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AFFILIATIONS: Biochemistry & Biophysics, Pharmaceutical Sciences |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Biophysics, Chemical Biology, Molecular Biology, Structural Biology |
Saskia Neher |
| Clinical / Research Focus: Our lab seeks to better understand the maturation and regulation of a group of human lipases. We aim to uncover how these lipases properly fold and exit the ER, and how their activity is subsequently … Read more |
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AFFILIATIONS: Biochemistry & Biophysics, McAllister Heart Institute |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Bioinformatics, Cardiovascular Biology, Molecular Biology, Structural Biology |
Gary J. Pielak |
| Clinical / Research Focus: My graduate students and I use the formalism of equilibrium thermodynamics and the tools of molecular biology and biophysics to understand how nature designs proteins.,My graduate students and I use t … Read more |
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AFFILIATIONS: Biochemistry & Biophysics, Chemistry |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Biophysics, Cancer Biology, Computational Biology, Structural Biology |
Silvia B. Ramos, MD, MS, PhD |
| Clinical / Research Focus: The research in the Ramos lab is focused on RNA-binding proteins and their physiopathological roles in vivo. Dr. Ramos has a broad medical and biochemical background, with specific training and … Read more |
| Mentors: | Undergraduate Students, Medical Students |
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AFFILIATIONS: Biochemistry & Biophysics, Blood Research Center, Lineberger Cancer Center |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Cancer, Cell Biology, Cell Signaling, Computational Biology, Hematology, Physiology, Structural Biology, Translational Medicine |
Dale Ramsden |
| Clinical / Research Focus: The end joining pathway is a major means for repairing chromosome breaks in vertebrates. My lab is using cellular and cell-free models to learn how end joining works, and what happens when it doesn’t … Read more |
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AFFILIATIONS: Biochemistry & Biophysics, Lineberger Cancer Center, Toxicology |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Cancer Biology, Genetics, Molecular Biology |
Matt Redinbo, |
| Clinical / Research Focus: The Redinbo Laboratory examines dynamic cellular processes using structural, chemical, molecular and cell biology. Our goals are to discover new drugs and to elucidate molecular pathways essential to … Read more |
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AFFILIATIONS: Biochemistry & Biophysics, Bioinformatics & Computational Biology, Chemistry, Microbiology & Immunology |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Chemical Biology, Drug Discovery, Molecular Medicine, Structural Biology |
Aziz Sancar, MD, PhD |
| Clinical / Research Focus: We have three main areas of research focus: (1) Nucleotide excision repair: The only known mechanism for the removal of bulky DNA adducts in humans. (2) DNA damage checkpoints: Biochemical pathways t … Read more |
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AFFILIATIONS: Biochemistry & Biophysics, Lineberger Cancer Center, Toxicology |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Biophysics, Cancer Biology, Molecular Biology |
John Sondek, PhD |
| Clinical / Research Focus: Our laboratory studies signal transduction systems controlled by heterotrimeric G proteins as well as Ras-related GTPases using a variety of biophysical, biochemical and cellular techniques. Member of … Read more |
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AFFILIATIONS: Biochemistry & Biophysics, Bioinformatics & Computational Biology, Lineberger Cancer Center, Pharmacology |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Biophysics, Cancer Biology, Cell Signaling, Structural Biology |
Chrystal Starbird, PhD |
| Clinical / Research Focus: My lab studies the structural basis of receptor tyrosine kinase activation, with an initial focus on TAM receptors. Specifically, we are interested in understanding the role membrane lipids play in TA … Read more |
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AFFILIATIONS: Biochemistry & Biophysics, Lineberger Cancer Center |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Biophysics, Cancer Biology, Cell Signaling, Drug Discovery, Immunology, Pharmacology, Structural Biology |
Brian D. Strahl, PhD |
| Clinical / Research Focus: Eukaryotic genomes are packaged into the nuclei of cells through the actions of histone proteins. These proteins not only play a role in condensing the genome but are fundamental to establishing and m … Read more |
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AFFILIATIONS: Biochemistry & Biophysics |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Bioinformatics, Biophysics, Cancer Biology, Cell Biology, Cell Signaling, Chemical Biology, Computational Biology, Epigenetics and Chromatin Biology, Genetics, Genomics, HIV/AIDS, Microbiology, Microscopy, Molecular Biology, Organismal Biology, Stem Cells, Structural Biology |
Ron Swanstrom, PhD |
| Clinical / Research Focus: Our group uses the tools of molecular biology to study HIV pathogenesis and latency. We have specific interests in how the virus evolves to infect a new cell type, usually in the brain, to cause a dis … Read more |
David C. Williams Jr, MD, PhD |
| Clinical / Research Focus: We study epigenetic complexes involved in gene silencing using structural biology and biophysical techniques. The over-arching goal is to develop inhibitors of these complexes as molecular prob … Read more |
| Mentors: | Undergraduate Students, Medical Students, Graduate Students |
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AFFILIATIONS: Biochemistry & Biophysics, Lineberger Cancer Center, Pathology & Lab Medicine |
CLINICAL/RESEARCH INTERESTS: Biophysics, Cancer Biology, Chemical Biology, Drug Discovery, Epigenetics and Chromatin Biology, Structural Biology |






