Research Interests
Keywords: Chromatin, epigenetics, transcription, cancer
We are interested in the links between epigenetics and gene regulation. Our primary focus is on understanding how changes to the composition of chromatin remodeling complexes are regulated, how their disruption affects their function, and contributes to disease. We focus on the SWI/SNF complex, which is mutated in 20% of all human tumors. This complex contains many variable subunits that can be assembled in combination to yield thousands of biochemically distinct complexes. We use a variety of computational and wet-lab techniques in cell culture and animal models to address these questions.
Mentor Training:
- Bias 101
- Faculty Mentoring Workshop for Biomedical Researchers
- REI Racial Equity Workshop Phase 1
Training Program Affiliations:
- Bioinformatics and Computational Biology
- Genetics and Molecular Biology
Publications
Jesse Raab in UNC Genetics News
July 27, 2022
Jesse Raab, PhD Awarded R35 Grant from NIGMS
Dr. Jesse Raab (Assistant Professor, Department of Genetics) has been awarded a five-year R35 grant from the National Institute of General Medical Sciences (NIGMS) for his project titled “Mechanisms of SWI/SNF complex assembly and function”.
February 9, 2022
Katie Hoadley, PhD and Jesse Raab, PhD Receive CEHS Pilot Award
Drs. Katie Hoadley and Jesse Raab (Assistant Professors, Genetics) received a Team Science Pilot Project Award from the UNC Center for Environmental Health and Susceptibility (CEHS) for their collaborative project titled “Understanding genetic and environmental drivers of primary liver cancer”.
February 8, 2021
Department of Genetics Publications for Jan. 24 – Feb. 6, 2021
Department of Genetics faculty, postdocs, students and collaborators published twenty papers during Jan. 24 – Feb. 6, 2021.
January 4, 2021
Department of Genetics Publications for December 13-26, 2020
Department of Genetics faculty, postdocs, students and collaborators published nine papers during Dec. 13-26, 2020.
July 7, 2020
Jesse Raab, PhD Awarded Grant from Department of Defense (DOD)
Dr. Raab (Assistant Professor, Genetics) was awarded a grant from the U.S. Army Medical Research Acquisition Activity (USAMRAA) for his project titled “Identification of New Therapeutic Strategies for Targeting Liver Fibrosis”.
January 15, 2020
Department of Genetics Welcomes Dr. Jesse Raab
Jesse Raab, PhD has been appointed as Assistant Professor on the tenure-track, effective January 1, 2020.
January 6, 2020
Department of Genetics Publications for Dec. 15-28, 2019
Department of Genetics faculty, postdocs, students and collaborators published eleven documents during Dec. 15-28, 2019.
April 18, 2019
Celebrating Funding Success for Early Stage Faculty
Over the past six months, multiple Assistant Professors in the department have been awarded grants to enable exploration of new fields of research and to support expansion of their programs.
March 4, 2019
Jesse Raab Receives Career Development Award from Department of Defense
Jesse Raab, PhD (Research Assistant Professor) is the PI on a new Career Development Award from DoD.
August 13, 2018
Department of Genetics Publications for July 29 – Aug. 11, 2018
Department of Genetics faculty, postdocs, students and collaborators published eleven papers during July 29 – Aug. 11, 2018.