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UNC Genetics PublicationsDepartment of Genetics faculty, postdocs, students and collaborators published 9 papers during March 31st – April 13th, 2024.

Methylation patterns associated with C-reactive protein in racially and ethnically diverse populations. 

Lundin JI, Peters U, Hu Y, Ammous F, Avery CL, Benjamin EJ, Bis JC, Brody JA, Carlson C, Cushman M, Gignoux C, Guo X, Haessler J, Haiman C, Joehanes R, Kasela S, Kenny E, Lapalainien T, Levy D, Liu C, Liu Y, Loos RJF, Lu A, Matise T, North KE, Park SL, Ratliff SM, Reiner A, Rich SS, Rotter JI, Smith JA, Sotoodehnia N, Tracy R, Van den Berg D, Xu H, Ye T, Zhao W, Raffield LM, Kooperberg C; PAGE Study.

Epigenetics. 2024 Dec;19(1):2333668. doi: 10.1080/15592294.2024.2333668. Epub 2024 Apr 3.

PMID: 38571307


Demographic history and the efficacy of selection in the globally invasive mosquito Aedes aegypti

Kent TV, Schrider DR, Matute DR.

bioRxiv [Preprint]. 2024 Mar 12:2024.03.07.584008. doi: 10.1101/2024.03.07.584008.

PMID: 38559089 Free PMC article. Preprint.


DELVE: feature selection for preserving biological trajectories in single-cell data. 

Ranek JS, Stallaert W, Milner JJ, Redick M, Wolff SC, Beltran AS, Stanley N, Purvis JE.

Nat Commun. 2024 Mar 29;15(1):2765. doi: 10.1038/s41467-024-46773-z.

PMID: 38553455 Free PMC article.


Air Pollution Exposure and Interstitial Lung Features in SPIROMICS Participants with COPD. 

Baddour NA, Paulin LM, Gassett AJ, Woo H, Hoffman EA, Newell JD Jr, Woodruff PG, Pirozzi CS, Barjaktarevic I, Barr RG, O’Neal W, Han MK, Martinez FJ, Peters SP, Hastie AT, Hansel NN, Ortega VE, Kaufman JD, Sack CS.

Ann Am Thorac Soc. 2024 Apr 3. doi: 10.1513/AnnalsATS.202308-741OC. Online ahead of print.

PMID: 38568439


FPLS-DC: Functional partial least squares through distance covariance for imaging genetics. 

Pan W, Shan Y, Li C, Huang S, Li T, Li Y, Zhu H.

Bioinformatics. 2024 Mar 29:btae173. doi: 10.1093/bioinformatics/btae173. Online ahead of print.

PMID: 38552322


Genetically encoded transcriptional plasticity underlies stress adaptation in Mycobacterium tuberculosis. 

Bei C, Zhu J, Culviner PH, Gan M, Rubin EJ, Fortune SM, Gao Q, Liu Q.

Nat Commun. 2024 Apr 10;15(1):3088. doi: 10.1038/s41467-024-47410-5.

PMID: 38600064 Free PMC article.


Meta-analysis of epigenetic aging in schizophrenia reveals multifaceted relationships with age, sex, illness duration, and polygenic risk. 

Ori APS, Olde Loohuis LM, Guintivano J, Hannon E, Dempster E, St Clair D, Bass NJ, McQuillin A, Mill J, Sullivan PF, Kahn RS, Horvath S, Ophoff RA.

Clin Epigenetics. 2024 Apr 8;16(1):53. doi: 10.1186/s13148-024-01660-8.

PMID: 38589929 Free PMC article.


SARS-CoV-2 variant of concern fitness and adaptation in primary human airway epithelia. 

Meganck RM, Edwards CE, Mallory ML, Lee RE, Dang H, Bailey AB, Wykoff JA, Gallant SC, Zhu DR, Yount BL, Kato T, Shaffer KM, Nakano S, Cawley AM, Sontake V, Wang JR, Hagan RS, Miller MB, Tata PR, Randell SH, Tse LV, Ehre C, Okuda K, Boucher RC, Baric RS.

Cell Rep. 2024 Apr 10;43(4):114076. doi: 10.1016/j.celrep.2024.114076. Online ahead of print.

PMID: 38607917


Genetic Ancestry-specific Molecular and Survival Differences in Admixed Patients With Breast Cancer. 

Telonis AG, Rodriguez DA, Spanheimer PM, Figueroa ME, Goel N.

Ann Surg. 2024 May 1;279(5):866-873. doi: 10.1097/SLA.0000000000006135. Epub 2023 Dec 11.

PMID: 38073557