News Archives | UNC Blood Research Center

Matthew Vander Ploeg, a graduate student in BCBP and a member of the BRC in Dr. Bergmeier’s lab, published his first author manuscript in Blood Advances. The study describes the development of high-throughput platelet migration assay, facilitated by novel deep learning-based image analysis pipeline. Using this new platform, Matt was able to show that platelet …

Dr. Yohei Hisada delivered an invited talk during a plenary session at the International Conference on Thrombosis and Hemostasis Issues in Cancer (https://icthic.com/en). The title of the presentation was “Tissue Factor-Driven Coagulopathy and Bleeding in Acute Leukemia: Clinical and Preclinical Insights.”

David Paul, PhD (Assistant Professor) and David Rocco (graduate student, Cell Biology and Physiology) from the Bergmeier lab publish co-first author paper in Blood describing a new signaling pathway critical for platelet adhesion under arterial shear conditions. The findings of this study markedly improve our understanding of G protein signaling and integrin function in platelets, …

In a study collaboration with colleagues from the Universities of Cardiff and Aberdeen in the UK, Anton Ilich and Nigel Key authored a study demonstrating the ability of their novel in-house fibrinolytic activation screening test (‘FAST’) to detect the severe and potentially lethal form of PPH, known as acute obstetric coagulopathy. The paper was published …

Dr. Matthew Flick received an award from Glycos Biomedical Ltd. for his work entitled “GBM-1511 as Adjunctive Sepsis Therapeutic for Staphylococcus Aureus and Streptococcus Pneumonia”. Congratulations Dr. Flick!

Steve Hur, PhD was selected to receive a Career Development Award from the American Heart Association totaling $77,000 every year for the next three years. Congratulations Dr. Hur!

Dr. Erica Sparkenbaugh was awarded the UNC School of Medicine Office of Research Translational Team Science Award (TTSA) pilot grant for her application titled “Hypoxemia-Induced Platelet Activation in Sickle Cell Disease Pregnancy: Mechanisms and Therapeutic Targets”. The team includes Drs. Erica Sparkenbaugh and Mofiyin Obadina from the Department of Medicine. Congratulations Dr. Sparkenbaugh!

Bergmeier proposal receives NIH/NHLBI R35 Outstanding Investigator Award. The award is intended to “promote scientific productivity and innovation by providing long-term support and increased flexibility to experienced Principal Investigators … whose outstanding record of research demonstrate their ability to make major contributions to the heart, lung, blood and sleep (HLBS) research.” Lead PI: Wolfgang Bergmeier Proposal …

Abigail Ballard-Kordeliski, former graduate student and member of Bergmeier lab, published paper in Haematologica. Paper describes new mechanistic findings on role of small G proteins in platelet pro-coagulant response. https://pubmed.ncbi.nlm.nih.gov/41784022/

Robert H. Lee, PhD, Wolfgang Bergmeier, PhD, Matthew J. Flick, PhD and Steve Hur, PhD, published collaborative paper in Blood, 1st author is Robert Lee – senior author is Steve Hur (Pathology). Paper describes new findings on the role of fibrinogen aC-region in arterial thrombosis in hypofibrinogenemic conditions, establishing a link to platelets via the …

Kadri Kangro, Samer Issa, Alisa Wolberg and Matthew Flick authored “SARS-CoV-2 spike protein can bind fibrin(ogen), but does not alter plasma fibrin formation, clot structure, or lysis” Link to publication

Stephan Moll, MD, UNC BRC member, and Steven Grover, PhD, former BRC member, are coinvestigators on a 5-year NASA study called ‘Venous Flow’ that studies the risk of venous thromboembolism (VTE) in zero gravity [ref 1]. The past finding of a jugular deep vein thrombosis (DVT) in an astronaut on the International Space Station …

Category: News

Matthew Vander Ploeg published his first author manuscript in Blood Advances

Dr. Yohei Hisada spoke at the International Conference on Thrombosis and Hemostasis Issues in Cancer

David Paul, PhD and David Rocco from the Bergmeier Lab publish co-first author paper in Blood

Key Lab publishes study demonstrating the utility of a novel assay of fibrinolytic activation in post-partum hemorrhage

Matthew Flick, PhD, receives Award from Glycos Biomedical

Steve Hur, PhD, receives AHA Career Development Award

Erica Sparkenbaugh, PhD receives TTSA Award

Bergmeier proposal receives NIH/NHLBI R35 Outstanding Investigator Award

Abigail Ballard-Kordeliski, PhD, former graduate student, published paper in Haematologica

Robert H. Lee, Wolfgang Bergmeier, Matthew J. Flick, and Steve Hur wrote article featured in Blood online publication titled “The fibrinogen αC region promotes arterial thrombosis in the context of hypofibrinogenemia”

Kadri Kangro, PhD of the Flick Lab first authored in ATVB

Stephan Moll, MD, UNC BRC member, and Steven Grover, PhD, former BRC member, are coinvestigators on a 5-year NASA study called ‘Venous Flow’ that studies the risk of venous thromboembolism (VTE) in zero gravity [ref 1].