendel MA, Patel RC; National Clinical Cohort Collaborative (N3C) Consortium.
JMIR Med Inform. 2025 Jul 11;13:e68143. doi: 10.2196/68143.
PMID: 40644699
Protein quantitative trait locus analysis in African American and non-Hispanic White individuals.
Cai Y, Johnson M, Haessler J, Molstad AJ, Hwang SJ, Joehanes R, Murabito JM, Tahir UA, Franceschini N, Gerszten RE, Sun W, Levy D, Raffield LM, Kooperberg C, Hsu L, Reiner AP.
Genome Biol. 2025 Jul 10;26(1):200. doi: 10.1186/s13059-025-03671-x.
PMID: 40640959
Identification of Direct-Acting nsP2 Helicase Inhibitors with Antialphaviral Activity.
Muthu Ramalingam B, Sears JD, Talbot KM, Su YN, Houliston S, Hossain MA, Davis-Gilbert ZW, Zhao C, Oh HJ, Brown PJ, Sanders MK, Moorman SR, Ojha D, Burdick JE, Law I, Morales NL, Martinez SA, Loppnau P, Garcia Perez J, Drobish AM, Morrison TE, Streblow ZJ, Streblow DN, Arrowsmith CH, Vargason A, Couñago RM, Halabelian L, Arnold JJ, Cameron CE, Moorman NJ, Heise MT, Willson TM.
J Med Chem. 2025 Jul 9. doi: 10.1021/acs.jmedchem.5c00635. Online ahead of print.
PMID: 40634283
Agrawal YN, Fernández-Martínez A, Gil-Gil M, Zielinski C, Ruiz-Borrego M, Ciruelos EM, Muñoz M, Margelí M, Bermejo B, Antón A, Kahan Z, Csöszi T, Alonso-Romero JL, García-Saenz JÁ, Sánchez-Rovira P, Álvarez E, Chacón JI, González-Santiago S, Rodríguez CA, Servitja S, Pfefferle AD, Herranz J, Liu Y, Carey LA, Romero-Camarero I, Caballero R, Guerrero-Zotano Á, Perou CM, Martín M.
JCO Precis Oncol. 2025 Jul;9:e2400937. doi: 10.1200/PO-24-00937. Epub 2025 Jul 9.
PMID: 40632974 Clinical Trial.
The host response to influenza infections in human lung and macrophages cell lines.
Aguilar C, Lambertz RLO, Heise M, Eulalio A, Schughart K.
BMC Genom Data. 2025 Jul 8;26(1):46. doi: 10.1186/s12863-025-01341-2.
PMID: 40629279 Free PMC article.
Lahue C, Wong E, Dalal A, Tan Lek Wen W, Ren S, Foo R, Wang Y, Rau CD.
Epigenetics. 2025 Dec;20(1):2524411. doi: 10.1080/15592294.2025.2524411. Epub 2025 Jul 7.
PMID: 40624825 Free PMC article.
Overexpression of TSG101 causes the development of adenosquamous mammary carcinoma.
Dennaoui R, Rädler PD, Wicker MN, Vistisen K, Ferraiuolo RM, Triplett AA, Shrestha H, Liner TA, Manthey KC, Rui H, Cardiff RD, Gunn TM, Perou CM, Wagner KU.
Breast Cancer Res. 2025 Jul 7;27(1):126. doi: 10.1186/s13058-025-02007-8.
PMID: 40624726 Free PMC article.
Exogenous Hormones, Tumor Intrinsic Subtypes, and Breast Cancer.
Le Cornet C, Jung AY, Behrens S, Middha P, Truong T, Jernström H, Bolla MK, Wang Q, Southey MC, Beane Freeman LE, Koutros S, Stone J, Rennert G, Shulman K, Aronson KJ, Murphy RA, Guénel P, Patel AV, Bodelon C, Teras LR, Shahi S, Lacey JV, Dossus L, Kaaks R, Holleczek B, Brenner H, Brauch H, Hoppe R, Czene K, Hall PFL, Mannermaa A, Wu AH, Obi N, Michailidou K, Panayiotidis MI, McLean C, Haiman CA, Augustinsson A, Zheng W, Shu XO, Perou CM, Troester MA, Van Alsten S, Eliassen AH, Abubakar M, Kraft P, Ahearn TU, Evans DG, Wolk A, Milne RL, Easton DF, Pharoah PDP, Schmidt MK, García-Closas M, Vachon CM, Fortner RT, Chang-Claude J.
