Department of Genetics Publications for November 24th – December 7th, 2024

Department of Genetics faculty, postdocs, students and collaborators published 17 papers during November 24th – December 7th, 2024.

Metabolism of inorganic arsenic in mice carrying the human AS3MT gene and fed folate deficient or folate supplemented diet. 

Miller M, Douillet C, Cable PH, Krupenko SA, Shang B, Hartwell HJ, Zou F, Koller BH, Fry RC, de Villena FP, Stýblo M.

Toxicol Appl Pharmacol. 2024 Nov 25:117173. doi: 10.1016/j.taap.2024.117173. Online ahead of print.

PMID: 39603428

 

Lethal COVID-19 associates with RAAS-induced inflammation for multiple organ damage including mediastinal lymph nodes. 

Topper MJ, Guarnieri JW, Haltom JA, Chadburn A, Cope H, Frere J, An J, Borczuk A, Sinha S, Kim J, Park J, Butler D, Meydan C, Foox J, Bram Y, Richard SA, Epsi NJ, Agan B, Chenoweth JG, Simons MP, Tribble D, Burgess T, Dalgard C, Heise MT, Moorman NJ, Baxter VK, Madden EA, Taft-Benz SA, Anderson EJ, Sanders WA, Dickmander RJ, Beigel K, Widjaja GA, Janssen KA, Lie T, Murdock DG, Angelin A, Soto Albrecht YE, Olali AZ, Cen Z, Dybas J, Priebe W, Emmett MR, Best SM, Kelsey Johnson M, Trovao NS, Clark KB, Zaksas V, Meller R, Grabham P, Schisler JC, Moraes-Vieira PM, Pollett S, Mason CE, Syrkin Wurtele E, Taylor D, Schwartz RE, Beheshti A, Wallace DC, Baylin SB.

Proc Natl Acad Sci U S A. 2024 Dec 3;121(49):e2401968121. doi: 10.1073/pnas.2401968121. Epub 2024 Nov 27.

PMID: 39602262

 

The Relationship of Duffy Gene Polymorphism with High-Sensitivity C-Reactive Protein, Mortality, and Cardiovascular Outcomes in Black Individuals. 

Ha ET, Haessler J, Taylor KD, Tuftin B, Briggs M, Parikh MA, Peterson SJ, Gerszten RE, Wilson JG, Kelsey K, Tahir UA, Seeman T, Rich SS, Carson AP, Post WS, Kooperberg C, Rotter JI, Raffield LM, Auer P, Reiner AP.

Genes (Basel). 2024 Oct 27;15(11):1382. doi: 10.3390/genes15111382.

PMID: 39596582 Free PMC article.

 

ARID1A governs the silencing of sex-linked transcription during male meiosis in the mouse. 

Menon DU, Chakraborty P, Murcia N, Magnuson T.

Elife. 2024 Nov 26;12:RP88024. doi: 10.7554/eLife.88024.

PMID: 39589400 Free PMC article.

 

Genomic analysis of global Mycobacterium abscessus isolates reveals ongoing evolution of drug-resistance-associated genes. 

Yang T, Beach KE, Zhu C, Gan M, Wang W, Zhou H, Peng L, Wang S, Cai L, Li W, Davis JB, Cicchetti N, Slechta ES, Barker A, Shakir SM, Carey AF, Liu Q.

J Infect Dis. 2024 Nov 26:jiae580. doi: 10.1093/infdis/jiae580. Online ahead of print.

PMID: 39589145

 

Meiotic Drive and Speciation. 

Searle JB, Pardo-Manuel de Villena F.

Annu Rev Genet. 2024 Nov;58(1):341-363. doi: 10.1146/annurev-genet-111523-102603.

PMID: 39585909 Review.

 

Timing of standard chow exposure determines the variability of mouse phenotypic outcomes and gut microbiota profile. 

Knuth MM, Campos CV, Smith K, Hutchins EK, Lewis S, York M, Coghill LM, Franklin C, MacFarlane AJ, Ericsson AC, Magnuson T, Ideraabdullah F.

Lab Anim (NY). 2024 Dec 5. doi: 10.1038/s41684-024-01477-1. Online ahead of print.

PMID: 39639104

 

Image analysis-based identification of high risk ER-positive, HER2-negative breast cancers. 

Lee DN, Li Y, Olsson LT, Hamilton AM, Calhoun BC, Hoadley KA, Marron JS, Troester MA.

Breast Cancer Res. 2024 Dec 4;26(1):177. doi: 10.1186/s13058-024-01915-5.

