Department of Genetics faculty, postdocs, students and collaborators published nine papers during June 14-27, 2020.

 

The KMT2D Kabuki syndrome histone methylase controls neural crest cell differentiation and facial morphology.
Shpargel KB, Mangini CL, Xie G, Ge K, Magnuson T.
Development. 2020 Jun 15. pii: dev.187997. doi: 10.1242/dev.187997. [Epub ahead of print]
PMID: 32541010

 

A pan-cancer analysis of the frequency of DNA alterations across cell cycle activity levels.
Lundberg A, Lindström LS, Parker JS, Löverli E, Perou CM, Bergh J, Tobin NP.
Oncogene. 2020 Jun 24. doi: 10.1038/s41388-020-1367-4. [Epub ahead of print]
PMID: 32581248

 

Landscape and Selection of Vaccine Epitopes in SARS-CoV-2.
Smith CC, Entwistle S, Willis C, Vensko S, Beck W, Garness J, Sambade M, Routh E, Olsen K, Kodysh J, O’Donnell T, Haber C, Heiss K, Stadler V, Garrison E, Grant OC, Woods RJ, Heise M, Vincent BG, Rubinsteyn A.
bioRxiv. 2020 Jun 4. pii: 2020.06.04.135004. doi: 10.1101/2020.06.04.135004.
PMID: 32577654

 

A community-maintained standard library of population genetic models.
Adrion JR, Cole CB, Dukler N, Galloway JG, Gladstein AL, Gower G, Kyriazis CC, Ragsdale AP, Tsambos G, Baumdicker F, Carlson J, Cartwright RA, Durvasula A, Gronau I, Kim BY, McKenzie P, Messer PW, Noskova E, Ortega Del Vecchyo D, Racimo F, Struck TJ, Gravel S, Gutenkunst RN, Lohmueller KE, Ralph PL, Schrider DR, Siepel A, Kelleher J, Kern AD.
Elife. 2020 Jun 23;9. pii: e54967. doi: 10.7554/eLife.54967. [Epub ahead of print]
PMID: 32573438

 

Eukaryotic phosphatase inhibitors enhance colistin efficacy in gram-negative bacteria.
Barker WT, Jania LA, Melander RJ, Koller BH, Melander C.
Chem Biol Drug Des. 2020 Jun 19. doi: 10.1111/cbdd.13735. [Epub ahead of print]
PMID: 32562384

 

Transcriptome-wide Regulation of Key Developmental Pathways in the Mouse Neural Tube by Prenatal Alcohol Exposure.
Boschen KE, Ptacek TS, Simon JM, Parnell SE.
Alcohol Clin Exp Res. 2020 Jun 18. doi: 10.1111/acer.14389. [Epub ahead of print]
PMID: 32557641

 

Training the next generation of genomic medicine providers: trends in medical education and national assessment.
Dasgupta S, Feldman GL, Powell CM, Toriello HV, Westman J, Wilson WG, Waggoner DJ.
Genet Med. 2020 Jun 18. doi: 10.1038/s41436-020-0855-9. [Epub ahead of print]
PMID: 32555416

 

CDK-Regulated Phase Separation Seeded by Histone Genes Ensures Precise Growth and Function of Histone Locus Bodies.
Hur W, Kemp JP Jr, Tarzia M, Deneke VE, Marzluff WF, Duronio RJ, Di Talia S.
Dev Cell. 2020 Jun 19. pii: S1534-5807(20)30453-6. doi: 10.1016/j.devcel.2020.06.003. [Epub ahead of print]
PMID: 32579968

 

Decreased Colonic Activin Receptor-Like Kinase 1 Disrupts Epithelial Barrier Integrity in Patients with Crohn’s disease.
Toyonaga T, Steinbach EC, Keith BP, Barrow JB, Schaner MR, Wolber EA, Beasley C, Huling J, Wang Y, Allbritton NL, Chaumont N, Sadiq TS, Koruda MJ, Jain A, Long MD, Barnes EL, Herfarth HH, Isaacs KL, Hansen JJ, Shanahan MT, Rahbar R, Furey TS, Sethupathy P, Sheikh SZ.
Cell Mol Gastroenterol Hepatol. 2020 Jun 16. pii: S2352-345X(20)30094-1. doi: 10.1016/j.jcmgh.2020.06.005. [Epub ahead of print]
PMID: 32561494