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Marsico Lung Institute Publications for February 2026

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Marsico Lung Institute faculty, postdoc, student, and collaborator publications for February 2026 included papers appearing in the American Journal of Respiratory and Critical Care Medicine (with a cover image by Marsico’s Stephen Schworer, MD, PhD, et al), Journal of Neuroinflammation, and Annals of the American Thoracic Society. Check out the full list below:

  1. Fazio JC, Hong AW, Markovic D, Barr RG, Bleecker ER, Bowler RP, Couper DJ, Curtis JL, Drummond MB, Fortis S, Han MK, Kim V, Martinez FJ, Ohar J, Ortega VE, Barnes Iii R, Wells JM, Gandhi SA, Woodruff PG, Putcha N, Cooper CB, Tashkin DP, Buhr RG, Barjaktarevic I; SPIROMICS investigators. Exacerbations and Decreased Lung Function Predict Nebulizer Use and Uptake in COPD and Tobacco Exposed Persons With Preserved Spirometry. Chronic Obstr Pulm Dis. 2026 Feb 25. doi: 10.15326/jcopdf.2025.0714. Epub ahead of print. PMID: 41771268.
  2. Reese JT, Chimirri L, Bridges Y, Danis D, Caufield JH, Gargano MA, Kroll C, Schmeder A, Liu F, Wissink K, McMurry JA, Graefe ASL, Niyonkuru E, Korn DR, Casiraghi E, Valentini G, Jacobsen JOB, Haendel M, Smedley D, Mungall CJ, Robinson PN. Systematic benchmarking demonstrates large language models have not reached the diagnostic accuracy of traditional rare-disease decision support tools. Eur J Hum Genet. 2026 Feb 24. doi: 10.1038/s41431-026-02054-5. Epub ahead of print. PMID: 41735669.
  3. Tchuenkam PVK, White SJ, Potlapalli V, Keming EM, Muller MS, Kaunda DBN, Kharabora O, Dinglasan RR, Parr JB, Tume CB, Lin JT, Juliano JJ, Ali IM. Distribution of falciparum and non-falciparum malaria among symptomatic malaria patients in Dschang, West Region of Cameroon. PLoS One. 2026 Feb 24;21(2):e0340824. doi: 10.1371/journal.pone.0340824. PMID: 41734164; PMCID: PMC12931766.
  4. Koller BH, Nguyen M, Doedens JR, Harrison D, Clarke N, Watt AP, Gabel CA. CNS-targeted NLRP3 Inhibition by NT-0527 confers therapeutic advantage in a CAPS mouse model. J Neuroinflammation. 2026 Feb 21. doi: 10.1186/s12974-026-03731-4. Epub ahead of print. PMID: 41723527.
  5. Ghosh R, Fazal Z, Oler AJ, Tokita MJ, Lewis KL, Paul AJ, Schmitz EG, Saucier N, Yan J, Kamen M, Seifert BA, Klion AD, Khoury P, Delmonte OM, Notarangelo LD, Freeman AF, Zerbe CS, Uzel G, Metcalfe DD, Komarow HD, Carter MC, McDermott DH, Murphy PM, Olivier KN, Fuss I, Strober W, Rao VK, Bergerson JRE, Almeida de Jesus A, Goldbach-Mansky R, Al-Herz W, Holland SM, Cooper MA, Similuk MN, Walkiewicz MA; NIAID Centralized Sequencing Program. Clinical relevance of mosaic variants detected by exome sequencing. J Allergy Clin Immunol. 2026 Feb 20:S0091-6749(26)00092-8. doi: 10.1016/j.jaci.2026.02.011. Epub ahead of print. PMID: 41724404.
  6. Dickerson TA, Stack TJ, Benaim EH, O’Rourke S, McCain M, Thorp BD, Klatt-Cromwell C, Ebert CS Jr, Senior BA, Kimple AJ. Social Vulnerability and Quality of Life in Chronic Rhinosinusitis. Laryngoscope. 2026 Feb 18. doi: 10.1002/lary.70448. Epub ahead of print. PMID: 41708939.
  7. Denlinger LC, Israel E, Moore WC, Georas SN, Wright RJ, Castro M, Peden DB, Anstrom KJ, Bleecker ER, Alexander LC, Cahill KN, Cardet JC, Carr TF, Cedano J, Chen AY, Chupp GL, Comhair SAA, DiMango EA, Erzurum SC, Fahy JV, Fajt ML, Gaston BM, Jackson DJ, Jain S, Jarjour NN, Kenyon NJ, Kraft M, Krishnan JA, Kumar R, Lugogo NL, Martinez FD, Marquis MA, Pappalardo AA, Phipatanakul W, Rank MA, Rosenberg SR, Salciccioli JD, Sanchez M, Smith LJ, Sumino K, Szefler SJ, Tang M, Vijayanand P, Wechsler ME, Wenzel SE, White SR, Zeki AA, Ivanova A, Bacharier LB, Akuthota P; NHLBI PrecISE Study Team. PrecISE- A Biomarker Stratified Adaptive Trial of 5 Interventions in Severe Asthma: Final Protocol and the Baseline Cohort. J Allergy Clin Immunol. 2026 Feb 16:S0091-6749(26)00082-5. doi: 10.1016/j.jaci.2026.02.001. Epub ahead of print. PMID: 41707916.
