Marsico Lung Institute Publications for September 2025

Marsico Lung Institute faculty, postdoc, student, and collaborator publications for August 2025 included papers appearing in Cell, American Journal of Respiratory and Critical Care Medicine, and European Respiratory Journal. Check out the full list below:

1. Culviner PH, Frey AM, Liu Q, Ha DTM, Thai PVK, Thu DDA, Quang NL, Calderon R, Lecca L, Caws M, Dunstan SJ, Murray MB, Thuong NTT, Fortune SM. Evolution of Mycobacterium tuberculosis transcription regulation is associated with increased transmission and drug resistance. Cell. 2025 Sep 30:S0092-8674(25)01036-0. doi: 10.1016/j.cell.2025.09.005. Epub ahead of print. PMID: 41033311.
2. Dousa KM, Shin E, Kurz SG, Rubin EJ, Holland SM, Olivier KN, Daley CL, Kreiswirth BN, Pottinger PS, Bonomo RA. The Role of β-Lactam Antibiotics in Treating Mycobacterium abscessus: From Laboratory Insights to Clinical Applications and the Case for Clinical Trials. Clin Infect Dis. 2025 Sep 30:ciaf547. doi: 10.1093/cid/ciaf547. Epub ahead of print. PMID: 41026774.
3. Ghio AJ, Scott SA, Tilley SL. Particles exposures and sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2025 Sep 30;42(3):16384. doi: 10.36141/svdld.v42i3.16384. PMID: 41026019.
4. Jones BW, Rossi SL, Goralski JL, Martin SL. Associations between IPV and non-communicable diseases: a systematic review. BMC Public Health. 2025 Sep 30;25(1):3216. doi: 10.1186/s12889-025-24498-y. PMID: 41029655; PMCID: PMC12487615.
5. Tiruthani K, Card MP, Wolf W, Shen L, Schaefer A, Fritz M, Okuda K, Harkema JR, Mousa JJ, J Pickles R, Lai SK. Preferential apical infection and spread of human metapneumovirus highlights the importance of inhaled delivery of neutralizing monoclonal antibody to treat established infections. Proc Natl Acad Sci U S A. 2025 Sep 30;122(39):e2502897122. doi: 10.1073/pnas.2502897122. PMID: 40986358; PMCID: PMC12501197.
6. Putcha N, Maselli DJ, Bon J, Lester MG, Drummond MB. Dyspnea in Chronic Obstructive Pulmonary Disease: Expert Assessment of Management in Clinical Practice. Pulm Ther. 2025 Sep 27. doi: 10.1007/s41030-025-00318-x. Epub ahead of print. PMID: 41014472.
7. O’Neil ST, Schilder BM, Schaper K, Cox C, Korn D, Gehrke S, Mungall CJ, Haendel MA. monarchr: An R Package for Querying Biomedical Knowledge Graphs. Bioinformatics. 2025 Sep 26:btaf549. doi: 10.1093/bioinformatics/btaf549. Epub ahead of print. PMID: 41002262.
8. Kim MH, Luzum NA, Kimple AJ, Zemke AC, Frank-Ito D. Effects of Elexacaftor/Tezacaftor/Ivacaftor on the Sinonasal Airspace in Cystic Fibrosis. Laryngoscope. 2025 Sep 25. doi: 10.1002/lary.70156. Epub ahead of print. PMID: 40995952.
9. Schworer SA, Murano H, Dang H, Markovetz MR, Saito M, Kato T, Asakura T, Chen G, Gilmore RC, Morton LC, van Heusden C, Chua M, Strickler E, Wisniewski ZY, Crisp G, Mitchell E, Doherty KA, Mastan S, Trejo Bittar HE, Cody BA, Trudeau JB, De la Cruz G, Ralph LM, Askin FB, Panettieri RA Jr, Koziol-White CJ, Byrd KM, Livraghi-Butrico A, O’Neal WK, Randell SH, Wenzel SE, Okuda K, Boucher RC Jr. Airway Epithelial Heterogeneity and Mucus Plugging in Asthmatic Bronchioles. Am J Respir Crit Care Med. 2025 Sep 23. doi: 10.1164/rccm.202409-1849OC. Epub ahead of print. PMID: 40986379.
10. Gan M, Wang D, Li S, Wang Q, Liu Q. Ongoing evolution of PE/PPE genes in Mycobacterium tuberculosis associated with drug resistance and host immune response. mSystems. 2025 Sep 22:e0089825. doi: 10.1128/msystems.00898-25. Epub ahead of print. PMID: 40980874.
11. Bourassa MH, Sillon G, Ding S, Chioccioli M, Lek M, Ma K, Mejia-Garcia A, Gravel S, Vinh DC, Knowles MR, Leigh MW, Davis SD, Ferkol T, Olivier KN, Schecterman EN, Yin W, Sears PR, Gentzsch M, Boyles SE, Bennett WD, Zeman KL, Ostrowski LE, Zariwala MA, Shapiro AJ. ODAD4-Related Primary Ciliary Dyskinesia: Report of Five Cases and a Founder Variant in Quebec. Cells. 2025 Sep 18;14(18):1460. doi: 10.3390/cells14181460. PMID: 41002425; PMCID: PMC12468610.
