As part of the Blood Research Center, we participate in two types of research studies. We do mouse model studies of bleeding and wound healing to support research questions about the role of hemostasis to promote healthy physiology. We also use our background in protein chemistry and enzyme kinetics to collaborate on studies looking at the molecular mechanisms that underlie both healthy hemostasis and the dysregulation of hemostasis seen in bleeding and thrombosis.
Our interest is in the cellular interactions, protein chemistry, and enzyme kinetics that are behind the molecular mechanisms of both healthy hemostasis and the dysregulation of hemostasis seen in bleeding and thrombosis. Part of our research focus is the mechanisms of novel coagulation molecules and novel antithrombotics. Another focus of our work is developing mathematical models of coagulation and thrombus formation that will provide a basis for new drug development.
Jen-Yea (Peter) Chang, PhD
Researcher - Monroe Lab
Office: (919) 966-3313