Gregory Matera, PhD |
| Clinical / Research Focus: The research in our laboratory focuses on foundational mechanisms that regulate eukaryotic gene expression. In particular, we are interested in the roles played by RNAs and proteins in genetic … Read more |
| Mentors: | Undergraduate Students, Graduate Students |
Daniel McKay, PhD |
| Clinical / Research Focus: My laboratory studies the mechanisms of epigenetic gene regulation during development. |
| Mentors: | Undergraduate Students, Graduate Students |
Karen L. Mohlke, PhD |
| Clinical / Research Focus: We identify genetic variants that influence common human traits with complex inheritance patterns, and we examine the molecular and biological mechanisms of the identified variants and the genes they … Read more |
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AFFILIATIONS: Bioinformatics & Computational Biology, Genetics |
CLINICAL/RESEARCH INTERESTS: Bioinformatics, Cardiovascular Biology, Genetics, Genomics, Molecular Medicine |
Adam Palmer, PhD |
| Clinical / Research Focus: Combination cancer therapy Most types of cancer can be treated more effectively by combination therapy than by a single therapy. Many cancers can even be cured with combination therapy. We study the m … Read more |
Fernando Pardo-Manuel de Villena, PhD |
| Clinical / Research Focus: Non-Mendelian genetics including, meiotic drive, parent-of-orifin effects and allelic exclusion.,Non-Mendelian genetics including, meiotic drive, parent-of-orifin effects and allelic exclusion. |
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AFFILIATIONS: Bioinformatics & Computational Biology, Genetics |
CLINICAL/RESEARCH INTERESTS: Bioinformatics, Computational Biology, Developmental Biology, Genetics, Genomics, Organismal Biology |
Charles M. Perou, PhD |
| Clinical / Research Focus: The focus of my lab is to characterize the biological diversity of human tumors using genomics, genetics, and cell biology, and then to use this information to develop improved treatments that are spe … Read more |
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AFFILIATIONS: Bioinformatics & Computational Biology, Computational Medicine Program, Genetics, Lineberger Cancer Center, Pathology & Lab Medicine, Toxicology |
CLINICAL/RESEARCH INTERESTS: Bioinformatics, Cancer Biology, Genetics, Genomics, Translational Medicine |
Jeremy Purvis, PhD |
| Clinical / Research Focus: We study the behavior of individual cells with a specific focus on “irreversible” cell fate decisions such as apoptosis, senescence, and differentiation. Why do genetically identical cells choose diff … Read more |
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AFFILIATIONS: Bioinformatics & Computational Biology, Genetics |
CLINICAL/RESEARCH INTERESTS: Cancer Biology, Cell Signaling, Computational Biology, Molecular Biology, Systems Biology |
Matt Redinbo, |
| Clinical / Research Focus: The Redinbo Laboratory examines dynamic cellular processes using structural, chemical, molecular and cell biology. Our goals are to discover new drugs and to elucidate molecular pathways essential to … Read more |
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AFFILIATIONS: Biochemistry & Biophysics, Bioinformatics & Computational Biology, Chemistry, Microbiology & Immunology |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Chemical Biology, Drug Discovery, Molecular Medicine, Structural Biology |
Jack Snoeyink |
| Clinical / Research Focus: My primary research area is computational geometry, in which one studies the design and analysis of algorithms for geometric computation. Computational geometry finds application in problems from soli … Read more |
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AFFILIATIONS: Bioinformatics & Computational Biology |
CLINICAL/RESEARCH INTERESTS: Computational Biology, Structural Biology |
John Sondek, PhD |
| Clinical / Research Focus: Our laboratory studies signal transduction systems controlled by heterotrimeric G proteins as well as Ras-related GTPases using a variety of biophysical, biochemical and cellular techniques. Member of … Read more |
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AFFILIATIONS: Biochemistry & Biophysics, Bioinformatics & Computational Biology, Lineberger Cancer Center, Pharmacology |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Biophysics, Cancer Biology, Cell Signaling, Structural Biology |
Alexander Tropsha, PhD |
| Clinical / Research Focus: The major area of our research is Biomolecular Informatics, which implies understanding relationships between molecular structures (organic or macromolecular) and their properties (activity or functio … Read more |
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AFFILIATIONS: Bioinformatics & Computational Biology, Pharmaceutical Sciences, Toxicology |
CLINICAL/RESEARCH INTERESTS: Bioinformatics, Computational Biology, Molecular Medicine, Structural Biology, Toxicology |
William Valdar, PhD |
| Clinical / Research Focus: I run a statistical genetics laboratory interested the relationship between genes and complex disease. I have a particular focus on the use of genetically diverse experimental model organism po … Read more |
| Mentors: | Graduate Students |
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AFFILIATIONS: Bioinformatics & Computational Biology, Biostatistics, Computational Medicine Program, Genetics, Lineberger Cancer Center |
CLINICAL/RESEARCH INTERESTS: Bioinformatics |



