June 16, 2022
“A gene therapy clinical trial for hemophilia shows promise and could be approved by the FDA later this year — a feat made possible, in part, by UNC-Chapel Hill’s 70-year-old research program.” Click here to read the article.
May 11, 2022
Research performed at the BRC will be well represented at the 30th Congress of the International Society on Thrombosis and Haemostasis meeting in London, UK from July 9-13. A list of scheduled oral presentations and posters is included at this link.
May 4, 2022
Erica Sparkenbaugh, PhD, has been awarded a NC TRaCS $2K Pilot Grant for her study “Evaluation of Pre-thrombotic Markers in Female Patients with Sickle Cell Disease on Hormonal Contraception”. Congrats, Erica!
April 30, 2022
Woosuk Steve Hur, a postdoctoral fellow in the Flick Lab, has been awarded a Canadian Institutes of Health Research (CIHR) Postdoctoral Fellowship. This award covers salary support and provides funds for travel for 2 years.
April 27, 2022
Katharine King, a third year undergraduate from the biology department working in Dr. Flick’s lab, gave an invited oral presentation at the Nutrition and Obesity Research Center (NORC) Symposium last week. Her presentation was entitled: “Elimination of fibrin(ogen)-aMb2-binding function, but not fibrinogen deficiency, protects against obesity and metabolic syndrome” Katie won the undergraduate student oral …
April 5, 2022
On April 1st, 2022, Nigel Mackman, PhD presented the inaugural J. Evans Sadler Lectureship – ‘Mechanisms of Cancer-Associated Thrombosis’
April 4, 2022
Platelets are critical in hemostasis and a major contributor to arterial thrombosis (AT). (Pre)clinical studies suggest platelets also contribute to venous thrombosis (VT), but the mechanisms are largely unknown. Jean Marie Mwiza, a graduate student in the Pathology department jointly supervised by Drs. Alisa Wolberg and Wolfgang Bergmeier, recently spear-headed an international team of investigators …
April 4, 2022
Platelet homeostasis, i.e. a stable platelet count in the circulation, is dependent on a tight regulation of both platelet production and clearance. Dr. Robert Lee, in collaboration with members of the Bergmeier lab, the Flick lab, and international collaborators, recently published their studies on the effect of uninhibited signaling by the small GTPase Rap1 on …
March 17, 2022
Dr. Nigel Key co-authored a manuscript describing the pivotal multi-center Phase 3 clinical trial of adeno-associated virus 5 (AAV5)- based gene therapy for severe hemophilia A that was published in the New England Journal of Medicine on March 17, 2022. The trial sponsor was Biomarin Pharmaceutical. Of 134 participants with severe hemophilia who were enrolled, …
March 3, 2022
Stephan Moll, MD gave a presentation at the NFL Combine Scientific Meeting on March 2, 2022 on “Athletes and Venous Thromboembolism: Intermittent Anticoagulation Management Strategy – Update” Following his initial Feb 2020 in-person presentation to the NFL team’s Sports Medicine physicians at the annual NFL Physicians’ Society meeting at the NFL Combine in Indianapolis, Dr. …
March 2, 2022
Brandi Reeves, MD, Assistant Professor of Medicine and Rafal Pawlinski, PhD, Lenvil Lee Rothrock Distinguished Professor of Medicine, were awarded a $50,000 TraCS Translational Team Science pilot grant to study Hypoxia Inducible Factors in Myeloproliferative Neoplasm-Associated Thrombosis. NC TraCS Award Announcements
February 28, 2022
Nigel Key, MB, ChB, FRCP has been awarded a 5-year, $2.2 million T32 grant from the National Heart, Lung, and Blood Institute (NHLBI). Now closely aligned with the benign hematology research areas of focus in the Blood Research Center (hemostasis, thrombosis and sickle cell disease), the program will continue to recruit MD and PhD trainees for …