PMID: 39633505 Free PMC article.

 

Multimodal genome-wide survey of progressing and non-progressing breast ductal carcinoma in-situ. 

Debeljak M, Cho S, Downs BM, Considine M, Avin-McKelvey B, Wang Y, Perez PN, Grizzle WE, Hoadley KA, Lynch CF, Hernandez BY, van Diest PJ, Cozen W, Hamilton AS, Hawes D, Gabrielson E, Cimino-Mathews A, Florea LD, Cope L, Umbricht CB.

Breast Cancer Res. 2024 Dec 4;26(1):178. doi: 10.1186/s13058-024-01927-1.

PMID: 39633428 Free PMC article.

 

Concomitant loss of TET2 and TET3 results in T cell expansion and genomic instability in mice. 

Gioulbasani M, Äijö T, Liu S, Montgomery SA, Montgomery ND, Corcoran D, Tsagaratou A.

Commun Biol. 2024 Dec 3;7(1):1606. doi: 10.1038/s42003-024-07312-0.

PMID: 39627458 Free PMC article.

 

4-Substituted-2-Thiazole Amides as Viral Replication Inhibitors of Alphaviruses. 

Garzan A, Ahmed SK, Haese NN, Sulgey G, Medica S, Smith JL, Zhang S, Ahmad F, Karyakarte S, Rasmussen L, DeFilippis V, Tekwani B, Bostwick R, Suto MJ, Hirsch AJ, Morrison TE, Heise MT, Augelli-Szafran CE, Streblow DN, Pathak AK, Moukha-Chafiq O.

J Med Chem. 2024 Dec 2. doi: 10.1021/acs.jmedchem.4c01073. Online ahead of print.

PMID: 39621435

 

Metabolomics profiling in multi-ancestral individuals with type 2 diabetes in Singapore identified metabolites associated with renal function decline. 

Chen Y, Torta F, Koh HWL, Benke PI, Gurung RL, Liu JJ, Ang K, Shao YM, Chan GC, Choo JC, Ching J, Kovalik JP, Kalhan T, Dorajoo R, Khor CC, Li Y, Tang WE, Seah DEJ, Sabanayagam C, Sobota RM, Venkataraman K, Coffman T, Wenk MR, Sim X, Lim SC, Tai ES.

Diabetologia. 2024 Dec 2. doi: 10.1007/s00125-024-06324-z. Online ahead of print.

PMID: 39621102

 

Just a SNP away: The future of in vivo massively parallel reporter assay. 

Degner KN, Bell JL, Jones SD, Won H.

Cell Insight. 2024 Oct 10;4(1):100214. doi: 10.1016/j.cellin.2024.100214. eCollection 2025 Feb.

PMID: 39618480 Free PMC article. Review.

 

Paired analysis of host and pathogen genomes identifies determinants of human tuberculosis. 

Luo Y, Huang CC, Howard NC, Wang X, Liu Q, Li X, Zhu J, Amariuta T, Asgari S, Ishigaki K, Calderon R, Raman S, Ramnarine AK, Mayfield JA, Moody DB, Lecca L, Fortune SM, Murray MB, Raychaudhuri S.

Nat Commun. 2024 Nov 29;15(1):10393. doi: 10.1038/s41467-024-54741-w.

PMID: 39613754 Free PMC article.

 

Self-supervised graph contrastive learning with diffusion augmentation for functional MRI analysis and brain disorder detection. 

Wang X, Fang Y, Wang Q, Yap PT, Zhu H, Liu M.

Med Image Anal. 2024 Nov 29;101:103403. doi: 10.1016/j.media.2024.103403. Online ahead of print.

PMID: 39637557

 

Unequal Uptake: Insurance-Related Disparities in Prenatal Genetic Counseling and Screening at a Quaternary Medical Center. 

Mallampati D, Boynton M, Talati AN, Hardisty EL, Vora N.

Prenat Diagn. 2024 Nov 29. doi: 10.1002/pd.6713. Online ahead of print.

PMID: 39613980

 

Omission of Axillary Dissection in Node Positive Breast Cancer After Neoadjuvant Systemic Therapy. 

Peery GB, Pak J, Burkbauer L, Agala CB, Selfridge JM, Gallagher KK, Spanheimer PM.

J Surg Res. 2023 Dec;292:247-257. doi: 10.1016/j.jss.2023.08.004. Epub 2023 Sep 4.

PMID: 37660548 Free PMC article.