James R Yankaskas, MD

Research Interests

Dr. James Yankaskas, Professor of Medicine

Airway diseases, Cystic Fibrosis, critical care medicine, lung lavage, bronchoscopy.

Biographical Sketch

Jim Yankaskas received a B.S. in Aeronautics and Astronautics from M.I.T., an M.S. in Operations Research from N.Y.U., and worked as an Analytic Design Engineer at Sikorsky Aircraft for 5 years. He then received his M.D. from the University of Connecticut, completed residency training in Internal Medicine at the University of North Carolina at Chapel Hill [UNC] and fellowships in pulmonary medicine at Duke University and UNC. He is Professor of Medicine at UNC, where he is Associate Chair of the Pulmonary Disease and Critical Care Medicine Division, and Medical Director of the Medical ICU and the Medical Progressive Care Unit.

In 1985 Dr. Yankaskas developed and reported the human airway epithelial cell cultures that preserve the ion transport properties that characterize cystic fibrosis [CF] and non-CF airways. In 1989 he developed immortalized CF and non-CF cell lines that replicate these features (link to paper, HBE1 culture recommendations and Media). He founded the UNC CF Center Tissue Procurement and Cell Culture Core facility in 1984. He has published extensively on pulmonary diseases, especially cystic fibrosis in adults. He co-directs the UNC Adult Cystic Fibrosis Program and co-chaired CF Foundation consensus committees on Lung Transplant for CF and on CF Adult Care. He served on the CF Foundation Center Committee for 11 years and was the first internist to chair that accreditation body [2005-2009]. His current efforts focus on integrating laboratory research with clinical problems, facilitating clinical research and drug development, and improving clinical care by developing and applying quality improvement methods.

Contact Information

4135 Bioinformatics Building
Campus Box #7020
The University of North Carolina at Chapel Hill
Chapel Hill, NC 27599-7248
Phone: (919) 966-2531
E-mail: pwsjry@med.unc.edu