Bailey Peck, a Genetics and Molecular Biology graduate student in Praveen Sethupathy’s lab, is first author of a collaborative paper, with Bioinformatics and Computational Biology grad student Matthew Weiser (Furey lab), Shehzad Sheikh, Assistant Professor of Medicine and Genetics (senior author), and Drs. Sethupathy and Furey as coauthors.
The article is available online in the journal Inflammatory Bowel Disease. The authors sequenced miRNAs from colon tissue obtained from patients with Crohn’s disease (CD) and controls. They found that patients with different subtypes of CD have characteristic patterns of expression for several miRNAs. These patterns may be useful as markers in guiding therapy. Additional coauthors include members of the UNC Center for Gastrointestinal Biology and Disease (CGIBD) and the Departments of Pathology/Laboratory Medicine and Surgery. The publication represents what will be an ongoing collaboration between the GI and Genetics communities in the UNC School of Medicine.