Department of Genetics Publications April 24th – May 7th, 2022

Department of Genetics faculty, postdocs, students and collaborators published 14 papers during April 24^th – May 7^th, 2022.

 

Ictal neural oscillatory alterations precede sudden unexpected death in epilepsy. 

Gu B, Levine NG, Xu W, Lynch RM, Pardo-Manuel de Villena F, Philpot BD.

Brain Commun. 2022 Mar 25;4(2):fcac073. doi: 10.1093/braincomms/fcac073. eCollection 2022.

PMID: 35474855 Free PMC article.

 

Transcriptome-wide analyses of adipose tissue in outbred rats reveal genetic regulatory mechanisms relevant for human obesity. 

Crouse WL, Das SK, Le T, Keele G, Holl K, Seshie O, Craddock A, Sharma NK, Comeau ME, Langefeld C, Hawkins GA, Mott R, Valdar W, Solberg Woods LC.

Physiol Genomics. 2022 Apr 25. doi: 10.1152/physiolgenomics.00172.2021. Online ahead of print.

PMID: 35467982

 

Molecular analysis of TCGA breast cancer histologic types. 

Thennavan A, Beca F, Xia Y, Recio SG, Allison K, Collins LC, Tse GM, Chen YY, Schnitt SJ, Hoadley KA, Beck A, Perou CM.

Cell Genom. 2021 Dec 8;1(3):100067. doi: 10.1016/j.xgen.2021.100067.

PMID: 35465400

 

Synthetic amyloid beta does not induce a robust transcriptional response in innate immune cell culture systems. 

Quiroga IY, Cruikshank AE, Bond ML, Reed KSM, Evangelista BA, Tseng JH, Ragusa JV, Meeker RB, Won H, Cohen S, Cohen TJ, Phanstiel DH.

J Neuroinflammation. 2022 Apr 23;19(1):99. doi: 10.1186/s12974-022-02459-1.

PMID: 35459147 Free PMC article.

 

Understanding Regulatory Mechanisms of Brain Function and Disease through 3D Genome Organization. 

Liu W, Zhong W, Chen J, Huang B, Hu M, Li Y.

Genes (Basel). 2022 Mar 25;13(4):586. doi: 10.3390/genes13040586.

PMID: 35456393 Free PMC article. Review.

 

A prospective study of asymptomatic SARS-CoV-2 infection among individuals involved in academic research under limited operations during the COVID-19 pandemic. 

Pettifor A, DiPrete BL, Shook-Sa BE, Premkumar L, Kuczynski K, Dittmer D, Aiello A, Wallet S, Maile R, Tan J, Jadi R, Pluta L, de Silva AM, Weber DJ, Kim M, Seña AC, Jones CD.

PLoS One. 2022 Apr 25;17(4):e0267353. doi: 10.1371/journal.pone.0267353. eCollection 2022.

PMID: 35468150 Free PMC article.

 

Information is power: The experiences, attitudes and needs of individuals who chose to have prenatal genomic sequencing for fetal anomalies. 

Kernie CG, Wynn J, Rosenbaum A, de Voest J, Galloway S, Giordano J, Stover S, Westerfield L, Gilmore K, Wapner RJ, Van den Veyver IB, Vora NL, Clifton RG, Caughey AB, Chung WK.

Prenat Diagn. 2022 Apr 27. doi: 10.1002/pd.6153. Online ahead of print.

PMID: 35476893

 

Model-based prediction of irinotecan-induced grade 4 neutropenia in advanced cancer patients: influence of demographic and clinical factors. 

Karas S, Mathijssen RHJ, van Schaik RHN, Forrest A, Wiltshire T, Innocenti F, Bies RR.

Clin Pharmacol Ther. 2022 Apr 25. doi: 10.1002/cpt.2621. Online ahead of print.

PMID: 35467016

 

The Gene Curation Coalition: A global effort to harmonize gene-disease evidence resources. 

DiStefano MT, Goehringer S, Babb L, Alkuraya FS, Amberger J, Amin M, Austin-Tse C, Balzotti M, Berg JS, Birney E, Bocchini C, Bruford EA, Coffey AJ, Collins H, Cunningham F, Daugherty LC, Einhorn Y, Firth HV, Fitzpatrick DR, Foulger RE, Goldstein J, Hamosh A, Hurles MR, Leigh SE, Leong IUS, Maddirevula S, Martin CL, McDonagh EM, Olry A, Puzriakova A, Radtke K, Ramos EM, Rath A, Riggs ER, Roberts AM, Rodwell C, Snow C, Stark Z, Tahiliani J, Tweedie S, Ware JS, Weller P, Williams E, Wright CF, Yates TM, Rehm HL.

Genet Med. 2022 May 4:S1098-3600(22)00746-8. doi: 10.1016/j.gim.2022.04.017. Online ahead of print.

PMID: 35507016

 

BIDIMENSIONAL LINKED MATRIX FACTORIZATION FOR PAN-OMICS PAN-CANCER ANALYSIS. 

Lock EF, Park JY, Hoadley KA.

Ann Appl Stat. 2022 Mar;16(1):193-215. doi: 10.1214/21-AOAS1495. Epub 2022 Mar 28.

PMID: 35505906 Free PMC article.

 

DNA Methylation Imputation Across Platforms. 

Li G, Zhang G, Li Y.

Methods Mol Biol. 2022;2432:137-151. doi: 10.1007/978-1-0716-1994-0_11.

PMID: 35505213 Review.

 

TOP-LD: A tool to explore linkage disequilibrium with TOPMed whole-genome sequence data. 

Huang L, Rosen JD, Sun Q, Chen J, Wheeler MM, Zhou Y, Min YI, Kooperberg C, Conomos MP, Stilp AM, Rich SS, Rotter JI, Manichaikul A, Loos RJF, Kenny EE, Blackwell TW, Smith AV, Jun G, Sedlazeck FJ, Metcalf G, Boerwinkle E; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, Raffield LM, Reiner AP, Auer PL, Li Y.

Am J Hum Genet. 2022 Apr 26:S0002-9297(22)00154-9. doi: 10.1016/j.ajhg.2022.04.006. Online ahead of print.

PMID: 35504290

 

Gaseous air pollutants and DNA methylation in a methylome-wide association study of an ethnically and environmentally diverse population of U.S. adults. 

Holliday KM, Gondalia R, Baldassari A, Justice AE, Stewart JD, Liao D, Yanosky JD, Jordahl KM, Bhatti P, Assimes TL, Pankow JS, Guan W, Fornage M, Bressler J, North KE, Conneely KN, Li Y, Hou L, Vokonas PS, Ward-Caviness CK, Wilson R, Wolf K, Waldenberger M, Cyrys J, Peters A, Boezen HM, Vonk JM, Sayols-Baixeras S, Lee M, Baccarelli AA, Whitsel EA.

Environ Res. 2022 Apr 29:113360. doi: 10.1016/j.envres.2022.113360. Online ahead of print.

PMID: 35500859

 

Dermal Lymphatic Capillaries Do Not Obey Murray’s Law. 

Talkington AM, Davis RB, Datto NC, Goodwin ER, Miller LA, Caron KM.

Front Cardiovasc Med. 2022 Apr 12;9:840305. doi: 10.3389/fcvm.2022.840305. eCollection 2022.

PMID: 35498025 Free PMC article.