JAMA Netw Open. 2025 Jul 1;8(7):e2519236. doi: 10.1001/jamanetworkopen.2025.19236.
PMID: 40622713 Free PMC article.
Leveraging generative AI to assist biocuration of medical actions for rare disease.
Niyonkuru E, Caufield JH, Carmody LC, Gargano MA, Toro S, Whetzel PL, Blau H, Soto Gomez M, Casiraghi E, Chimirri L, Reese JT, Valentini G, Haendel MA, Mungall CJ, Robinson PN.
Bioinform Adv. 2025 Jun 12;5(1):vbaf141. doi: 10.1093/bioadv/vbaf141. eCollection 2025.
PMID: 40621601 Free PMC article.
Villacampa G, Pascual T, Tarantino P, Cortés J, Perez-García J, Llombart-Cussac A, Conte P, Mancino M, Guarneri V, Dieci MV, Waks AG, Schettini F, Brasó-Maristany F, Griguolo G, de Castro BA, Reboredo C, Antolín S, Bueno-Muiño C, Echavarría I, López-Tarruella S, Massarrah T, Del Monte-Millán M, Martín M, Buckingham W, Parker JS, Vivancos A, Polyak K, Filho OM, Wolff AC, DeMichele A, Tung NM, Perou CM, Paré L, Villagrasa P, Prat A, Tolaney SM.
Lancet Oncol. 2025 Jul 14:S1470-2045(25)00276-1. doi: 10.1016/S1470-2045(25)00276-1. Online ahead of print.
PMID: 40675165
DNA Methylation Signatures of Cardiovascular Health Provide Insights Into Diseases.
Carbonneau M, Li Y, Qu Y, Zheng Y, Wood AC, Wang M, Liu C, Huan T, Joehanes R, Guo X, Yao J, Taylor KD, Tracy RP, Durda P, Liu Y, Johnson WC, Post WS, Blackwell T, Rotter JI, Rich SS, Redline S, Fornage M, Wang J, Ning H, Hou L, Lloyd-Jones D, Ferrier K, Min YI, Carson AP, Raffield LM, Teumer A, Grabe HJ, Völzke H, Nauck M, Dörr M, Domingo-Relloso A, Fretts A, Tellez-Plaza M, Cole SA, Navas-Acien A, Wang M, Murabito JM, Heard-Costa NL, Prescott B, Xanthakis V, Mozaffarian D, Levy D, Ma J.
Circulation. 2025 Jul 14:10.1161/CIRCULATIONAHA.124.073181. doi: 10.1161/CIRCULATIONAHA.124.073181. Online ahead of print.
PMID: 40654086
Genomic loci and molecular genetic mechanisms for hidradenitis suppurativa.
Broadaway KA, Sun Q, Edmiston SN, Currin KW, Vadlamudi S, Miller-Fleming TW, Shi Y, Fajgenbaum K, Melendez-Gonzalez M, Bui H, Blum FR, Westerkam L, Shams R, Mallela T, Levitt B, Lin L, Hao H, Memili A, Straub P, Zhou W, Harris KM, Martin A, Cox NJ, Liu Z, Thomas NE, Li Y, Mohlke KL, Sayed CJ.
Br J Dermatol. 2025 Jul 12:ljaf277. doi: 10.1093/bjd/ljaf277. Online ahead of print.
PMID: 40650879
Transdiagnostic links of reward processing in obsessive-compulsive disorder and depression.
Wagner KM, Cervin M, Cheng JSC, Arriaga J, Cruz VZ, Berrones D, Muñoz JS, Frederick RM, Anderberg JL, Núñez Bracho BE, Adorno VR, Fontenelle LF, Wiese AD, Crowley JJ, Storch EA; Latin American Trans-Ancestry Initiative for OCD genomics (LATINO); Brazilian Obsessive-Compulsive Spectrum Disorder Working Group (GTTOC).
