October 6, 2022
An abstract submitted by Steven Grover, PhD on work conducted in the laboratory of Nigel Mackman, PhD was selected for presentation in the plenary scientific session at the 64th American Society of Hematology annual meeting. While conducting this work Dr Grover was supported by the UNC Blood Research Center T32 Post-Doctoral Training Program in Benign …
September 19, 2022
In the NIH-funded ‘American Trial Using Tranexamic Acid in Thrombocytopenia (A-TREAT)’ trial, UNC was one of 3 participating clinical centers to enroll patients with platelet transfusion-dependence due to therapy for hematologic malignancies. Between 2016 and 2020, 337 patients were randomized in a double blind fashion to tranexamic acid (TXA) or placebo. Ultimately, no benefit of …
August 20, 2022
Matthew Flick, PhD was recently awarded a NIH U01 grant, which is part of the Pancreatic Ductal Adenocarcinoma (PDAC) Stromal Reprogramming Consortium (PSRC). This is an MPI award that Dr. Flick received with collaborators Bumsoo Han, PhD at Purdue University and Melissa Fishel, PhD at the Indiana University School of Medicine. The title of the …
July 28, 2022
Drs. Raj Kasthuri and Yara Park of the UNC BRC, along with multiple alumni of the UNC hematology and transfusion medicine fellowships, co-authored a multi-institutional investigation into the role of race in the response of TTP patients to rituximab that has been accepted for publication in Blood. The study included 645 TTP patients from …
July 26, 2022
The focus of the grant is to investigate red blood cell alloimmunization risk using the REDS-III databases. Red blood cell (RBC) alloimmunization is a leading cause of morbidity and mortality in transfusion and pregnancy settings, resulting in hemolytic reactions and other adverse sequelae such as hemolytic disease of the fetus and newborn. Alloimmunization occurs in …
July 22, 2022
Dr. Patrick Ellsworth has been awarded the Access to Insight 2022 Basic Research Grant, totaling 63,000 Euros! This was a competitive grant with international applicants. Dr. Ellsworth’s project is titled “Mechanistic Investigation of Factor IX/IXa Synergy with Emicizumab” and he will be working with Dr. Monroe here of the BRC and Dr. Maureane Hoffman at Duke …
July 22, 2022
Effective July 1, 2022, Dr. Alisa Wolberg began service as the new Chair of the Hemostasis, Thrombosis, Blood Cells, and Transfusion study section of the NHLBI. She will serve a 2-year term in this role. Congratulations, Dr. Wolberg!
June 16, 2022
“A gene therapy clinical trial for hemophilia shows promise and could be approved by the FDA later this year — a feat made possible, in part, by UNC-Chapel Hill’s 70-year-old research program.” Click here to read the article.
May 11, 2022
Research performed at the BRC will be well represented at the 30th Congress of the International Society on Thrombosis and Haemostasis meeting in London, UK from July 9-13. A list of scheduled oral presentations and posters is included at this link.
May 4, 2022
Erica Sparkenbaugh, PhD, has been awarded a NC TRaCS $2K Pilot Grant for her study “Evaluation of Pre-thrombotic Markers in Female Patients with Sickle Cell Disease on Hormonal Contraception”. Congrats, Erica!
April 30, 2022
Woosuk Steve Hur, a postdoctoral fellow in the Flick Lab, has been awarded a Canadian Institutes of Health Research (CIHR) Postdoctoral Fellowship. This award covers salary support and provides funds for travel for 2 years.
April 27, 2022
Katharine King, a third year undergraduate from the biology department working in Dr. Flick’s lab, gave an invited oral presentation at the Nutrition and Obesity Research Center (NORC) Symposium last week. Her presentation was entitled: “Elimination of fibrin(ogen)-aMb2-binding function, but not fibrinogen deficiency, protects against obesity and metabolic syndrome” Katie won the undergraduate student oral …