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Kathleen Caron, PhD

Professor and Chair, Cell Biology & Physiology Professor, Genetics

Research Interests

Keywords: G protein-coupled receptors in cardiovascular development and physiology

Lab Website

Studies in the Caron Lab are focused on elucidating unique G protein-coupled receptor pathways that are important for the development and function of the cardiovascular system. Using a variety of gene-targeted animal models in conjunction with state-of-the-art in vitro cell biological systems, we have discovered fundamental roles for several secretin- and chemokine-family receptors in cardiovascular development and disease. Much of our recent work has focused on the pivotal roles that RAMPs (receptor activity-modifying proteins) play in controlling receptor function, cellular signaling, and physiology. The importance of the RAMP-receptor interaction is best exemplified by our work centered on the small blood protein, adrenomedullin – a potent lymphangiogenic vasodilator that serves as a strong prognostic indicator for many disease conditions.

Mentor Training:

  • Bias 101
  • Racial Equity Institute Training
  • Safe Zone Training
  • 2019 OGE Best Mentor Award

Training Program Affiliations:

  • Cell Biology and Physiology
  • Genetics and Molecular Biology

Publications

Kathleen Caron in UNC Genetics News

Kathleen Caron