Department of Genetics Publications January 2nd – 15th 2022

Department of Genetics faculty, postdocs, students and collaborators published 11 papers during January 2^nd – 15^th, 2022.

 

Collaboration between clinical and academic laboratories for sequencing SARS-CoV-2 genomes. 

Wang J, Hawken SE, Jones CD, Hagan RS, Bushman F, Everett J, Miller MB, Rodino KG.

J Clin Microbiol. 2022 Jan 5:JCM0128821. doi: 10.1128/JCM.01288-21. Online ahead of print.

PMID: 34985985

 

Development and Validation of Machine Learning-Based Race-Specific Models to Predict 10-Year Risk of Heart Failure: A Multicohort Analysis. 

Segar MW, Jaeger BC, Patel KV, Nambi V, Ndumele CE, Correa A, Butler J, Chandra A, Ayers C, Rao S, Lewis AA, Raffield LM, Rodriguez CJ, Michos ED, Ballantyne CM, Hall ME, Mentz RJ, de Lemos JA, Pandey A.

Circulation. 2021 Jun 15;143(24):2370-2383. doi: 10.1161/CIRCULATIONAHA.120.053134. Epub 2021 Apr 13.

PMID: 33845593

 

Mucopolysaccharidosis Type I Diagnosed by Aortic and Mitral Valve Replacement. 

Sherwood DJ, Adams MC, Mazzella AJ, Abid A, Prasada S, Muenzer J, Johnson SM, Yeung M.

JACC Case Rep. 2021 Dec 15;3(18):1891-1894. doi: 10.1016/j.jaccas.2021.10.013. eCollection 2021 Dec 15.

PMID: 34984346 Free PMC article.

 

Evaluation of the performance of a prior tacrolimus population pharmacokinetic kidney transplant model among adult allogeneic hematopoietic stem cell transplant patients. 

Zhu J, Campagne O, Torrice CD, Flynn G, Miller JA, Patel T, Suzuki O, Ptachcinski JR, Armistead PM, Wiltshire T, Mager DE, Weiner DL, Crona DJ.

Clin Transl Sci. 2021 May;14(3):908-918. doi: 10.1111/cts.12956. Epub 2021 Jan 27.

PMID: 33502111 Free PMC article. Clinical Trial.

 

Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia. 

Pardiñas AF, Smart SE, Willcocks IR, Holmans PA, Dennison CA, Lynham AJ, Legge SE, Baune BT, Bigdeli TB, Cairns MJ, Corvin A, Fanous AH, Frank J, Kelly B, McQuillin A, Melle I, Mortensen PB, Mowry BJ, Pato CN, Periyasamy S, Rietschel M, Rujescu D, Simonsen C, St Clair D, Tooney P, Wu JQ, Andreassen OA, Kowalec K, Sullivan PF, Murray RM, Owen MJ, MacCabe JH, O’Donovan MC, Walters JTR; Genetics Workstream of the Schizophrenia Treatment Resistance and Therapeutic Advances (STRATA) Consortium and the Schizophrenia Working Group of the Psychiatric Genomics Consortium (PGC), Ajnakina O, Alameda L, Barnes TRE, Berardi D, Bonora E, Camporesi S, Cleusix M, Conus P, Crespo-Facorro B, D’Andrea G, Demjaha A, Do KQ, Doody GA, Eap CB, Ferchiou A, Di Forti M, Guidi L, Homman L, Jenni R, Joyce EM, Kassoumeri L, Khadimallah I, Lastrina O, Muratori R, Noyan H, O’Neill FA, Pignon B, Restellini R, Richard JR, Schürhoff F, Španiel F, Szöke A, Tarricone I, Tortelli A, Üçok A, Vázquez-Bourgon J.

JAMA Psychiatry. 2022 Jan 12. doi: 10.1001/jamapsychiatry.2021.3799. Online ahead of print.

PMID: 35019943

 

INO80 requires a polycomb subunit to regulate the establishment of poised chromatin in murine spermatocytes. 

Chakraborty P, Magnuson T.

Development. 2022 Jan 1;149(1):dev200089. doi: 10.1242/dev.200089. Epub 2022 Jan 10.

PMID: 35006254

 

Genetic heterogeneity and subtypes of major depression. 

Nguyen TD, Harder A, Xiong Y, Kowalec K, Hägg S, Cai N, Kuja-Halkola R, Dalman C, Sullivan PF, Lu Y.

Mol Psychiatry. 2022 Jan 8. doi: 10.1038/s41380-021-01413-6. Online ahead of print.

PMID: 34997191

 

Validation of a combined ultrasound and bioluminescence imaging system with magnetic resonance imaging in orthotopic pancreatic murine tumors. 

Rojas JD, Joiner JB, Velasco B, Bautista KJB, Aji AM, Moore CJ, Beaumont NJ, Pylayeva-Gupta Y, Dayton PA, Gessner RC, Czernuszewicz TJ.

Sci Rep. 2022 Jan 7;12(1):102. doi: 10.1038/s41598-021-03684-z.

PMID: 34996939 Free PMC article.

 

PBRM1 inactivation promotes upregulation of human endogenous retroviruses in a HIF-dependent manner. 

Zhou M, Leung JY, Gessner KH, Hepperla AJ, Simon JM, Davis IJ, Kim WY.

Cancer Immunol Res. 2022 Jan 10:canimm.0480.2021. doi: 10.1158/2326-6066.CIR-21-0480. Online ahead of print.

PMID: 35013001

 

Targeting disialoganglioside GD2 with chimeric antigen receptor-redirected T cells in lung cancer. 

Reppel L, Tsahouridis O, Akulian J, Davis IJ, Lee H, Fucà G, Weiss J, Dotti G, Pecot CV, Savoldo B.

J Immunother Cancer. 2022 Jan;10(1):e003897. doi: 10.1136/jitc-2021-003897.

PMID: 35022195

 

Breast cancer treatment patterns by age and time since last pregnancy in the Carolina Breast Cancer Study Phase III. 

Vohra SN, Reeder-Hayes KE, Nichols HB, Emerson MA, Love MI, Olshan AF, Troester MA.

Breast Cancer Res Treat. 2022 Jan 10. doi: 10.1007/s10549-022-06511-9. Online ahead of print.

PMID: 35006482