|Juliana Sesma, PhD, Postdoctoral Research Associate|
Juliana Sesma, PhD, is Postdoctoral Research Associate in the laboratory of Dr. Eduardo Lazarowski.
Dr. Juliana Sesma is a molecular biologist who joined the Lazarowski’s lab in 2006. She played a key role in dissecting the mechanisms by which epithelial cells release UDP-sugars. Juliana’s work demonstrated that, by controlling the entry of UDP-sugars to the secretory pathway, Golgi resident UDP-sugar transporters regulate the exocytotic release of UDP-N-acetylglucosamine and other UDP-sugars via the constitutive pathway. Dr. Sesma continues working on mechanisms of nucleotide release from vesicles, and has also expanded her work to study the contribution of conductive pathways, e.g., hemichannels, in ATP release. A second area of research undertaken by Dr. Sesma is on the role of purinergic receptors in inflammatory cells, with a focus on the signal transduction properties of the UDP-sugar-sensing P2Y14 receptor.
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