Research Interests
Keywords: G protein-coupled receptors in cardiovascular development and physiology
Studies in the Caron Lab are focused on elucidating unique G protein-coupled receptor pathways that are important for the development and function of the cardiovascular system. Using a variety of gene-targeted animal models in conjunction with state-of-the-art in vitro cell biological systems, we have discovered fundamental roles for several secretin- and chemokine-family receptors in cardiovascular development and disease. Much of our recent work has focused on the pivotal roles that RAMPs (receptor activity-modifying proteins) play in controlling receptor function, cellular signaling, and physiology. The importance of the RAMP-receptor interaction is best exemplified by our work centered on the small blood protein, adrenomedullin – a potent lymphangiogenic vasodilator that serves as a strong prognostic indicator for many disease conditions.
Mentor Training:
- Bias 101
- Racial Equity Institute Training
- Safe Zone Training
- 2019 OGE Best Mentor Award
Training Program Affiliations:
- Cell Biology and Physiology
- Genetics and Molecular Biology
Publications
Kathleen Caron in UNC Genetics News
January 22, 2024
Department of Genetics Publications for January 7th – 20th 2024
Department of Genetics faculty, postdocs, students and collaborators published 12 papers during January 7th - 20th 2024.
December 11, 2023
UNC BCB and GMB Graduate Students Baran, Flores, McAfee, and Szymanski Volunteer as UNC Ambassadors in the Shadow a Scientist program
On November 29, UNC graduate students Kerstin Baran, JP Flores, Jessica McAfee, and Rachel Szymanski, volunteered their time and expertise for a Shadow a Scientist outreach event held on the UNC Chapel Hill campus.
May 7, 2023
Department of Genetics Publications for April 23rd – May 6th, 2023
Department of Genetics faculty, postdocs, students and collaborators published 11 papers during April 23rd – May 6th, 2023.
April 23, 2023
Department of Genetics Publications for April 9th – 22nd, 2023
Department of Genetics faculty, postdocs, students and collaborators published 15 papers during April 9th – 22nd, 2023.
January 2, 2023
Department of Genetics Publications for December 18th – 31st, 2022
Department of Genetics faculty, postdocs, students and collaborators published 10 papers during December 18th – 31st, 2022.
November 20, 2022
Department of Genetics Publications for November 6th – 19th, 2022
Department of Genetics faculty, postdocs, students and collaborators published 11 papers during November 6th – 19th, 2022.
August 16, 2022
Department of Genetics Publications for July 31st – August 13th, 2022
Department of Genetics faculty, postdocs, students and collaborators published 7 papers during July 31st – August 13th, 2022. A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids. Ramdas S, Judd J, Graham SE, Kanoni S, Wang Y, Surakka I, Wenz B, Clarke SL, Chesi A, Wells A, Bhatti KF, Vedantam S, …
June 6, 2022
Department of Genetics Publications May 22nd – June 4th, 2022
Department of Genetics faculty, postdocs, students and collaborators published 10 papers during May 22nd – June 4th, 2022.
May 9, 2022
Department of Genetics Publications April 24th – May 7th, 2022
Department of Genetics faculty, postdocs, students and collaborators published 14 papers during April 24th – May 7th, 2022.
February 14, 2022
Department of Genetics Publications: January 30th – February 12th, 2022
Department of Genetics faculty, postdocs, students and collaborators published 15 papers during January 30th – February 12th, 2022.
