Research Interests
Keywords: Computational Genomics, Bioinformatics, Cancer Biology, Genetics, Translational biology, RNA sequencing, TCGA
The Hoadley Lab is focused on understanding the biology of cancer through gene expression analyses and integrative genomic approaches. We have been long time members of The Cancer Genome Atlas (TCGA) project that has comprehensively characterized over 10,000 samples from 33 tumor types. UNC was one of the main RNA sequencing centers for the TCGA project and we participated in the gene expression analysis for many of these projects. Our group is continuing our collaborative work as a member of the NCI’s Center for Cancer Genomics new Genomic Data Analysis Network as a specialized center for RNA sequencing analysis. We will build on the experience developed in TCGA to analyze data for new NCI programs and collaborations such as the Exceptional Responders and ALCHEMIST. In addition, the group still focuses on breast cancer through projects to improve our classification of aggressive basal-like breast cancers and genomic analysis of clinical trials.
Mentor Training:
- Bias 101
- Faculty Mentoring Workshop for Biomedical Researchers
Training Program Affiliations:
- Bioinformatics and Computational Biology
- Genetics and Molecular Biology
Publications
Katie Hoadley in UNC Genetics News
October 18, 2021
Department of Genetics Publications October 3rd – 16th 2021
Department of Genetics faculty, postdocs, students and collaborators published 11 papers during October 3rd – 16th 2021.
October 14, 2021
Katie Hoadley, PhD Awarded New Grant as Part of Susan G. Komen Metastatic Breast Cancer Collaborative Research Initiative
Thanks to a $500,000 lead gift by Blue Cross and Blue Shield of North Carolina (Blue Cross NC), the Susan G. Komen and Blue Cross NC Metastatic Breast Cancer Disparities Collaborative Research Grant was awarded to a research team led by Jennifer Freedman, PhD, and Steven Patierno, PhD, of Duke Cancer Institute, and Katie Hoadley, PhD, of UNC Lineberger, who were awarded the grant to investigate how the ancestry of different populations impacts the immune response to metastatic breast cancer.
August 9, 2021
Department of Genetics Publications for July 25th – August 7th 2021
Department of Genetics faculty, postdocs, students and collaborators published 12 papers during July 25th – August 7th 2021.
June 28, 2021
Department of Genetics Publications for June 13-26, 2021
Department of Genetics faculty, postdocs, students and collaborators published twenty one papers during June 13-26, 2021.
April 23, 2021
Drs. Hoadley and Troester Awarded New R01 from NCI
Dr. Katherine Hoadley (Assistant Professor, Department of Genetics) is the PI of a new R01 grant from the National Cancer Institute (NCI) titled “P53, DNA repair imbalance, and immune response in breast cancer mortality disparities” (Dr. Melissa Troester, Lead PI).
March 8, 2021
Department of Genetics Publications for February 21 – March 6, 2021
Department of Genetics faculty, postdocs, students and collaborators published twelve papers during February 21 – March 6, 2021.
February 8, 2021
Department of Genetics Publications for Jan. 24 – Feb. 6, 2021
Department of Genetics faculty, postdocs, students and collaborators published twenty papers during Jan. 24 – Feb. 6, 2021.
January 25, 2021
Department of Genetics Publications for January 10-23, 2021
Department of Genetics faculty, postdocs, students and collaborators published seven papers during Jan. 10-23, 2021.
December 15, 2020
Hoadley leverages team science to generate critical breast cancer insights
For Katherine Hoadley, PhD, the best way to make progress and major scientific breakthroughs is by working as a team.
December 14, 2020
Department of Genetics Publications for Nov. 29 – Dec. 12, 2020
Department of Genetics faculty, postdocs, students and collaborators published ten papers during November 29 – December 12, 2020.
