Research Interests: At the intersection of gene regulation and iron homeostasis are Poly (rC)-Binding Proteins (PCBPs). Thought to be the primary metallochaperone for iron in the cell, PCBPs are required for cell viability. However, the impact of iron-deficiency on global cellular gene regulation is lacking. Using biophysical, biochemical, and molecular biology techniques, gene regulation by PCBPs, in the context of cellular iron homeostasis, can be illustrated.
Matt Mehlenbacher, PhD
Postdoctoral Fellow, T32 Trainee
