Author Archives: samweiss

Alcohol drinking that persists despite negative consequences is a core feature of alcohol use disorder (AUD). Here we investigate whether individual variability in this behavior are due to extended alcohol exposure or pre-existing differences in rats.

In this manuscript we used a mouse model of dementia that harbors a human mutation in the tau protein. We found that neurons that are lost in Alzheimer’s Disease (locus coeruleus norepinephrine neurons) have reduced function as compared to their age matched controls.

We developed an explainable AI model that analyzes 3D CBCT scans to automatically classify and measure upper airway obstruction caused by adenoid hypertrophy in children. This tool provides clinicians with clear visual explanations and accurate assessments to support diagnosis and treatment planning.

Factors identified with a higher odds of leaving outpatient psychiatric care during COVID-19 included demographic (male sex, uninsured (self-pay) status), behavioral (inactive patient health portal), and diagnostic (anxiety and trauma stressor disorders, pervasive and specific developmental disorders, and disorders of childhood) factors. These results highlight that the reasons patients left...

Our women’s mood disorders group produced this case series on our experience treating patients with zuranolone for severe postpartum depression with suicidality.

Estrogen treatment during menopause increased right hippocampal volumes in women without depression.

We investigated how different breathing techniques impact electrical activity in the brain.

Research led by Dr. Robert Mealer describes how a unique class of sugar molecules in the brain is enriched a specialized structures called nodes of Ranvier. This work provides new insight to a group of genes that are involved with genetic disorders of the brain, including schizophrenia.

This paper describes the learning health system model used to create Connection Learning Healthcare System (CLHS): a network of academic institutions, state behavioral health systems, and early psychosis specialty care programs in Pennsylvania and Maryland. It reviews lessons learned and areas of ongoing attention.

Meet three brothers, all UNC psychiatrists and double Tar Heels.