Drs. Jason Stein (Assistant Professor) and Hyejung Won (Assistant Professor) have been awarded an U01 grant from the National Institutes of Mental Health (NIMH) for their project titled “Discovery and validation of genetic variation impacting the gene regulatory landscape during human cortical development”.
Using a wide array of experimental approaches, they propose to identify genetic influences on two features of chromatin architecture (enhancer histone marks and interactions) during human cortical development in order to more completely explain regulatory mechanisms leading to risk for neuropsychiatric disorders.