12.  Wells JM, Titlestad IL, Tanash H, Turner AM, Chapman KR, Hatipoğlu UŞ, Goldklang MP, D’Armiento JM, Pirozzi CS, Drummond MB, Barjaktarevic IZ, Chatila WM, Devine MS, Strange C, Sandhaus RA, Parkin JM, Westfall E, Lin VY, Parks R, Kuo HC, Ekue A, Moffitt KL, Inshaw J, Aban I, Dransfield MT, Stockley RA. Two randomized controlled Phase 2 studies of the oral neutrophil elastase inhibitor alvelestat in alpha-1 antitrypsin deficiency. Eur Respir J. 2025 Sep 18:2501019. doi: 10.1183/13993003.01019-2025. Epub ahead of print. PMID: 40967767.
13. Smith AJ, Sears PR, Hennig M, Bhattacharjee RB, Yin W, Golliher H, Ishimaru D, Lombana TN, Lockhart DJ, Wustman BA, Ostrowski LE. Lipid Nanoparticle-encapsulated Dnai1 mRNA rescues ciliary activity in primary ciliary dyskinesia mouse cell models. J Cell Sci. 2025 Sep 17:jcs.264068. doi: 10.1242/jcs.264068. Epub ahead of print. PMID: 40963409.
14. Cunningham AR, Kimple AJ, Peach MS. Evaluating the Clarity of Retractions and the Spread of Misinformation in Otolaryngology. OTO Open. 2025 Sep 16;9(3):e70158. doi: 10.1002/oto2.70158. PMID: 40963880; PMCID: PMC12439187.
15. Preiss A, Bhatia A, Aragon LV, Baratta JM, Baskaran M, Blancero F, Brannock MD, Chew RF, Díaz I, Fitzgerald M, Kelly EP, Zhou AG, Carton TW, Chute CG, Haendel M, Moffitt R, Pfaff E; N3C Consortium and the RECOVER Cohort. Effect of Paxlovid treatment during acute COVID-19 on Long COVID onset: An EHR-based target trial emulation from the N3C and RECOVER consortia. PLoS Med. 2025 Sep 15;22(9):e1004711. doi: 10.1371/journal.pmed.1004711. PMID: 40953059; PMCID: PMC12445499.
16. Hoesterey DT, Dang H, Markovic D, Buhr RG, Tashkin DP, Barr RG, Belperio JA, Bowler RP, Bleecker ER, Couper DJ, Criner GG, Cooper CB, Doerschuk CM, Dransfield MT, Drummond MB, Fawzy A, Freeman CM, Han MK, Hansel NN, Hastie AT, Hoffman EA, Huang YJ, Kaner RJ, Kanner RE, Kim V, Krishnan JA, Martinez FJ, O’Neal WK, Ortega VE, Paine R 3rd, Shrivastav AK, Wells JM, Woodruff PG, Curtis JL, Barjaktarevic I. Neutrophil-to-Lymphocyte Ratio (NLR) as a Biomarker in Clinically Stable Chronic Obstructive Pulmonary Disease: SPIROMICS cohort. Ann Am Thorac Soc. 2025 Sep 8. doi: 10.1513/AnnalsATS.202412-1265OC. Epub ahead of print. PMID: 40920896.
17. Ostrowski LE, Abu-Nasser S, Zeman KL, Leigh MW, Zariwala MA, Olivier KN, Ferkol TW, Taylor CN, Ceppe AS, Knowles MR, Bennett WD. Mucociliary and cough clearance in primary ciliary dyskinesia as affected by mutations in RSPH1 or DNAH5. ERJ Open. 2025 Sep 4. doi: 10.1183/23120541.00681-2025.
18. Shwetar YJ, Haendel MA. Multidimensional Quantification of Macular Cone Activity in Pattern Electroretinography Using Discrete Wavelet Transform. Transl Vis Sci Technol. 2025 Sep 2;14(9):17. doi: 10.1167/tvst.14.9.17. PMID: 40938069; PMCID: PMC12439505.
19. Kinghorn B, Mollica F, Caudri D, Davis SD, Dell S, Ferkol TW, Gardner RA, Knowles MR, Milla C, Pittman JE, Rosenfeld M, Sagel SD, Shapiro AJ, Sullivan E, Sullivan KM, Tiddens HAWM, Zariwala MA, Leigh MW; Genetic Disorders of Mucociliary Clearance Consortium. Airway Disease Progression on Chest Computed Tomography in Children With Primary Ciliary Dyskinesia. Pediatr Pulmonol. 2025 Sep;60(9):e71287. doi: 10.1002/ppul.71287. PMID: 40965845.
20. Sundar KM, Collins BF, Gross JE, Carlos WG, Jamil SM. The growing health burden of heat waves with focus on respiratory effects. Am J Respir Crit Care Med. 2025 Sep;211(9):P13-P15. doi: 10.1164/rccm.v211i9p13. PMID: 40879356. PMCID: PMC12432394.