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UNC Genetics PublicationsDepartment of Genetics faculty, postdocs, students and collaborators published 7 papers during January 29th – February 11th, 2023.


Behavioral phenotypes revealed during reversal learning are linked with novel genetic loci in diversity outbred mice. 

Bagley JR, Bailey LS, Gagnon LH, He H, Philip VM, Reinholdt LG, Tarantino LM, Chesler EJ, Jentsch JD.

Addict Neurosci. 2022 Dec;4:100045. doi: 10.1016/j.addicn.2022.100045. Epub 2022 Nov 4.

PMID: 36714272 Free PMC article.


Sex differences in interindividual gene expression variability across human tissues. 

Khodursky S, Jiang CS, Zheng EB, Vaughan R, Schrider DR, Zhao L.

PNAS Nexus. 2022 Oct 26;1(5):pgac243. doi: 10.1093/pnasnexus/pgac243. eCollection 2022 Nov.

PMID: 36712323 Free PMC article.


TIVAN-indel: A computational framework for annotating and predicting noncoding regulatory small insertions and deletions. 

Agarwal A, Zhao F, Jiang Y, Chen L.

Bioinformatics. 2023 Jan 27:btad060. doi: 10.1093/bioinformatics/btad060. Online ahead of print.

PMID: 36707993


Four-Year Laboratory Performance of the First College of American Pathologists In Silico Next-Generation Sequencing Bioinformatics Proficiency Testing Surveys. 

Furtado LV, Souers RJ, Vasalos P, Halley JG, Aisner DL, Nagarajan R, Voelkerding KV, Merker JD, Konnick EQ.

Arch Pathol Lab Med. 2023 Feb 1;147(2):137-142. doi: 10.5858/arpa.2021-0384-CP.

PMID: 35671151


Prdm6 drives ductus arteriosus closure by promoting ductus arteriosus smooth muscle cell identity and contractility. 

Zou M, Mangum KD, Magin JC, Cao HH, Yarboro MT, Shelton EL, Taylor JM, Reese J, Furey TS, Mack CP.

JCI Insight. 2023 Feb 7:e163454. doi: 10.1172/jci.insight.163454. Online ahead of print.

PMID: 36749647


Assay-related differences in SuPAR levels: implications for measurement and data interpretation. 

Vasbinder A, Raffield LM, Gao Y, Engstrom G, Quyyumi AA, Reiner AP, Reiser J, Hayek SS.

J Nephrol. 2023 Jan;36(1):157-159. doi: 10.1007/s40620-022-01344-7. Epub 2022 May 14.

PMID: 35567697 Free PMC article. No abstract available.


Dissecting and targeting noncanonical functions of EZH2 in multiple myeloma via an EZH2 degrader. 

Yu X, Wang J, Gong W, Ma A, Shen Y, Zhang C, Liu X, Cai L, Liu J, Wang GG, Jin J.

Oncogene. 2023 Feb 7. doi: 10.1038/s41388-023-02618-5. Online ahead of print.

PMID: 36747009