J Affect Disord. 2025 Jul 15:119886. doi: 10.1016/j.jad.2025.119886. Online ahead of print.
PMID: 40675261
Surgeon Decision-Making: A Contemporary, Qualitative Analysis of Urologists.
Spratte BN, Poulos K, Reines K, Blalock S, Bennett AV, Gessner KH, Nielsen ME, Reuland DS, Basch E, Tan HJ; UNC Connected Health for Applications & Intervention (CHAI) Core.
J Am Coll Surg. 2025 Jul 21. doi: 10.1097/XCS.0000000000001498. Online ahead of print.
PMID: 40680091
Harris S, Vora NL.
Prenat Diagn. 2025 Jul 17. doi: 10.1002/pd.6849. Online ahead of print.
PMID: 40675929 Review.
A DEEP NEURAL NETWORK TWO-PART MODEL AND FEATURE IMPORTANCE TEST FOR SEMI-CONTINUOUS DATA.
Zou B, Mi X, Wan S, Wu D, Xenakis JG, Hu J, Zou F.
Ann Appl Stat. 2025 Jun;19(2):1314-1331. doi: 10.1214/25-aoas2013. Epub 2025 May 28.
PMID: 40667518 Free PMC article.
Evaluating the role of alveolar macrophages in tolerance to ozone.
Smith GJ, Nalesnik M, Immormino RM, Simon JM, Harkema JR, Mock JR, Moran TP, Kelada SNP.
Toxicol Sci. 2025 Jul 25:kfaf095. doi: 10.1093/toxsci/kfaf095. Online ahead of print.
PMID: 40711967
Gural B, Kirkland L, Hockett A, Sandroni P, Zhang J, Rosa-Garrido M, Swift SK, Chapski DJ, Flinn MA, O’Meara CC, Vondriska TM, Patterson M, Jensen BC, Rau CD.
PLoS Genet. 2025 Jul 24;21(7):e1011807. doi: 10.1371/journal.pgen.1011807. Online ahead of print.
PMID: 40705823
Lester SA, Abdelwahab SH, Randell SH, Kelada SNP.
Toxicol Sci. 2025 Jul 23:kfaf089. doi: 10.1093/toxsci/kfaf089. Online ahead of print.
PMID: 40700611
Advances in machine learning for ABCA4-related retinopathy: segmentation and phenotyping.
Shwetar YJ, Brooks BP, Jeffrey BG, Solomon BD, Haendel MA.
Int Ophthalmol. 2025 Jul 23;45(1):314. doi: 10.1007/s10792-025-03690-4.
PMID: 40699379 Free PMC article. Review.
Polygenic prediction of body mass index and obesity through the life course and across ancestries.
Smit RAJ, Wade KH, Hui Q, Arias JD, Yin X, Christiansen MR, Yengo L, Preuss MH, Nakabuye M, Rocheleau G, Graham SE, Buchanan VL, Chittoor G, Graff M, Guindo-Martínez M, Lu Y, Marouli E, Sakaue S, Spracklen CN, Vedantam S, Wilson EP, Chen SH, Ferreira T, Ji Y, Karaderi T, Lüll K, Machado M, Malden DE, Medina-Gomez C, Moore A, Rüeger S, Akiyama M, Allison MA, Alvarez M, Andersen MK, Appadurai V, Arbeeva L, Bartell E, Bhaskar S, Bielak LF, Bis JC, Bollepalli S, Bork-Jensen J, Bradfield JP, Bradford Y, Brandl C, Braund PS, Brody JA, Broeckel U, Burgdorf KS, Cade BE, Cai Q, Camarda S, Campbell A, Cañadas-Garre M, Chai JF, Chesi A, Choi SH, Christofidou P, Couture C, Cuellar-Partida G, Danning R, Degenhardt F, Delgado GE, Delitala A, Demirkan A, Deng X, Dietl A, Dimitriou M, Dimitrov L, Dorajoo R, Eichelmann F, Eliasen AU, Engmann JE, Erdos