Department of Genetics Publications for January 10-23, 2021

Department of Genetics faculty, postdocs, students and collaborators published seven papers during Jan. 10-23, 2021.

 

 

Outcomes of Hormone-Receptor Positive, HER2-Negative Breast Cancers by Race and Tumor Biological Features. 

Benefield HC, Reeder-Hayes KE, Nichols HB, Calhoun BC, Love MI, Kirk EL, Geradts J, Hoadley KA, Cole SR, Earp HS, Olshan AF, Carey LA, Perou CM, Troester MA.

JNCI Cancer Spectr. 2020 Sep 23;5(1):pkaa072. doi: 10.1093/jncics/pkaa072. eCollection 2021 Feb.

PMID: 33442657

 

SCISSOR: a framework for identifying structural changes in RNA transcripts. 

Choi HY, Jo H, Zhao X, Hoadley KA, Newman S, Holt J, Hayward MC, Love MI, Marron JS, Hayes DN.

Nat Commun. 2021 Jan 12;12(1):286. doi: 10.1038/s41467-020-20593-3.

PMID: 33436599

 

IL-12 Family Cytokines in Cancer and Immunotherapy. 

Mirlekar B, Pylayeva-Gupta Y.

Cancers (Basel). 2021 Jan 6;13(2):E167. doi: 10.3390/cancers13020167.

PMID: 33418929

 

An Overview of Characteristics of Clinical Next-Generation Sequencing-Based Testing for Hematologic Malignancies. 

Zhang BM, Keegan A, Li P, Lindeman NI, Nagarajan R, Routbort MJ, Vasalos P, Kim AS, Merker JD.

Arch Pathol Lab Med. 2021 Jan 15. doi: 10.5858/arpa.2019-0661-CP. Online ahead of print.

PMID: 33450747

 

North Carolina’s multi-institutional pharmacogenomics efforts with the NC precision health collaborative. 

Patel JN, Voora D, Bell G, Bates J, Cipriani A, Bendz L, Frick A, Hamadeh I, McGee AS, Steuerwald N, Imhof S, Wiltshire T.

Pharmacogenomics. 2021 Jan 15. doi: 10.2217/pgs-2020-0156. Online ahead of print.

PMID: 33448876

 

HDAC inhibition results in widespread alteration of the histone acetylation landscape and BRD4 targeting to gene bodies. 

Slaughter MJ, Shanle EK, Khan A, Chua KF, Hong T, Boxer LD, Allis CD, Josefowicz SZ, Garcia BA, Rothbart SB, Strahl BD, Davis IJ.

Cell Rep. 2021 Jan 19;34(3):108638. doi: 10.1016/j.celrep.2020.108638.

PMID: 33472068

 

Compression of quantification uncertainty for scRNA-seq counts. 

Van Buren S, Sarkar H, Srivastava A, Rashid NU, Patro R, Love MI.

Bioinformatics. 2021 Jan 20:btab001. doi: 10.1093/bioinformatics/btab001. Online ahead of print.

PMID: 33471073