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Wolberg Lab Department: Pathology and Laboratory Medicine

Key Lab Department of Medicine, Division of Hematology

Research performed at the BRC will be well represented at the 30th Congress of the International Society on Thrombosis and Haemostasis meeting in London, UK from July 9-13. A list of scheduled oral presentations and posters is included at this link.

Erica Sparkenbaugh, PhD, has been awarded a NC TRaCS $2K Pilot Grant for her study “Evaluation of Pre-thrombotic Markers in Female Patients with Sickle Cell Disease on Hormonal Contraception”. Congrats, Erica!

Woosuk Steve Hur, a postdoctoral fellow in the Flick Lab, has been awarded a Canadian Institutes of Health Research (CIHR) Postdoctoral Fellowship. This award covers salary support and provides funds for travel for 2 years.

Katharine King, a third year undergraduate from the biology department working in Dr. Flick’s lab, gave an invited oral presentation at the Nutrition and Obesity Research Center (NORC) Symposium last week. Her presentation was entitled: “Elimination of fibrin(ogen)-aMb2-binding function, but not fibrinogen deficiency, protects against obesity and metabolic syndrome” Katie...

On April 1st, 2022, Nigel Mackman, PhD presented the inaugural J. Evans Sadler Lectureship – ‘Mechanisms of Cancer-Associated Thrombosis’

Platelets are critical in hemostasis and a major contributor to arterial thrombosis (AT). (Pre)clinical studies suggest platelets also contribute to venous thrombosis (VT), but the mechanisms are largely unknown. Jean Marie Mwiza, a graduate student in the Pathology department jointly supervised by Drs. Alisa Wolberg and Wolfgang Bergmeier, recently spear-headed...

Platelet homeostasis, i.e. a stable platelet count in the circulation, is dependent on a tight regulation of both platelet production and clearance. Dr. Robert Lee, in collaboration with members of the Bergmeier lab, the Flick lab, and international collaborators, recently published their studies on the effect of uninhibited signaling by...

Dr. Nigel Key co-authored a manuscript describing the pivotal multi-center Phase 3 clinical trial of adeno-associated virus 5 (AAV5)- based gene therapy for severe hemophilia A that was published in the New England Journal of Medicine  on March 17, 2022. The trial sponsor was Biomarin Pharmaceutical. Of 134 participants with...

Stephan Moll, MD gave a presentation at the NFL Combine Scientific Meeting on March 2, 2022 on “Athletes and Venous Thromboembolism: Intermittent Anticoagulation Management Strategy – Update” Following his initial Feb 2020  in-person presentation to the  NFL team’s Sports Medicine physicians at the annual NFL Physicians’ Society meeting at the...

  Brandi Reeves, MD, Assistant Professor of Medicine and Rafal Pawlinski, PhD, Lenvil Lee Rothrock Distinguished Professor of Medicine, were awarded a $50,000 TraCS Translational Team Science pilot grant to study Hypoxia Inducible Factors in Myeloproliferative Neoplasm-Associated Thrombosis. NC TraCS Award Announcements