Research Interests
Keywords: Computational Genomics, Bioinformatics, Cancer Biology, Genetics, Translational biology, RNA sequencing, TCGA
The Hoadley Lab is focused on understanding the biology of cancer through gene expression analyses and integrative genomic approaches. We have been long time members of The Cancer Genome Atlas (TCGA) project that has comprehensively characterized over 10,000 samples from 33 tumor types. UNC was one of the main RNA sequencing centers for the TCGA project and we participated in the gene expression analysis for many of these projects. Our group is continuing our collaborative work as a member of the NCI’s Center for Cancer Genomics new Genomic Data Analysis Network as a specialized center for RNA sequencing analysis. We will build on the experience developed in TCGA to analyze data for new NCI programs and collaborations such as the Exceptional Responders and ALCHEMIST. In addition, the group still focuses on breast cancer through projects to improve our classification of aggressive basal-like breast cancers and genomic analysis of clinical trials.
Mentor Training:
- Faculty Mentoring Workshop for Biomedical Researchers
Training Program Affiliations:
- Bioinformatics and Computational Biology
- Genetics and Molecular Biology
Publications
Katie Hoadley in UNC Genetics News

May 19, 2026
Hoadley Secures New Award from DoD
Dr. Katie Hoadley (Associate Professor, Genetics) received a new award from the Department of Defense for her project titled “Mapping histologic and molecular divergence in breast cancer metastasis”.

May 13, 2026
Department of Genetics Publications for April 2026
Department of Genetics faculty, postdocs, students and collaborators published 29 papers in April 2026.

May 12, 2026
Department of Genetics Publications for March 2026
Department of Genetics faculty, postdocs, students and collaborators published 35 papers in March 2026.

March 17, 2026
Department of Genetics Publications for February 2026
Department of Genetics faculty, postdocs, students and collaborators published 26 papers in February 2026.

February 26, 2026
Raab and Hoadley Labs publishes paper in G3
The laboratories of Jesse Raab and Katie Hoadley have published a new research article, “Hepatocyte-targeted Bap1 reduction in the liver primes an inflammatory transcriptional response,” in G3: Genes | Genomes | Genetics.

February 20, 2026
Department of Genetics Publications for January 2026
Department of Genetics faculty, postdocs, students and collaborators published 25 papers in January 2026.

December 16, 2025
Department of Genetics Publications for November 2025
Department of Genetics faculty, postdocs, students and collaborators published 29 papers in November 2025.

November 5, 2025
Department of Genetics Publications for October 2025
Department of Genetics faculty, postdocs, students and collaborators published 40 papers in October 2025.

August 8, 2025
Department of Genetics Publications for June 29th – August 2nd, 2025
Department of Genetics faculty, postdocs, students and collaborators published 39 papers during June 29th - August 2nd 2025.

May 9, 2025
Department of Genetics Publications for March 30th – April 26th, 2025
Department of Genetics faculty, postdocs, students and collaborators published 25 papers during March 30th - April 26th 2025.