MR, Fairhurst-Hunter Z, Farmaki AE, Faul JD, Fernandez-Lopez JC, Forer L, Frank M, Freitag-Wolf S, Fritsche LG, Fuchsberger C, Galesloot TE, Gao Y, Geller F, Giannakopoulou O, Giulianini F, Gjesing AP, Goel A, Gordon SD, Gorski M, Grove J, Guo X, Gustafsson S, Haessler J, Hansen TF, Havulinna AS, Haworth SJ, Heard-Costa N, Hemerich D, Highland HM, Hindy G, Ho YL, Hofer E, Holliday E, Horn K, Hornsby WE, Hottenga JJ, Huang H, Huang J, Huerta-Chagoya A, Huo S, Hwang MY, Hwu CM, Iha H, Ikeda DD, Isono M, Jackson AU, Jansen IE, Jiang Y, Johansson I, Jonsson A, Jørgensen T, Kalafati IP, Kanai M, Kanoni S, Kårhus LL, Kasturiratne A, Katsuya T, Kawaguchi T, Kember RL, Kentistou KA, Kim D, Kim HN, Kim YJ, Kleber ME, Knol MJ, Kurbasic A, Lauzon M, Le P, Lea R, Lee JY, Lee WJ, Leonard HL, Li H, Li SA, Li X, Li X, Liang J, Lin H, Lin K, Liu J, Liu X, Lo KS, Long J, Lores-Motta L, Luan J, Lyssenko V, Lyytikäinen LP, Mahajan A, Malik MZ, Mamakou V, Mangino M, Manichaikul A, Marten J, Mattheisen M, McDaid AF, Mei Q, Meiselbach H, Melendez TL, Milaneschi Y, Miller JE, Millwood IY, Mishra PP, Mitchell RE, Møllehave LT, Mononen N, Mucha S, Munz M, Mykkänen J, Nakatochi M, Nardone GG, Nelson CP, Nethander M, Nho CW, Nielsen AA, Nolte IM, Nongmaithem SS, Noordam R, Ntalla I, Nutile T, Pandit A, Pauper M, Petersen ERB, Petersen LV, Piluso F, Polašek O, Poveda A, Pyarajan S, Raffield LM, Rakugi H, Ramirez J, Rasheed A, Raven D, Rayner NW, Riveros C, Rohde R, Ruggiero D, Ruotsalainen SE, Ryan KA, Sabater-Lleal M, Santin A, Saxena R, Scholz M, Shen B, Shi J, Shin JH, Sidore C, Sidorenko J, Sim X, Slieker RC, Smith AV, Smith JA, Smyth LJ, Southam L, Steinthorsdottir V, Sun L, Takeuchi F, Taylor KD, Tayo BO, Tcheandjieu C, Terzikhan N, Tesolin P, Teumer A, Theusch E, Thompson DJ, Thorleifsson G, Timmers PRHJ, Trompet S, Turman C, Vaccargiu S, van der Laan SW, van der Most PJ, van Klinken JB, van Setten J, Verma SS, Verweij N, Veturi Y, Wang CA, Wang C, Wang JS, Wang L, Wang YX, Wang Z, Warren HR, Bin Wei W, Wen W, Wheeler WA, Wickremasinghe AR, Wielscher M, Winsvold BS, Wong A, Wuttke M, Xia R, Yamamoto K, Yang J, Yao J, Young H, Yousri NA, Yu L, Zeng L, Zhang W, Zhang X, Zhao JH, Zhao W, Zhou W, Zimmermann ME, Zoledziewska M, ‘t Hart LM, Adair LS, Adams HHH, Aguilar-Salinas CA, Al-Mulla F, Arnett DK, Asselbergs FW, Åsvold BO, Attia J, Banas B, Bandinelli S, Beilin LJ, Bennett DA, Bergler T, Bharadwaj D, Biino G, Boerwinkle E, Böger CA, Borja JB, Bouchard C, Bowden DW, Brandslund I, Brumpton B, Buring JE, Caulfield MJ, Chambers JC, Chandak GR, Chanock SJ, Chaturvedi N, Ida Chen YD, Chen Z, Cheng CY, Cho YS, Christensen K, Christophersen IE, Ciullo M, Cole JW, Collins FS, Concas MP, Cooper RS, Cruz M, Cucca