Sarah Council is a graduate student in the laboratory of Dr. Matthew Wolfgang.

Research Focus

The goal of my research is to determine the role of the oral anaerobic bacterium, Prevotella melaninogenica, in Cystic Fibrosis (CF) disease pathogenesis by examining the organism’s ability to elicit a CF-specific immune response and an iron dependent virulence mechanism. My dissertation will utilize the resources of the Cystic Fibrosis Center at UNC to acquire relevant clinical samples and to foster a basic science-clinical collaboration. Current therapy in CF does not typically include antibiotics directed against anaerobes, as such, the outcome of the proposed experiments could ultimately impact clinical practice.

Contact Information

4029 Thurston-Bowles Bldg.
The University of North Carolina at Chapel Hill
Campus Box #7248
Chapel Hill, NC 27599-7248
Phone: (919) 966-5333
Email: councils@dentistry.unc.edu