Marsico Lung Institute Publications for October 2025

Marsico Lung Institute faculty, postdoc, student, and collaborator publications for October 2025 included papers appearing in Nature Nanotechnology, JAMA, and the American Journal of Respiratory and Critical Care Medicine. Check out the full list below:

1. Brocke SA, Smyth T, Dang H, Speen A, Kim YH, Christianson C, Kovalcik K, Pancras JP, Hays M, An Z, Wu W, Jaspers I. Seasonal PM2.5 exposures induce differential responses to influenza A virus infection in primary human airway epithelial cells. Part Fibre Toxicol. 2025 Oct 29;22(1):28. doi: 10.1186/s12989-025-00643-8. PMID: 41163199; PMCID: PMC12570438.
2. Leach TS, Albertson S, Clapp PW, Surendran V, Simon T, Donny EC, Walker SJ, Atala A, Murphy SV. Evaluation of Acute Exposure to Combustible and Novel Tobacco Products Using an In Vitro Human Airway Organ Tissue Equivalent Model. J Appl Toxicol. 2025 Oct 29. doi: 10.1002/jat.4971. Epub ahead of print. PMID: 41161322.
3. Muhlebach MS, Naehrlich L, Carr SB, Orenti A, Gambazza S; ECFS Patient Registry Steering Group. Changes in use of inhaled chronic antibiotics in the European CF population: an ECFS patient registry study. Respir Med. 2025 Oct 29:108465. doi: 10.1016/j.rmed.2025.108465. Epub ahead of print. PMID: 41173061.
4. Boucher RC. How far does the apple fall from the tree? Can J Respir Crit Care Sleep Med. 2025 Oct 24; 9:sup2, S27-S30. doi: 10.1080/24745332.2025.2483843.
5. Nalesnik M, Hickman E, Almond M, Herring L, Mordant AL, Mills AC, Payton A, Rager JE, Peden DB, Jaspers I, Alexis NE, Rebuli ME. Exploratory analysis of the impact of sex on sputum proteomic response to inhaled wood smoke in humans. Toxicol Sci. 2025 Oct 24:kfaf150. doi: 10.1093/toxsci/kfaf150. Epub ahead of print. PMID: 41134656.
6. Gao Y, Shi W, Klawa SJ, Daly ML, Samulski ET, Nazockdast E, Freeman R. Reversible metamorphosis of hierarchical DNA-inorganic crystals. Nat Nanotechnol. 2025 Oct 20. doi: 10.1038/s41565-025-02026-8. Epub ahead of print. PMID: 41116032.
7. Liu Q, Liu YJ, Liu R, Culviner PH, Wang X, Wolf ID, Chen K, Chen Y, Xiao Y, Zhang G, Sun R, Wakabayashi S, Howard NC, Gan M, Rubin EJ, Fortune SM, Zhu J. High-throughput cytological profiling uncovers genotype-phenotype associations in Mycobacterium tuberculosis clinical isolates. mSystems. 2025 Oct 9:e0097225. doi: 10.1128/msystems.00972-25. Epub ahead of print. PMID: 41065399.
8. Song D, Sood AK, Schworer SA, Iweala OI, Kwan M. Using Biologics in the Prevention of Anaphylaxis. Curr Allergy Asthma Rep. 2025 Oct 9;25(1):44. doi: 10.1007/s11882-025-01224-7. PMID: 41065919.
9. Cholon DM, Aleksandrov LA, Quinney NL, Boyles SE, Jensen TJ, Aleksandrov AA, Gentzsch M. Implications for cystic fibrosis therapy: Potentiator icenticaftor is superior to ivacaftor in improving function and maintaining stability of F508del CFTR. Sci Prog. 2025 Oct-Dec;108(4):368504251384892. doi: 10.1177/00368504251384892. Epub 2025 Oct 7. PMID: 41055920. PMCID: PMC12508541.
10. Rojas-Quintero J, Faner R, Chiu CY, Kue JT, Zhang Y, Sanz Rubio D, Colborg AS, Jakwerth CA, Schmidt-Weber CB, Maitland-van der Zee AH, Abdel-Aziz MI, Pilon AL, Owen CA, Plosa EJ, Kinney GL, Mc-Grath Morrow S, Gazzaneo MG, Cortes Santiago N, Lingappan K, Ledford J, Spence J, Sucre JM, Sauler M, Wu TD, Agusti A, Wheelock A, Illi S, von Mutius E, Bowler RP, Celli B, Abman SH, Wells JM, Polverino F; ALLIANCE study group, ECLIPSE and COPDGene investigators. Maternal Smoking and CC-16: Implications for Lung Development and COPD Across the Lifespan. Am J Respir Crit Care Med. 2025 Oct 7. doi: 10.1164/rccm.202504-0854OC. Epub ahead of print. PMID: 41056135.