F, Cutler MJ, Damrauer SM, Dantoft TM, de Borst GJ, de Geus EJC, de Groot LCPGM, De Jager PL, de Kleijn DPV, de Silva HJ, Dedoussis GV, den Hollander AI, Du S, Easton DF, Eckardt KU, Elders PJM, Eliassen AH, Ellinor PT, Elmståhl S, Erdmann J, Evans MK, Fatkin D, Feenstra B, Feitosa MF, Ferrucci L, Florez JC, Ford I, Fornage M, Franke A, Franks PW, Freedman BI, Gieger C, Girotto G, Golightly YM, Gonzalez-Villalpando C, Gordon-Larsen P, Grallert H, Grant SFA, Grarup N, Griffiths L, Gudnason V, Haiman C, Hakonarson H, Hansen T, Hartman CA, Hattersley AT, Hayward C, Heid IM, Heng CK, Hengstenberg C, Herzig KH, Hewitt AW, Hishigaki H, Hougaard DM, Hoyng CB, Huang PL, Huang W, Huang WY, Huffman JE, Hunt SC, Hutri N, Hveem K, Hyppönen E, Iacono WG, Ichihara S, Ikram MA, Isasi CR, Jarvelin MR, Jin ZB, Jöckel KH, Jonas JB, Joshi PK, Jousilahti P, Jukema JW, Kähönen M, Kamatani Y, Kang KD, Kaprio J, Kardia SLR, Karpe F, Kato N, Kavousi M, Kee F, Kessler T, Khera AV, Khor CC, Kiemeney LALM, Kim BJ, Kim EK, Kim HL, Kirchhof P, Kivimaki M, Koh WP, Koistinen HA, Kokkinos A, Kooner JS, Kooperberg C, Kovacs P, Kraaijeveld A, Kraft P, Krauss RM, Kumari M, Kutalik Z, Laakso M, Lange LA, Langenberg C, Launer LJ, Lee H, Lee NR, Lehtimäki T, Lemaitre RN, Li H, Li L, Lieb W, Lin X, Lind L, Linneberg A, Liu CT, Liu J, Loeffler M, London B, Lu F, Lubitz SA, Mackey DA, Magnusson PKE, Manson JE, Marcus GM, Marques Vidal P, Martin NG, März W, Matsuda F, McCarthy MI, McGarrah RW, McGue M, McKnight AJ, Medland SE, Mellström D, Metspalu A, Mitchell BD, Mitchell P, Mook-Kanamori DO, Mori TA, Morris AD, Mucci LA, Munroe PB, Nalls MA, Nazarian S, Nelson AE, Neville MJ, Newton-Cheh C, Nielsen CS, Niinikoski H, Nikus K, Nöthen MM, Ogunniyi A, Ohlsson C, Oldehinkel AJ, Orozco L, Pahkala K, Pajukanta P, Palmer CNA, Parra EJ, Pattaro C, Pedersen O, Pennell CE, Penninx BWJH, Perusse L, Peters A, Peyser PA, Porteous DJ, Posthuma D, Power C, Pramstaller PP, Province MA, Psaty BM, Qi Q, Qu J, Rader DJ, Raitakari OT, Rallidis LS, Rao DC, Redline S, Reilly DF, Reiner AP, Rhee SY, Ridker PM, Rienstra M, Ripatti S, Ritchie MD, Rivadeneira F, Roden DM, Rosendaal FR, Rotter JI, Rudan I, Rutters F, Ryu S, Sabanayagam C, Salako B, Saleheen D, Salomaa V, Samani NJ, Sanghera DK, Sattar N, Schmidt B, Schmidt H, Schmidt R, Schulze MB, Schunkert H, Scott LJ, Scott RJ, Sever P, Sheu WHH, Shoemaker MB, Shu XO, Simonsick EM, Sims M, Singleton AB, Sinner MF, Smith JG, Snieder H, Spector TD, Spedicati B, Stampfer MJ, Stark KJ, Strachan DP, Tabara Y, Tai ES, Tang H, Tardif JC, Thanaraj TA, Tönjes A, Tuomi T, Tuomilehto J, Tusié-Luna MT, van Dam RM, van der Harst P, Van der Velde N, van Duijn CM, van Schoor NM, Vitart V, Vohl MC, Völker