Department of Genetics Publications for November 6th – 19th, 2022

Department of Genetics faculty, postdocs, students and collaborators published 11 papers during November 6^th – 19^th, 2022.

 

Intestinal epithelial cell barrier dysfunction and elevated Angiopoietin-like 4 identified in orally susceptible peanut allergy model. 

Steinbach EC, Smeekens JM, Roy S, Toyonaga T, Cornaby C, Perini LB, Berglind AE, Kulis MD, Kim EH, Ferris MT, Furey TS, Burks AW, Sheikh SZ.

Clin Exp Allergy. 2022 Nov 6. doi: 10.1111/cea.14248. Online ahead of print.

PMID: 36336910 No abstract available.

 

Collaborative study from the Bladder Cancer Advocacy Network for the genomic analysis of metastatic urothelial cancer. 

Damrauer JS, Beckabir W, Klomp J, Zhou M, Plimack ER, Galsky MD, Grivas P, Hahn NM, O’Donnell PH, Iyer G, Quinn DI, Vincent BG, Quale DZ, Wobker SE, Hoadley KA, Kim WY, Milowsky MI.

Nat Commun. 2022 Nov 4;13(1):6658. doi: 10.1038/s41467-022-33980-9.

PMID: 36333289 Free PMC article.

 

Editorial: DNA-based population screening for precision public health. 

Milko LV, Khoury MJ.

Front Genet. 2022 Oct 24;13:1061329. doi: 10.3389/fgene.2022.1061329. eCollection 2022.

PMID: 36353109 Free PMC article. No abstract available.

 

Endocardium-to-coronary artery differentiation during heart development and regeneration involves sequential roles of Bmp2 and Cxcl12/Cxcr4. 

D’Amato G, Phansalkar R, Naftaly JA, Fan X, Amir ZA, Rios Coronado PE, Cowley DO, Quinn KE, Sharma B, Caron KM, Vigilante A, Red-Horse K.

Dev Cell. 2022 Nov 2:S1534-5807(22)00759-6. doi: 10.1016/j.devcel.2022.10.007. Online ahead of print.

PMID: 36347256

 

Focused ultrasound-mediated blood-brain barrier opening in Alzheimer’s disease: long-term safety, imaging, and cognitive outcomes. 

Rezai AR, Ranjan M, Haut MW, Carpenter J, D’Haese PF, Mehta RI, Najib U, Wang P, Claassen DO, Chazen JL, Krishna V, Deib G, Zibly Z, Hodder SL, Wilhelmsen KC, Finomore V, Konrad PE, Kaplitt M; Alzheimer’s Disease Neuroimaging Initiative.

J Neurosurg. 2022 Nov 4:1-9. doi: 10.3171/2022.9.JNS221565. Online ahead of print.

PMID: 36334289

 

Reproducible changes in the anorexia nervosa gut microbiota following inpatient therapy remain distinct from non-eating disorder controls. 

Fouladi F, Bulik-Sullivan EC, Glenny EM, Thornton LM, Reed KK, Thomas S, Kleiman S, Watters A, Oakes J, Huh EY, Tang Q, Liu J, Djukic Z, Harper L, Trillo-Ordoñez Y, Sun S, Blakely I, Mehler PS, Fodor AA, Tarantino LM, Bulik CM, Carroll IM.

Gut Microbes. 2022 Jan-Dec;14(1):2143217. doi: 10.1080/19490976.2022.2143217.

PMID: 36398862

 

Protocol to isolate mature thymic T cell subsets using fluorescence-activated cell sorting for assessing gene expression by RNA-seq and transcription factor binding across the genome by CUT&RUN. 

Theofilatos D, Äijö T, Tsagaratou A.

STAR Protoc. 2022 Nov 11;3(4):101839. doi: 10.1016/j.xpro.2022.101839. eCollection 2022 Dec 16.

PMID: 36386867 Free PMC article.

 

Rare tandem repeat expansions associate with genes involved in synaptic and neuronal signaling functions in schizophrenia. 

Wen J, Trost B, Engchuan W, Halvorsen M, Pallotto LM, Mitina A, Ancalade N, Farrell M, Backstrom I, Guo K, Pellecchia G, Thiruvahindrapuram B, Giusti-Rodriguez P, Rosen JD, Li Y, Won H, Magnusson PKE, Gyllensten U, Bassett AS, Hultman CM, Sullivan PF, Yuen RKC, Szatkiewicz JP.

Mol Psychiatry. 2022 Nov 16. doi: 10.1038/s41380-022-01857-4. Online ahead of print.

PMID: 36380236

 

HER2DX genomic test in HER2-positive/hormone receptor-positive breast cancer treated with neoadjuvant trastuzumab and pertuzumab: A correlative analysis from the PerELISA trial. 

Guarneri V, Bras-Maristany F, Dieci MV, Griguolo G, Par L, Mar Ín-Aguilera M, Miglietta F, Bottosso M, Giorgi CA, Blasco P, Castillo O, Galv N P, Vivancos A, Villagrasa P, Parker JS, Perou CM, Conte P, Prat A.

EBioMedicine. 2022 Nov;85:104320. doi: 10.1016/j.ebiom.2022.104320. Epub 2022 Oct 29.

PMID: 36374768 Free PMC article. Clinical Trial.

 

Long-range chromosomal interactions increase and mark repressed gene expression during adipogenesis. 

Garske KM, Comenho C, Pan DZ, Alvarez M, Mohlke K, Laakso M, Pietiläinen KH, Pajukanta P.

Epigenetics. 2022 Dec;17(13):1849-1862. doi: 10.1080/15592294.2022.2088145. Epub 2022 Jun 23.

PMID: 35746833 Free PMC article.

 

Robust Genetic Model-Based SNP-set Association Test Using CauchyGM. 

Kim Y, Chi YY, Shen J, Zou F.

Bioinformatics. 2022 Nov 16:btac728. doi: 10.1093/bioinformatics/btac728. Online ahead of print.

PMID: 36383169