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John C. Gomez, PhD

Research Associate

Selected Bibliography:

  1. McPeek MK, Gomez JC, Doerschuk CM. Neutrophils sing “IL[-10] be seeing you” in the lungs during pneumonia. J Leukoc Biol. 2024 Jan 5;115(1):1-3. doi: 10.1093/jleuko/qiad134. PMID: 37931143.
  2. Hagan RS, Gomez JC, Torres-Castillo J, Martin JR, Doerschuk CM. TBK1 is Required for Host Defense Functions Distinct from Type I IFN Expression and Myeloid Cell Recruitment in Murine S. pneumoniae pneumonia. Am J Respir Cell Mol Biol. 2022 Jun;66(6):671-681. doi: 10.1165/rcmb.2020-0311OC. PMID: 35358404. PMCID: PMC9163639.
  3. Gomez JC, Doerschuk CM. Hypoxia Can Make Neutrophils Hyper, Potentially Wreaking Havoc During Exacerbations in COPD. Am J Respir Crit Care Med. 2022 Apr 15;205(8):862-864. doi: 10.1164/rccm.202201-0086ED. PMID: 35148486. PMCID: PMC9838619.
  4. Gomez JC, Doerschuk CM. Neutrophil DREAM come true: The not-so-impossible quest for mechanisms of neutrophil function and heterogeneity. J Exp Med. 2022 Jan 3;219(1):e20212141. doi: 10.1084/jem.20212141. Erratum in: J Exp Med. 2022 Jan 3;219(1): PMID: 34910084; PMCID: PMC8679798.
  5. Mock JR, Dial CF, Tune MK, Norton DL, Martin JR, Gomez JC, Hagan RS, Dang H, Doerschuk CM. Transcriptional analysis of Foxp3+ Tregs and functions of two identified molecules during resolution of ALI. JCI Insight. 2019 Mar 21;4(6). doi: 10.1172/jci.insight.124958. PMID: 30753170. PMCID: PMC6482998.
  6. Engle ML, Monk JN, Jania CM, Martin JR, Gomez JC, Dang H, Parker JS, Doerschuk CM. Dynamic changes in lung responses after single and repeated exposures to cigarette smoke in mice. PLoS One. 2019 Feb 28;14(2):e0212866. doi: 10.1371/journal.pone.0212866. PMID: 30818335. PMCID: PMC6395068.
  7. Gomez JC, Dang H, Kanke M, Hagan RS, Mock JR, Kelada SNP, Sethupathy P, Doerschuk CM. Predicted effects of observed changes in the mRNA and microRNA transcriptome of lung neutrophils during S. pneumoniae pneumonia in mice. Sci Rep. 2017 Sep 12;7(1):11258. doi: 10.1038/s41598-017-11638-7. PMID: 28900269. PMCID: PMC5595893.
  8. Schick SF, Blount BC, Jacob P Rd, Saliba NA, Bernert JT, El Hellani A, Jatlow P, Pappas RS, Wang L, Foulds J, Ghosh A, Hecht SS, Gomez JC, Martin JR, Mesaros C, Srivastava S, St Helen G, Tarran R, Lorkiewicz PK, Blair IA, Kimmel HL, Doerschuk CM, Benowitz NL, Bhatnagar A. Biomarkers of exposure to new and emerging tobacco delivery products. Am J Physiol Lung Cell Mol Physiol. 2017 Sep 1;313(3):L425-L452. doi: 10.1152/ajplung.00343.2016. PMID: 28522563. PMCID: PMC5626373.
  9. Gomez JC, Doerschuk CM. Activating Integrins Isn’t Always “Beta” for Neutrophil Migration! Am J Respir Cell Mol Biol. 2017 May;56(5):561-562. doi: 10.1165/rcmb.2017-0066ED. PMID: 28459388. PMCID: PMC5449497.
  10. Gomez JC, Dang H, Martin JR, Doerschuk CM. Nrf2 Modulates Host Defense during Streptococcus pneumoniae Pneumonia in Mice. J Immunol. 2016 Oct 1;197(7):2864-79. doi: 10.4049/jimmunol.1600043. PMID: 27566827. PMCID: PMC5026972.
  11. Gomez JC, Yamada M, Martin JR, Dang H, Brickey WJ, Bergmeier W, Dinauer MC, Doerschuk CM. Mechanisms of interferon-γ production by neutrophils and its function during Streptococcus pneumoniae pneumonia. Am J Respir Cell Mol Biol. 2015 Mar;52(3):349-64. doi: 10.1165/rcmb.2013-0316OC. PMID: 25100610. PMCID: PMC4370257.
  12. Yamada M, Gomez JC, Chugh PE, Lowell CA, Dinauer MC, Dittmer DP, Doerschuk CM. Interferon-γ production by neutrophils during bacterial pneumonia in mice. Am J Respir Crit Care Med. 2011 May 15;183(10):1391-401. doi: 10.1164/rccm.201004-0592OC. PMID: 21169470. PMCID: PMC3114063.
  13. Gomez JC, Doerschuk CM. The role of CD18 in the production and release of neutrophils from the bone marrow. Lab Invest. 2010 Apr;90(4):599-610. doi: 10.1038/labinvest.2010.4. PMID: 20142805. PMCID: PMC4715461.
  14. Gomez JC, Soltys J, Okano K, Dinauer MC, Doerschuk CM. The role of Rac2 in regulating neutrophil production in the bone marrow and circulating neutrophil counts. Am J Pathol. 2008 Aug;173(2):507-17. doi: 10.2353/ajpath.2008.071059. PMID: 18583316. PMCID: PMC2475787.