U, Vollenweider P, Völzke H, Vrieze S, Wacher-Rodarte NH, Walker M, Wander GS, Wareham NJ, Watanabe RM, Watkins H, Weir DR, Werge TM, Widen E, Willemsen G, Willett WC, Wilson JF, Wilson PWF, Wong TY, Woo JT, Wright AF, Xu H, Yajnik CS, Yang J, Yokota M, Yuan JM, Zeggini E, Zemel BS, Zheng W, Zhu X, Zillikens MC, Zonderman AB, Zwart JA; 23andMe Research Team; DiscovEHR (DiscovEHR and MyCode Community Health Initiative); eMERGE (Electronic Medical Records and Genomics Network); GPC-UGR; PRACTICAL Consortium; Understanding Society Scientific Group; VA Million Veteran Program; Abecasis GR, Assimes TL, Auton A, Boehnke M, Chasman DI, Esko T, Stefansson K, Lettre G, Lindgren CM, Ng MCY, O’Donnell CJ, Thorsteinsdottir U, Visscher PM, Walters RG, Winkler TW, Wood AR, Deloukas P, Frayling TM, Justice AE, Kilpeläinen TO, Locke AE, Mohlke KL, North KE, Okada Y, Willer CJ, Young KL, Fatumo S, McCaffery JM, Timpson NJ, Hirschhorn JN, Sun YV, Berndt SI, Loos RJF.
Nat Med. 2025 Jul 21. doi: 10.1038/s41591-025-03827-z. Online ahead of print.
PMID: 40691366
Dickson A, Cone KR, Fortini BK, Goldstein J, Thompson ML, Wilke MVMB, Hurst ACE, Schroeder MC, Polonis K, Bowling KM.
J Mol Diagn. 2025 Jul 22:S1525-1578(25)00169-2. doi: 10.1016/j.jmoldx.2025.06.004. Online ahead of print.
PMID: 40706987
Racial differences in endometrial cancer genomics and outcomes using UNCseqTM targeted DNA sequencing.
Newton MA, Merker JD, Gong W, Patil S, Tan X, Cocoran DL, Pfefferle AD, Hayward MC, Broaddus R, Nichols HB, Olshan AF, Weissman B, Keku TO, Bae-Jump V.
Gynecol Oncol Rep. 2025 Jun 25;60:101795. doi: 10.1016/j.gore.2025.101795. eCollection 2025 Aug.
PMID: 40687919 Free PMC article.
Coordinated expression of retained introns and poison exons in renal cell carcinoma.
Martínez JC, Zhou M, Giri G, Tsai YH, Rowley MM, Goda GA, Aleman MM, Kim WY, Dominguez D.
Cell Rep. 2025 Jul 17;44(8):115985. doi: 10.1016/j.celrep.2025.115985. Online ahead of print.
PMID: 40682778
Predictors of Nodal Pathologic Complete Response After Neoadjuvant Chemotherapy in Breast Cancer.
An SJ, Thai CHNC, Agala CB, Abdou YG, Selfridge JM, Spanheimer PM.
Ann Surg Oncol. 2025 Jul 19. doi: 10.1245/s10434-025-17906-5. Online ahead of print.
PMID: 40684017
Tejwani V, Putcha N, Woo H, Liu C, Lafon D, Alexis NE, Azar A, Barr RG, Barjaktarevic I, Bowler RP, Comellas A, Couper DJ, Fawzy A, Han MK, Hansel NN, Kaner RJ, Krishnan JA, Marchetti N, Martinez FJ, Ohar J, O’Neal W, Ortega VE, Paine Iii R, Pottinger TD, Stämpfli M, Ruvuna L, Woodruff PG, Freeman CM, Huang YJ, Curtis JL.
Respir Res. 2025 Jul 18;26(1):250. doi: 10.1186/s12931-025-03310-w.
PMID: 40682114 Free PMC article.
Genome-wide Gene by Sleepiness Interaction Analysis for Sleep Apnea.