Greg Scherrer, PharmD, PhD |
| Clinical / Research Focus: The primary mission of my laboratory is to elucidate the mechanisms that underlie pain perception and its modulation by opioids. We investigate the sensory, affective, and cognitive dimensions of pain … Read more |
John Sondek, PhD |
| Clinical / Research Focus: Our laboratory studies signal transduction systems controlled by heterotrimeric G proteins as well as Ras-related GTPases using a variety of biophysical, biochemical and cellular techniques. Member of … Read more |
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AFFILIATIONS: Biochemistry & Biophysics, Bioinformatics & Computational Biology, Lineberger Cancer Center, Pharmacology |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Biophysics, Cancer Biology, Cell Signaling, Structural Biology |
Philip Spanheimer, MD |
| Clinical / Research Focus: I am a surgical oncologist specializing in breast cancer and sarcoma. I try to bring a patient centered focus to the laboratory to understand disease processes and develop better treatments. Our lab h … Read more |
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AFFILIATIONS: Lineberger Cancer Center, Surgery |
CLINICAL/RESEARCH INTERESTS: Cancer Biology, Cell Biology, Cell Signaling, Computational Biology, Genetics, Genomics, Molecular Biology, Surgery, Systems Biology |
Chrystal Starbird, PhD |
| Clinical / Research Focus: My lab studies the structural basis of receptor tyrosine kinase activation, with an initial focus on TAM receptors. Specifically, we are interested in understanding the role membrane lipids play in TA … Read more |
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AFFILIATIONS: Biochemistry & Biophysics, Lineberger Cancer Center |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Biophysics, Cancer Biology, Cell Signaling, Drug Discovery, Immunology, Pharmacology, Structural Biology |
Brian D. Strahl, PhD |
| Clinical / Research Focus: Eukaryotic genomes are packaged into the nuclei of cells through the actions of histone proteins. These proteins not only play a role in condensing the genome but are fundamental to establishing and m … Read more |
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AFFILIATIONS: Biochemistry & Biophysics |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Bioinformatics, Biophysics, Cancer Biology, Cell Biology, Cell Signaling, Chemical Biology, Computational Biology, Epigenetics and Chromatin Biology, Genetics, Genomics, HIV/AIDS, Microbiology, Microscopy, Molecular Biology, Organismal Biology, Stem Cells, Structural Biology |
Joan M. Taylor, PhD |
| Clinical / Research Focus: The goal of our research is to identify signaling mechanisms that contribute to normal and pathophysiological cell growth in the cardiovascular system. We study cardiac and vascular development as we … Read more |
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AFFILIATIONS: McAllister Heart Institute, Pathology & Lab Medicine |
CLINICAL/RESEARCH INTERESTS: Cardiovascular Biology, Cell Signaling, Developmental Biology, Genetics, Pathology |
Roland Tisch, PhD |
| Clinical / Research Focus: Our work focuses on T cell-mediated autoimmunity with a particular interest in type 1 diabetes. Efforts involve defining the events driving the breakdown of self-tolerance within the T cell compartmen … Read more |
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AFFILIATIONS: Lineberger Cancer Center, Microbiology & Immunology |
CLINICAL/RESEARCH INTERESTS: Cell Signaling, Diabetes, Gene Therapy, Immunology, Molecular Medicine, Nanomedicine, Pathology, Translational Medicine |
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AFFILIATIONS: Center for Environmental Medicine, Asthma & Lung Biology (CEMALB), Toxicology |
CLINICAL/RESEARCH INTERESTS: Cardiovascular Biology, Cell Signaling, Physiology, Toxicology, Translational Medicine |
Cyrus Vaziri, PhD |
| Clinical / Research Focus: Our broad long-term goal is to understand how mammalian cells maintain ordered control of DNA replication during normal passage through an unperturbed cell cycle, and in response to genotoxins (DNA-da … Read more |
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AFFILIATIONS: Genetics, Pathology & Lab Medicine, Toxicology |
CLINICAL/RESEARCH INTERESTS: Cancer Biology, Cell Biology, Cell Signaling, Molecular Biology, Toxicology |
Barbara Vilen, PhD |
| Clinical / Research Focus: My laboratory studies systemic lupus erythematosus (SLE), a heterogeneous autoimmune disease associated with tissue damage in skin, kidneys, lung, heart, brain, and vasculature. Murine and human studi … Read more |
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AFFILIATIONS: Microbiology & Immunology |
CLINICAL/RESEARCH INTERESTS: Arthritis, Cell Biology, Cell Signaling, Immunology, Translational Medicine |
Yisong Wan, PhD |
| Clinical / Research Focus: We are a molecular genetic laboratory studying immune functions by combining mouse models, mulit-omics, molecular, biochemical and genetic approaches. The focus of our research is to investigate the m … Read more |
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AFFILIATIONS: Lineberger Cancer Center, Microbiology & Immunology |
CLINICAL/RESEARCH INTERESTS: Aging/Geriatrics, Cell Signaling, Gene Therapy, Genetics, Immunology |
Ellen R. Weiss, PhD |
| Clinical / Research Focus: My research involves understanding the regulation of visual signaling pathways in the vertebrate retina using mice and zebrafish as model organisms. In the past 20 years we have discovered what was a … Read more |
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AFFILIATIONS: Cell Biology & Physiology, Genetics, Neuroscience Center |
CLINICAL/RESEARCH INTERESTS: Biochemistry, Cell Biology, Cell Signaling, Metabolism, Neurobiology, Physiology, Systems Biology |