  8. Wolber AR, McKay LS, Johnson RM, Hameed ZT, Mote KB, Julio SM, Cotter PA. Genetic evidence for a periplasmic protein as a third component for a subset of NtrYX family two-component systems. J Bacteriol. 2026 Feb 13:e0052125. doi: 10.1128/jb.00521-25. Epub ahead of print. PMID: 41685908.
  9. Elste J, Zanotti B, Schnurr M, Papanikolas MJ, Stephenson EJ, Swanson-Mungerson M, Volin MV, Freeman R, Tiwari V. Early Transcriptomic Response of Human Iris Stromal Cells During Herpes Simplex Virus Entry Reveals Interplay Between Cell Glycocalyx and Viral Exploitation. Int J Mol Sci. 2026 Feb 12;27(4):1771. doi: 10.3390/ijms27041771. PMID: 41751906; PMCID: PMC12940423.
  10. Putcha N, Bhatt SP, Bon J, Christenson SA, Han MK, Krishnan JA, Martinez FJ, Casaburi R, Crapo JD, Curtis JL, Diette GB, Dransfield MT, Eakin MN, Kalhan R, Mannino DM, Montes de Oca M, Musick H, Rowe SM, Smith BM, Salvi S, Soler X, Wedzicha JA, Wright JA, Woodruff PG, Wise RA, Chang V, Miller BE, Crim C, Drummond MB; American Thoracic Society Clinical Problems Assembly and the American Thoracic Society Drug/Device Discovery and Development Committee. Disease Modification and Progression in Pre-Chronic Obstructive Pulmonary Disease. An Official American Thoracic Society Workshop Report. Ann Am Thorac Soc. 2026 Feb 11:aaoag034. doi: 10.1093/annalsats/aaoag034. Epub ahead of print. PMID: 41671101.
  11. Burbank AJ, Owens J, Espaillat A, Atkinson CE, Schworer SA, Whaylen KM, Chason K, Hernandez ML. Remote data collection to detect asthma exacerbations: A decentralized approach to clinical research in asthma. J Clin Transl Sci. 2026 Feb 10;10(1):e35. doi: 10.1017/cts.2026.10697. PMID: 41788352; PMCID: PMC12957659.
  12. Wiener CA, Edmonds A, Sha BE, Stosor V, Barjaktarevic IZ, McCormack MC, Dionne JA, Alcaide ML, Cribbs SK, Gange SJ, Lazarous DG, Foronjy RF, Reddy DB, Huang L, Kunisaki KM, Morris A, Diggs AE, Ramirez C, Cole SR, Premkumar L, Floris-Moore MA, Drummond MB. Associations between serological evidence of SARS-CoV-2 infection and longitudinal pulmonary outcomes among people with HIV: analysis of the MACS/WIHS combined cohort study (MWCCS). Respir Res. 2026 Feb 5;27(1):119. doi: 10.1186/s12931-026-03542-4. PMID: 41639892; PMCID: PMC12964756.
  13. Comadoll E, Mascarella A, Straus-Takahashi M, Goralski JL. Early Transplacental Modulator Exposure Leading to Vas Deferens Preservation. Pediatr Pulmonol. 2026 Feb;61(2):e71495. doi: 10.1002/ppul.71495. PMID: 41642767.
  14. Kaji M, Asakura T, Yamada Y, Tanaka H, Namkoong H, Chubachi S, Yamada M, Ozawa T, Yokoyama Y, Iizuka S, Narita K, Nagao G, Kato R, Fukunaga N, Nakamura S, Azekawa S, Miyazaki S, Nakagawara K, Kamata H, Boucher RC, Fukunaga K, Hasegawa N, Jinzaki M. Quantitative airway evaluation using supine and upright computed tomography in patients with non-cystic fibrosis bronchiectasis and nontuberculous mycobacterial pulmonary disease. Eur J Radiol. 2026 Feb:195:112626. doi: 10.1016/j.ejrad.2025.112626. PMID: 41529418.
  15. Kesimer M, Radicioni G, Ford AA, Ceppe A, Alexis NE, Barr RG, Bleecker ER, Christenson SA, Cooper CB, Han MK, Hansel NN, Hastie AT, Hoffman EA, Kanner RE, Martinez FJ, Paine R, Woodruff PG, Boucher RC. A Quantitative Lung Mucin Score to Identify Chronic Bronchitis. NEJM Evid. 2026 Feb;5(2):EVIDoa2500051. doi: 10.1056/EVIDoa2500051. PMID: 41590989.
  16. Mirmozaffari Y, Roca C, Martin WJ, Heetderks KA, Van Dorsten A, Cook L, Benaim EH, Wolfgang MC, Kimple AJ. Species-Level Characterization of the Nasal Microbiome in Various Disease States Utilizing Third-Generation Sequencing. Int Forum Allergy Rhinol. 2026 Feb;16(2):129-131. doi: 10.1002/alr.70103. PMID: 41548201.
  17. O’Neal WK, Boucher RC. Molecular Echoes of Mucus Plugging in COPD. Am J Respir Crit Care Med. 2026 Feb;212(2):205–206. doi: 10.1093/ajrccm/aamaf101. PMID: 41738146.

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