Michael Madden, PhD |
| Clinical / Research Focus: Exposure to ambient air particulate matter has been associated with increased human deaths and cardiopulmonary morbidity, such as lung infections and increased asthma symptoms. I am investigating so … Read more |
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AFFILIATIONS: Toxicology |
CLINICAL/RESEARCH INTERESTS: Physiology, Toxicology, Translational Medicine |
Nobuyo N. Maeda |
| Clinical / Research Focus: Our research is focused on the genetics and molecular pathology of complex multi-factorial conditions in humans – obesity, diabetes, hypercholesterolemia, insulin resistance, and hypertension. These … Read more |
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AFFILIATIONS: McAllister Heart Institute, Nutrition, Pathology & Lab Medicine, Toxicology |
CLINICAL/RESEARCH INTERESTS: Cardiovascular Biology, Genetics, Molecular Biology, Molecular Medicine, Pathology |
Shaun D. McCullough |
| Clinical / Research Focus: Dr. McCullough’s lab focuses around the role of the epigenetic elements as both a molecular mechanism mediating the effects of toxic exposures and as a biomarker for predicting susceptible populations … Read more |
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AFFILIATIONS: Center for Environmental Medicine, Asthma & Lung Biology (CEMALB), Toxicology |
CLINICAL/RESEARCH INTERESTS: Cardiovascular Biology, Cell Signaling, Molecular Biology, Toxicology, Translational Medicine |
Leena Nylander-French, PhD |
| Clinical / Research Focus: My research focuses on understanding the relationship between dermal and inhalation exposure and the effect of individual genetic differences on the function of enzymes that detoxify hazardous agents … Read more |
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AFFILIATIONS: Toxicology |
CLINICAL/RESEARCH INTERESTS: Computational Biology, Genetics, Toxicology |
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AFFILIATIONS: Pharmaceutical Sciences, Toxicology |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Biophysics, Cell Biology, Chemical Biology, Drug Discovery |
David B. Peden, MD, MS |
| Clinical / Research Focus: Translational and clinical research in environmental lung disease.,Translational and clinical research in environmental lung disease. |
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AFFILIATIONS: Center for Environmental Medicine, Asthma & Lung Biology (CEMALB), Microbiology & Immunology, Pediatrics, Toxicology |
CLINICAL/RESEARCH INTERESTS: Toxicology |
Charles M. Perou, PhD |
| Clinical / Research Focus: The focus of my lab is to characterize the biological diversity of human tumors using genomics, genetics, and cell biology, and then to use this information to develop improved treatments that are spe … Read more |
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AFFILIATIONS: Bioinformatics & Computational Biology, Computational Medicine Program, Genetics, Lineberger Cancer Center, Pathology & Lab Medicine, Toxicology |
CLINICAL/RESEARCH INTERESTS: Bioinformatics, Cancer Biology, Genetics, Genomics, Translational Medicine |
Dale Ramsden |
| Clinical / Research Focus: The end joining pathway is a major means for repairing chromosome breaks in vertebrates. My lab is using cellular and cell-free models to learn how end joining works, and what happens when it doesn’t … Read more |
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AFFILIATIONS: Biochemistry & Biophysics, Lineberger Cancer Center, Toxicology |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Cancer Biology, Genetics, Molecular Biology |
Scott Randell, PhD |
| Clinical / Research Focus: Lung and Airway Biology and Disease, Innate Immunity, Stem Cells, Gene and Cell Therapy, Infectious Diseases, Cystic Fibrosis, Primary Ciliary Dyskinesia, Head and Neck and Lung Cancer, Inhalation Tox … Read more |
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AFFILIATIONS: Cell Biology & Physiology, Department of Medicine (DOM), Lineberger Cancer Center, Marsico Lung Institute, Otolaryngology/Head & Neck Surgery, Toxicology |
CLINICAL/RESEARCH INTERESTS: Cancer Biology, Cell Biology, Cell Signaling, Gene Therapy, Pathogenesis & Infection, Physiology, Pulmonary, Regenerative Medicine, Stem Cells, Toxicology |
Meghan E. Rebuli, PhD |
| Clinical / Research Focus: Sex differences in respiratory immune response to environmental exposures including air pollution, wildfire smoke, and tobacco products. |
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AFFILIATIONS: Center for Environmental Medicine, Asthma & Lung Biology (CEMALB), Children's Research Institute, Pediatrics, Toxicology |
CLINICAL/RESEARCH INTERESTS: Health Equity, Immunology, Pediatrics, Pulmonary, Toxicology, Translational Medicine |
James M. Samet, PhD |
| Clinical / Research Focus: Our laboratory is focused on the cellular and molecular mechanisms that control inflammatory and adaptive responses induced by inhalation of ambient air pollutants. Projects focus on early events tha … Read more |
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AFFILIATIONS: Toxicology |
CLINICAL/RESEARCH INTERESTS: Immunology, Toxicology |
Aziz Sancar, MD, PhD |
| Clinical / Research Focus: We have three main areas of research focus: (1) Nucleotide excision repair: The only known mechanism for the removal of bulky DNA adducts in humans. (2) DNA damage checkpoints: Biochemical pathways t … Read more |
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AFFILIATIONS: Biochemistry & Biophysics, Lineberger Cancer Center, Toxicology |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Biophysics, Cancer Biology, Molecular Biology |