11. Vasilevsky NA, Toro S, Matentzoglu N, Flack JE, Mullen KR, Hegde H, Gehrke S, Whetzel PL, Shwetar Y, Harris NL, Ngu MS, Alyea GL, Kane MS, Roncaglia P, Sid E, Thaxton CL, Wood V, Abraham RS, Achatz MI, Ajuyah P, Amberger JS, Babb L, Baker J, Balhoff JP, Berg JS, Bhalla A, Bofill-De Ros X, Braun IR, Broeren EC, Byer BK, Byrne AB, Callahan TJ, Carmody LC, Chan LE, Clause AR, Cohen JS, DeLuca M, Deuitch NT, Flowers M, Fraser J, Fujiwara T, Gitau V, Goldstein JL, Gration D, Groza T, Gyori BM, Hankey W, Hilton JA, Himmelstein DS, Hong SS, Hoyt CT, Huether R, Hurwitz E, Jacobsen JOB, Kikuchi A, Köhler S, Korn DR, Lagorce D, Laraway BJ, Li JY, Malheiro AJ, McLaughlin J, Meldal BHM, Mohan S, Moxon SAT, Munoz-Torres MC, Nelson TH, Nicholas FW, Ochoa D, Olson D, Oprea TI, Oskotsky TT, Osumi-Sutherland D, Paris K, Parkinson HE, Pendlington ZM, Peng XP, Pizzino A, Plon SE, Powell BC, Ratliff JC, Rehm HL, Remennik L, Riggs ER, Roberts S, Robinson PN, Ross JE, Schaper K, Schilder BM, Schmidt JL, Sharp EW, Similuk MN, Smedley D, Sneddon TP, Sparks R, Stefancsik R, Stupp GS, Sundar S, Takatsuki T, Tammen I, Tshering KC, Unni DR, Valasek E, Vanderver A, Wagner AH, Webb RF, Welter D, Yaya-Stupp D, Zankl A, Zhang XA, McMurry JA, Chute CG, Hamosh A, Mungall CJ, Haendel MA. Mondo: Integrating Disease Terminology Across Communities. Genetics. 2025 Oct 6:iyaf215. doi: 10.1093/genetics/iyaf215. Epub ahead of print. PMID: 41052288.
12. Wang Y, Deng Y, Chen J, Hahn Q, Umbaugh DS, Zhang Z, Zhang Y, Rowe SE, Li L, Herring LE, Conlon BP, Miao EA, Damania B, Diehl AM, Liu P. cGAS Inhibits ALDH2 to Suppress Lipid Droplet Function and Regulate MASLD Progression. Adv Sci (Weinh). 2025 Oct 3:e08576. doi: 10.1002/advs.202508576. Epub ahead of print. PMID: 41042077.
13. Chen Y, Xiang F, Hernandez ML, Carpenter D, Bozkurt A, Lobaton E. Robust Multimodal Cough Detection with Optimized Out-of-Distribution Detection for Wearables. IEEE J Biomed Health Inform. 2025 Oct 2;PP. doi: 10.1109/JBHI.2025.3616945. Epub ahead of print. PMID: 41037549.
14. Cardet JC, Chiarella SE, Hernandez ML. Management of Severe Refractory Asthma. JAMA. 2025 Oct 1. doi: 10.1001/jama.2025.14449. Epub ahead of print. PMID: 41032334.
15. Collins BF, Sundar KM, Gross JE, Carlos WG, Jamil SM. Heat Wave Risks for People with Lung Disease. Am J Respir Crit Care Med. 2025 Oct;211(10):P16-P17. doi: 10.1164/rccm.v211i10p16. PMID: 41004718. PMCID: PMC12553141.
16. Gentzsch M. Pulmonary Ionocytes at the Crossroads of Absorption and Secretion: Clues from the Ferret. Am J Respir Crit Care Med. 2025 Oct;211(10):1898-1900. doi: 10.1164/rccm.202508-2001ED. PMID: 40920899. PMCID: PMC12555049.
17. Leon-Astudillo C, Prero MY, Dy FJ, Kaslow J, Vo HH, Endres T, St Onge I, Phinizy P, Kumar K, Kirkby S, Perez IA, Gross JE, Okorie CUA. ATS Pediatric Core Curriculum 2024: The Role of the Pediatric Pulmonologist in the Intensive Care Unit. Pediatr Pulmonol. 2025 Oct;60(10):e71329. doi: 10.1002/ppul.71329. PMID: 41090280.
18. Raihan M, Markovetz M, Hill D, Song Y, Xuan X. Polymer solution flow transitions and scaling laws for changing contraction ratios in planar constriction microchannels. Soft Matter. 2025 Oct 1;21(38):7404-7419. doi: 10.1039/d5sm00688k. PMID: 40910481.
19. Schichlein KD, Masood S, Kim HH, Hawley BJ, Ghosh A, Samet JM, Porter NA, Smith GJ, Jaspers I. Aerosolized vitamin D attenuates ozone-induced inflammation and transcriptional responses via membrane antioxidant effects in human bronchial epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2025 Oct 1;329(4):L514-L523. doi: 10.1152/ajplung.00233.2025. Epub 2025 Sep 12. PMID: 40938902; PMCID: PMC12515420.