Category: Research News
Ascertaining Framingham Heart Failure Phenotype From Inpatient Electronic Health Record Data Using Natural Language Processing: a Multicentre Atherosclerosis Risk in Communities (ARIC) Validation Study
Carlton Moore, MD, MS Carlton Moore, MD, professor of medicine in the division of infectious diseases, is first author of a retrospective observational study design of patients hospitalized in 2015 from four hospitals participating in the Atherosclerosis Risk in Communities (ARIC) study. Using free-text clinical notes and reports from hospitalized patients, the study team wanted … Read more
Evaluation and Management of Heart Block After Transcatheter Aortic Valve Replacement
Anthony Mazzella, MD UNC Cardiology Fellow Anthony Mazzella, MD, is first author of a paper published in Cardiac Failure Review. Transcatheter aortic valve replacement (TAVR) has developed substantially since its inception. Improvements in valve design, valve deployment technologies, preprocedural imaging and increased operator experience have led to a gradual decline in length o … Read more
Emerging Therapies For AML With Myelodysplasia-Related Changes: Slowly But Surely Moving the Needle
David Phillips, MD, and Josh Zeidner, MD Patients with acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) have historically poor outcomes with conventional chemotherapy regimens. Davis Phillips, MD, internal medicine resident, and Josh Zeidner, MD, associate professor of medicine in the division of hematology, published an article that reviews the data for exist … Read more
Study Finds Bamlanivimab Reduces Risk of COVID in Skilled Nursing Homes and Assisted Living Facilities
Myron Cohen, MD Myron Cohen, MD, is the lead investigator of a study recently published in the Journal of the American Medical Association (JAMA) that shows bamlanivimab monotherapy reduced the incidence of infection in skilled nursing homes and assisted living facilities with high risk of SARS-CoV-2 exposure. The randomized phase 3 clinical trial included 966 residents and staff … Read more
What’s Best for Diabetes After Metformin?
John Buse, MD Results of the five-year GRADE trial, designed to understand the best second-line agent for patients with type 2 diabetes already taking metformin, were reported at the virtual American Diabetes Association (ADA) 81st Scientific Sessions and published in Medscape Medical News. Researchers found the injectable drugs Lantus (glargine) and Victoza (liraglutide) outperf … Read more
Trial Results Show Two Medications Most Effective in Lowering Blood Glucose Levels in Type 2 Diabetes Patients
Sue Kirkman, MD Two medications, liraglutide and insulin, were better at keeping A1C (a measurement of average blood glucose) levels less than 7% in recent GRADE study. The UNC Diabetes Care Center, lead by site principal investigator Sue Kirkman, MD, professor of medicine, in the division of endocrinology and metabolism, was one of the 37 sites to be a part of this NIH-funded co … Read more
Donaldson, Goralski Research Highlighted By MRM
Scott Donaldson, MD, and Jennifer Goralski, MD Magnetic Resonance in Medicine (MRM) recently highlighted research by Scott Donaldson, MD, professor of medicine, and Jennifer Goralski, MD, assistant professor of medicine and pediatrics, from the division of pulmonary and critical care medicine. Their paper “Comparison of single breath hyperpolarized 129Xe MRI with dynamic 19F MRI … Read more
Two Medicine Scholars Named to Physician-Scientist Training Program
Klara Klein, MD, PhD, and Shetal Patel, MD, PhD Klara Klein, MD, PhD, a fellow in the division of endocrinology and metabolism, and Shetal Patel, MD, PhD, assistant professor of medicine in the division of oncology, have received physician-scientist awards to cultivate their careers as translational clinician scientists. As part of the Forward Together Strategic Plan, the UNC Sch … Read more
‘Nanodecoy’ Therapy Binds and Neutralizes SARS-CoV-2 Virus
Jason Lobo, MD NC State researchers led by Ke Cheng, PhD, created a therapeutic approach that mimics the receptor that the virus binds to and then traps the virus before it infect cells. The Department of Medicine’s Jason Lobo, MD, the Kimberly H. Tsamoutales Distinguished Term Professor of Medicine, Division of Pulmonary Diseases and Critical Care Medicine, is a co-author on the … Read more
Highlights From Resident Research Day
Kimberly Mounighan, MD, and Hillary Spangler, MD On May 19, the UNC Internal Medicine Residency Program held “Resident Research Day” for the 2020-2021 year. Given all of the virtual conferences over the past year, Resident Research Day was also primarily virtual, but selected residents presented their research projects during noon conference. Despite the incredibly busy clinical … Read more
Heart Awareness Month, Highlighting Cardiovascular Services and One Mission
Medicine’s cardiovascular specialists care for thousands of patients every year, in clinic and in hospital, focused on one mission–exceptional heart care for the people of North Carolina while advancing the science and clinical practice of cardiovascular medicine. Following is a look at service highlights. Women’s Heart Program Paula Miller, MD, Ellina Max, PharmD, and Julia Lew … Read more
Study Highlights Need For More QI Efforts to Reduce Unnecessary Blood Cultures in Routine SSTI Cases
Emily Sturkie, MD Physician researchers in the division of hospital medicine and the division of infectious diseases collaborated for the study “Frequency and yield of blood cultures for observation patients with skin and soft tissue infections,” published this month in the American Journal of Emergency Medicine. The study was designed to measure frequency and yield of blood cult … Read more