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UNC Genetics PublicationsDepartment of Genetics faculty, postdocs, students and collaborators published 10 papers during July 2nd – 15th, 2023.


An EZH2-NF-κB regulatory axis drives expression of pro-oncogenic gene signatures in triple negative breast cancer. 

Dardis GJ, Wang J, Simon JM, Wang GG, Baldwin AS.

iScience. 2023 Jun 14;26(7):107115. doi: 10.1016/j.isci.2023.107115. eCollection 2023 Jul 21.

PMID: 37416481 Free PMC article.


Host genetic background is a barrier to broadly effective vaccine-mediated protection against tuberculosis. 

Lai R, Gong DN, Williams T, Ogunsola AF, Cavallo K, Lindestam Arlehamn CS, Acolatse S, Beamer GL, Ferris MT, Sassetti CM, Lauffenburger DA, Behar SM.

J Clin Invest. 2023 Jul 3;133(13):e167762. doi: 10.1172/JCI167762.

PMID: 37200108 Free PMC article.


Evaluating power to detect recurrent selective sweeps under increasingly realistic evolutionary null models. 

Soni V, Johri P, Jensen JD.

Evolution. 2023 Jul 3:qpad120. doi: 10.1093/evolut/qpad120. Online ahead of print.

PMID: 37395482


Addressing multi-site functional MRI heterogeneity through dual-expert collaborative learning for brain disease identification. 

Fang Y, Potter GG, Wu D, Zhu H, Liu M.

Hum Brain Mapp. 2023 Aug 1;44(11):4256-4271. doi: 10.1002/hbm.26343. Epub 2023 May 25.

PMID: 37227019 Free PMC article.


SEESAW: detecting isoform-level allelic imbalance accounting for inferential uncertainty. 

Wu EY, Singh NP, Choi K, Zakeri M, Vincent M, Churchill GA, Ackert-Bicknell CL, Patro R, Love MI.

Genome Biol. 2023 Jul 12;24(1):165. doi: 10.1186/s13059-023-03003-x.

PMID: 37438847


Defining iNKT Cell Subsets and Their Function by Flow Cytometry. 

Gioulbasani M, Tsagaratou A.

Curr Protoc. 2023 Jul;3(7):e838. doi: 10.1002/cpz1.838.

PMID: 37428873


Protective effects of inhaled antioxidants against air pollution-induced pathological responses. 

Schichlein KD, Smith GJ, Jaspers I.

Respir Res. 2023 Jul 13;24(1):187. doi: 10.1186/s12931-023-02490-7.

PMID: 37443038 Review.


Chronic early life stress alters the neuroimmune profile and functioning of the developing zebrafish gut. 

Graves CL, Norloff E, Thompson D, Kosyk O, Sang Y, Chen A, Zannas AS, Wallet SM.

Brain Behav Immun Health. 2023 Jun 17;31:100655. doi: 10.1016/j.bbih.2023.100655. eCollection 2023 Aug.

PMID: 37449287 Free PMC article.


A Shared Pathogenic Mechanism for Valproic Acid and SHROOM3 Knockout in a Brain Organoid Model of Neural Tube Defects. 

Takla TN, Luo J, Sudyk R, Huang J, Walker JC, Vora NL, Sexton JZ, Parent JM, Tidball AM.

Cells. 2023 Jun 23;12(13):1697. doi: 10.3390/cells12131697.

PMID: 37443734


Rapid Whole-Genomic Sequencing and a Targeted Neonatal Gene Panel in Infants With a Suspected Genetic Disorder. 

Maron JL, Kingsmore S, Gelb BD, Vockley J, Wigby K, Bragg J, Stroustrup A, Poindexter B, Suhrie K, Kim JH, Diacovo T, Powell CM, Trembath A, Guidugli L, Ellsworth KA, Reed D, Kurfiss A, Breeze JL, Trinquart L, Davis JM.

JAMA. 2023 Jul 11;330(2):161-169. doi: 10.1001/jama.2023.9350.

PMID: 37432431